Functional relevance of carnitine transporter OCTN2 to brain distribution of L-carnitine and acetyl-L-carnitine across the blood-brain barrier.
about
Effects of oral L-carnitine administration in narcolepsy patients: a randomized, double-blind, cross-over and placebo-controlled trialTransporters at CNS barrier sites: obstacles or opportunities for drug delivery?Localization of organic cation/carnitine transporter (OCTN2) in cells forming the blood-brain barrier.Development of neuropeptide drugs that cross the blood-brain barrier.Active efflux across the blood-brain barrier: role of the solute carrier family.Xenobiotic, bile acid, and cholesterol transporters: function and regulation.Imperatorin is Transported through Blood-Brain Barrier by Carrier-Mediated Transporters.Inhibitory effects of alcohol on glucose transport across the blood-brain barrier leads to neurodegeneration: preventive role of acetyl-L: -carnitineMitochondrial dysfunction in Kennedy's disease: a new pharmacological target?Blood-brain barrier endogenous transporters as therapeutic targets: a new model for small molecule CNS drug discovery.Acetyl-L-carnitine treatment following spinal cord injury improves mitochondrial function correlated with remarkable tissue sparing and functional recovery.Mechanism of age-dependent susceptibility and novel treatment strategy in glutaric acidemia type IVitamins and nutrients as primary treatments in experimental brain injury: Clinical implications for nutraceutical therapies.Metabolism of acetyl-L-carnitine for energy and neurotransmitter synthesis in the immature rat brain.L-acetylcarnitine: a proposed therapeutic agent for painful peripheral neuropathiesToward a systems level understanding of organic anion and other multispecific drug transporters: a remote sensing and signaling hypothesis.The transport of anti-HIV drugs across blood-CNS interfaces: summary of current knowledge and recommendations for further research.Role of membrane transporters in the safety profile of drugs.Nanostructure-based drug delivery systems for brain targeting.OCTN cation transporters in health and disease: role as drug targets and assay development.Drug transporters in the central nervous system."Boomerang Neuropathology" of Late-Onset Alzheimer's Disease is Shrouded in Harmful "BDDS": Breathing, Diet, Drinking, and Sleep During Aging.Modification of Astrocyte Metabolism as an Approach to the Treatment of Epilepsy: Triheptanoin and Acetyl-L-Carnitine.The Role of Transporters in the Toxicity of Chemotherapeutic Drugs: Focus on Transporters for Organic Cations.Solute Carriers in the Blood-Brain Barier: Safety in Abundance.The poorly membrane permeable antipsychotic drugs amisulpride and sulpiride are substrates of the organic cation transporters from the SLC22 family.The acetylcholinesterase inhibitors competitively inhibited an acetyl L-carnitine transport through the blood-brain barrier.A prospective, proof-of-concept investigation of KPAX002 in chronic fatigue syndrome.Interaction between anticonvulsants and human placental carnitine transporter.In vivo neuroprotective effect of L-carnitine against oxidative stress in maple syrup urine disease.The effect of the mode of delivery on the maternal-neonatal carnitine blood levels and antioxidant status.In vivo evidence for the efflux transport of pentazocine from the brain across the blood-brain barrier using the brain efflux index method.Valproate and acetyl-L-carnitine prevent methamphetamine-induced behavioral sensitization in mice.L-Carnitine-conjugated nanoparticles to promote permeation across blood-brain barrier and to target glioma cells for drug delivery via the novel organic cation/carnitine transporter OCTN2.Transporter-Guided Delivery of Nanoparticles to Improve Drug Permeation across Cellular Barriers and Drug Exposure to Selective Cell Types.Neuroprotective Effects of Acetyl-L-Carnitine Against Oxygen-Glucose Deprivation-Induced Neural Stem Cell Death.l-Carnitine Modulates Epileptic Seizures in Pentylenetetrazole-Kindled Rats via Suppression of Apoptosis and Autophagy and Upregulation of Hsp70.Solute Carrier (SLC) Family Transporters
P2860
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P2860
Functional relevance of carnitine transporter OCTN2 to brain distribution of L-carnitine and acetyl-L-carnitine across the blood-brain barrier.
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Functional relevance of carnit ...... cross the blood-brain barrier.
@ast
Functional relevance of carnit ...... cross the blood-brain barrier.
@en
type
label
Functional relevance of carnit ...... cross the blood-brain barrier.
@ast
Functional relevance of carnit ...... cross the blood-brain barrier.
@en
prefLabel
Functional relevance of carnit ...... cross the blood-brain barrier.
@ast
Functional relevance of carnit ...... cross the blood-brain barrier.
@en
P2093
P2860
P1476
Functional relevance of carnit ...... cross the blood-brain barrier.
@en
P2093
Hashimoto N
P2860
P304
P356
10.1046/J.1471-4159.2001.00621.X
P407
P577
2001-12-01T00:00:00Z