Smg1 is required for embryogenesis and regulates diverse genes via alternative splicing coupled to nonsense-mediated mRNA decay. - Test2 - elhamkhani - TriplyDB

Smg1 is required for embryogenesis and regulates diverse genes via alternative splicing coupled to nonsense-mediated mRNA decay.

Smg1 is required for embryogenesis and regulates diverse genes via alternative splicing coupled to nonsense-mediated mRNA decay.

http://www.wikidata.org/entity/Q33982260

about

Nonsense-mediated mRNA decay: novel mechanistic insights and biological impact Mechanism and regulation of the nonsense-mediated decay pathway The combined human sperm proteome: cellular pathways and implications for basic and clinical science Nonsense-mediated mRNA decay: inter-individual variability and human disease Retroviral strategy to stabilize viral RNA SMG-1 and mTORC1 act antagonistically to regulate response to injury and growth in planarians Nonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the Story Introns in UTRs: why we should stop ignoring them Attenuation of nonsense-mediated mRNA decay enhances in vivo nonsense suppression Mutations in SMG9, Encoding an Essential Component of Nonsense-Mediated Decay Machinery, Cause a Multiple Congenital Anomaly Syndrome in Humans and Mice Eukaryotic initiation factor 4G suppresses nonsense-mediated mRNA decay by two genetically separable mechanisms Widespread intron retention in mammals functionally tunes transcriptomes RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis.Downregulation of SMG-1 in HPV-positive head and neck squamous cell carcinoma due to promoter hypermethylation correlates with improved survival.Ribosome-omics of the human ribosome.Intracellular calcium regulates nonsense-mediated mRNA decay.iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS SMG1 acts as a novel potential tumor suppressor with epigenetic inactivation in acute myeloid leukemia.RNA homeostasis governed by cell type-specific and branched feedback loops acting on NMD.Deep brain stimulation modulates nonsense-mediated RNA decay in Parkinson's patients leukocytes Identification of a microRNA that activates gene expression by repressing nonsense-mediated RNA decay.Nonsense-mediated mRNA decay (NMD) in animal embryogenesis: to die or not to die, that is the question.A feedback loop between nonsense-mediated decay and the retrogene DUX4 in facioscapulohumeral muscular dystrophy.Suppression of nonsense mutations as a therapeutic approach to treat genetic diseases.A novel role for hSMG-1 in stress granule formation Nonsense-mediated RNA decay--a switch and dial for regulating gene expression Methylxanthines Increase Expression of the Splicing Factor SRSF2 by Regulating Multiple Post-transcriptional Mechanisms Smg6/Est1 licenses embryonic stem cell differentiation via nonsense-mediated mRNA decay.A critical role of RBM8a in proliferation and differentiation of embryonic neural progenitors.A conserved microRNA/NMD regulatory circuit controls gene expression.Aberrant growth and lethality of Arabidopsis deficient in nonsense-mediated RNA decay factors is caused by autoimmune-like response.MicroRNA 433 regulates nonsense-mediated mRNA decay by targeting SMG5 mRNA.Mammalian tissues defective in nonsense-mediated mRNA decay display highly aberrant splicing patterns Caspases shutdown nonsense-mediated mRNA decay during apoptosis.Smg1 haploinsufficiency predisposes to tumor formation and inflammation.A novel AKT inhibitor, AZD5363, inhibits phosphorylation of AKT downstream molecules, and activates phosphorylation of mTOR and SMG-1 dependent on the liver cancer cell type.Inhibition of nonsense-mediated RNA decay activates autophagy.A dynamic intron retention program in the mammalian megakaryocyte and erythrocyte lineages Regulation of nonsense-mediated mRNA decay: implications for physiology and disease.Evolutionarily conserved autoregulation of alternative pre-mRNA splicing by ribosomal protein L10a

