A major quantitative trait locus on chromosome 3 controls colitis severity in IL-10-deficient mice.
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Central role of the gut epithelial barrier in the pathogenesis of chronic intestinal inflammation: lessons learned from animal models and human geneticsA Multihit Model: Colitis Lessons from the Interleukin-10-deficient MouseAn antibiotic-responsive mouse model of fulminant ulcerative colitisIntegrating mouse anatomy and pathology ontologies into a phenotyping database: tools for data capture and trainingA data-capture tool for mouse pathology phenotyping.Induction of bacterial antigen-specific colitis by a simplified human microbiota consortium in gnotobiotic interleukin-10-/- mice.Cdcs1 a major colitis susceptibility locus in mice; subcongenic analysis reveals genetic complexity.Quantitative lymphatic vessel trait analysis suggests Vcam1 as candidate modifier gene of inflammatory bowel disease.Microbiota activation and regulation of innate and adaptive immunity.Guanylate-binding protein-1 is expressed at tight junctions of intestinal epithelial cells in response to interferon-gamma and regulates barrier function through effects on apoptosis.Molecular control of steady-state dendritic cell maturation and immune homeostasis.Genetic background of IL-10(-/-) mice alters host-pathogen interactions with Campylobacter jejuni and influences disease phenotype.Analysis of candidate colitis genes in the Gdac1 locus of mice deficient in glutathione peroxidase-1 and -2.A model selection approach for expression quantitative trait loci (eQTL) mappingLinkage of Crohn's disease-related serological phenotypes: NFKB1 haplotypes are associated with anti-CBir1 and ASCA, and show reduced NF-kappaB activation.Severity of innate immune-mediated colitis is controlled by the cytokine deficiency-induced colitis susceptibility-1 (Cdcs1) locusCutting-edge technology: IV. Genomic engineering for studies of the gastrointestinal tract in mice.Mucosal immune responses following intestinal nematode infectionStatistical dissection of cyto-nuclear epistasis subject to genomic imprinting in line crosses.Interleukin-10-based therapy for inflammatory bowel disease.Optical reconstruction of murine colorectal mucosa at cellular resolution.Analysis of the IBD5 locus and potential gene-gene interactions in Crohn's disease.Soluble Dextrin Fibers Alter the Intestinal Microbiota and Reduce Proinflammatory Cytokine Secretion in Male IL-10-Deficient Mice.Diagnostic and Prognostic Microbial Biomarkers in Inflammatory Bowel Diseases.Gene disruption and immunity in experimental colitis.Genetics of Crohn disease, an archetypal inflammatory barrier disease.Colitis locus on chromosome 2 impacting the severity of early-onset disease in mice deficient in GPX1 and GPX2.Role of genes, the environment and their interactions in the etiology of inflammatory bowel diseases.Interleukin 10 receptor signaling: master regulator of intestinal mucosal homeostasis in mice and humans.Genetic analysis of the Trichuris muris-induced model of colitis reveals QTL overlap and a novel gene cluster for establishing colonic inflammationAlterations in myeloid dendritic cell innate immune responses in the Galphai2-deficient mouse model of colitis.Quantitative trait loci in a bacterially induced model of inflammatory bowel disease.Mouse genome-wide association study identifies polymorphisms on chromosomes 4, 11, and 15 for age-related cardiac fibrosis.The Collaborative Cross as a resource for modeling human disease: CC011/Unc, a new mouse model for spontaneous colitis.Mapping colitis susceptibility in mouse models: distal chromosome 3 contains major loci related to Cdcs1.Rodent intestinal epithelial carcinogenesis: pathology and preclinical models.Cd14, Gbp1, and Pla2g2a: three major candidate genes for experimental IBD identified by combining QTL and microarray analyses.Functional annotation of a novel NFKB1 promoter polymorphism that increases risk for ulcerative colitis.From Genes to Mechanisms: The Expanding Spectrum of Monogenic Disorders Associated with Inflammatory Bowel Disease.Analysis of Cd14 as a genetic modifier of experimental inflammatory bowel disease (IBD) in mice.
P2860
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P2860
A major quantitative trait locus on chromosome 3 controls colitis severity in IL-10-deficient mice.
description
2001 nî lūn-bûn
@nan
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
A major quantitative trait loc ...... erity in IL-10-deficient mice.
@ast
A major quantitative trait loc ...... erity in IL-10-deficient mice.
@en
type
label
A major quantitative trait loc ...... erity in IL-10-deficient mice.
@ast
A major quantitative trait loc ...... erity in IL-10-deficient mice.
@en
prefLabel
A major quantitative trait loc ...... erity in IL-10-deficient mice.
@ast
A major quantitative trait loc ...... erity in IL-10-deficient mice.
@en
P2093
P2860
P356
P1476
A major quantitative trait loc ...... erity in IL-10-deficient mice.
@en
P2093
E H Leiter
G A Churchill
I J Bristol
J P Sundberg
M A Farmer
P2860
P304
13820-13825
P356
10.1073/PNAS.241258698
P407
P577
2001-11-13T00:00:00Z