P2860

Q26750271-DC938C7D-6BB6-4EF2-A88F-D274A075CC5A Q26771669-19AC5D95-14F7-470B-8CB9-7A1E5623AD77 Q26851366-1160DC70-50D0-4A0A-8221-3959DF2C4975 Q27015298-F26BC7D5-1E19-45E5-86ED-E392DD353CBA Q27022549-B3BD03DA-3392-457B-B0D3-BA3DF79D3FE0 Q27334311-B291AF89-9375-4051-A44E-6F93CCEB7EAB Q28082699-838B3558-CD31-4E6D-A191-59A69E21D35B Q28278199-0C83CACC-A1E3-4224-A897-37936DC13DC4 Q28486134-27194D87-F88F-4F30-9FCB-0112BB0CE82D Q28513439-E4107E47-5851-4AF7-A48F-B95A7F4D8001 Q28542512-7EE39E56-CAC4-4AB0-8887-CA924FFBF67B Q28652843-55A1BB89-D0BD-4398-905E-657D8073EF4E Q30836611-8BFF3FED-191A-4870-9455-BE33E10529AC Q33566949-31AC15FB-3CB5-483D-A955-CAF7D81DEEE9 Q33967907-18430642-C9AC-464D-B5E7-557155CE85A9 Q34021019-CD3629ED-CAEF-4DB9-9C7D-2BAC5E73287D Q34247201-AA76F054-E9E0-4BD4-A9E1-1616254A1A20 Q34356687-55A8C3BF-485E-4F69-8558-C5D8DE620970 Q34796040-BF8926E3-A712-45E3-869B-0CD8AEE86991 Q34831484-6D2A9AA3-AA06-407D-A07A-CC79CCCE1806 Q35067929-45C8E520-4819-4E66-82AA-92DBD4067827 Q35148086-E39984C3-F748-4B06-8EAB-82B41D7E7F2C Q35249502-18E3DB6D-48E9-4C94-9D0C-A74DE86949B6 Q35287888-4C9FD7D5-596C-4E4B-88C7-A1C98484CDD0 Q35531069-571554AB-7C4E-48BC-BBC2-F6CF086F2796 Q35679722-3E06CF0F-0613-49BE-9655-DAED235C4838 Q35721733-12B511B1-631B-4482-BB2D-346264AE82E9 Q35762628-15044D1F-37A7-43F5-AE9F-DA8050214E8B Q35775587-1480EC26-83E1-489D-9E78-FEAB1F57B080 Q35930508-58ABC78F-6D19-4061-AFC5-287318A6BCEE Q36061891-0683AC63-1520-461E-9980-AE01A565CED3 Q36090334-32FCBEF1-A18C-49F9-B0A3-807735B21D6E Q36245213-21C5F2B0-C3B2-40AC-AEF8-243231CAE50B Q36288298-FEB478E7-DA4B-46F0-A373-FD43D9FD441B Q36568009-372B2890-9658-4900-85F1-CB2416497EAA Q36640327-F5902EF5-567A-4CBC-8399-460F2292A6FB Q36827114-7BEA22C5-1358-4210-91A2-9E344E4E913D Q36851409-F173C553-7125-47D2-9A62-9184EDA6AD0A Q36864323-3BD41444-0361-4B97-BA58-090E4EEFD64D Q37076262-9C43589E-E23B-4990-A77D-2B39C3AC4E56

P2860

Smg1 is required for embryogenesis and regulates diverse genes via alternative splicing coupled to nonsense-mediated mRNA decay.

http://www.wikidata.org/entity/Q33982260

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Smg1 is required for embryogen ...... nonsense-mediated mRNA decay.

@ast

Smg1 is required for embryogen ...... nonsense-mediated mRNA decay.

@en

type

label

Smg1 is required for embryogen ...... nonsense-mediated mRNA decay.

@ast

Smg1 is required for embryogen ...... nonsense-mediated mRNA decay.

@en

prefLabel

Smg1 is required for embryogen ...... nonsense-mediated mRNA decay.

@ast

Smg1 is required for embryogen ...... nonsense-mediated mRNA decay.

@en

P1433

Q33982260-2F714D6A-4950-45A0-B148-DE490DEDEB19

P1476

Q33982260-8908C461-CA88-4BB2-AAA9-ACE59B063B29

P2093

Q33982260-11BAFEDE-0981-4FA0-92DF-B4305A473750

Q33982260-22AB633F-AFCA-4B85-B1AA-6AC7CDC3B149

Q33982260-3534E6CC-AA39-4C13-8A43-C96B7F970601

Q33982260-B5D3CD3D-1E00-4038-90F2-8387A797CA83

Q33982260-B62EFDB4-AF90-4083-9BBF-3C1676474A2F

Q33982260-C3233693-6633-42B0-B766-4C30D060728E

Q33982260-D7FECC9F-57B6-4A22-8D27-0471113760CA

Q33982260-DAFF4EA7-FEB8-4486-898C-2CEC4E51291F

Q33982260-DEBCC997-815A-482D-B255-0DD178D07354

P2860

Q33982260-0A63DEEF-D607-4CEC-BA99-A23423AD10C3

Q33982260-0FE23AD4-C2FD-434D-8524-061A75EB2409

Q33982260-1F7B76C4-B2A4-4D9B-A6E8-894866C5B0BD

Q33982260-219FD1DC-2794-4C68-90A5-06FCC9B53FF7

Q33982260-246127FE-F82B-4AFC-AD67-942F44997A97

Q33982260-262E0C53-F80C-4F95-87AF-0EB0141F65E3

Q33982260-2BF23E95-6CC8-427E-A327-29AFFBA34445

Q33982260-33623A6F-9DB7-4B1E-A3E9-3932CA038FF5

Q33982260-358CAD0E-AF88-4FA4-ADBC-EFCE22C99D2B

Q33982260-385233F9-E110-4231-966C-229D5CA20D21

P304

Q33982260-9B90B207-0372-450B-966B-88DDA2BDF0ED

P31

Q33982260-A9875DF8-F890-4FE8-BAE8-BBFAFF8BADBA

P356

Q33982260-2671BFB5-F12D-408B-9972-450377D83417

P407

Q33982260-3EAA4989-A3AB-4A36-87D0-3663276F8685

P433

Q33982260-BCD9A8AB-DA01-4B9D-9BC6-23C3CB18B487

P478

Q33982260-096AF744-0D87-4683-8FF6-C9659FA24EDD

P577

Q33982260-3B87EC95-EC82-4113-8F8E-69325FE231FD

P5875

Q33982260-593ADE3F-CA06-484D-9692-C90D6D6385B4

P698

Q33982260-43AB0417-C84B-41A8-993C-3F8233E315E8

P921

Q33982260-EC8B8AB2-8137-4FD7-849C-41B334B14C2F

P932

Q33982260-C8FF3379-1A4A-44F3-B1E4-C35E3B4F1538

P356

PNAS.1007336107

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Smg1 is required for embryogen ...... nonsense-mediated mRNA decay.

@en

P2093

Andrew C Wakeham

http://www.w3.org/2001/XMLSchema#string

Andrew J Elia

http://www.w3.org/2001/XMLSchema#string

Annick Itie-Youten

http://www.w3.org/2001/XMLSchema#string

Benjamin J Blencowe

http://www.w3.org/2001/XMLSchema#string

David R McIlwain

http://www.w3.org/2001/XMLSchema#string

Patrick T Reilly

http://www.w3.org/2001/XMLSchema#string

Qun Pan

http://www.w3.org/2001/XMLSchema#string

Susan McCracken

http://www.w3.org/2001/XMLSchema#string

Tak W Mak

http://www.w3.org/2001/XMLSchema#string

P2860

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

Cloning of a novel phosphatidylinositol kinase-related kinase: characterization of the human SMG-1 RNA surveillance protein

Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay

The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells

Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay

RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis.

Common mechanisms of PIKK regulation

The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse

Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends

Functions of the nonsense-mediated mRNA decay pathway in Drosophila development

P304

12186-12191

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.1007336107

http://www.w3.org/2001/XMLSchema#string

P407

P433

27

http://www.w3.org/2001/XMLSchema#string

P478

107

http://www.w3.org/2001/XMLSchema#string

P577

2010-06-21T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

44691314

http://www.w3.org/2001/XMLSchema#string

P698

20566848

http://www.w3.org/2001/XMLSchema#string

P921

P932

2901484

http://www.w3.org/2001/XMLSchema#string