Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA - Test2 - elhamkhani - TriplyDB

Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA

Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA

http://www.wikidata.org/entity/Q33987569

about

Genetic studies of body mass index yield new insights for obesity biology GWAS of 126,559 individuals identifies genetic variants associated with educational attainment Expression Quantitative Trait Loci Information Improves Predictive Modeling of Disease Relevance of Non-Coding Genetic Variation Interrogating the major histocompatibility complex with high-throughput genomics From integrative genomics to systems genetics in the rat to link genotypes to phenotypes Hematopoietic Signaling Mechanism Revealed from a Stem/Progenitor Cell Cistrome A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease Characterizing the genetic basis of transcriptome diversity through RNA-sequencing of 922 individuals Pleiotropy in complex traits: challenges and strategies Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci Persistently active microbial molecules prolong innate immune tolerance in vivo Mixed effects modeling of proliferation rates in cell-based models: consequence for pharmacogenomics and cancer Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway RNA Sequencing and Analysis Genetics of gene expression in immunity to infection Trans-ethnic meta-analysis of white blood cell phenotypes Systematic identification of trans eQTLs as putative drivers of known disease associations Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals.Common genes underlying asthma and COPD? Genome-wide analysis on the Dutch hypothesis.Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.Analyzing illumina gene expression microarray data from different tissues: methodological aspects of data analysis in the metaxpress consortium Normalizing RNA-sequencing data by modeling hidden covariates with prior knowledge.Calling genotypes from public RNA-sequencing data enables identification of genetic variants that affect gene-expression levels Integration of Genome-Wide SNP Data and Gene-Expression Profiles Reveals Six Novel Loci and Regulatory Mechanisms for Amino Acids and Acylcarnitines in Whole Blood.An interaction quantitative trait loci tool implicates epistatic functional variants in an apoptosis pathway in smallpox vaccine eQTL data.Solving the genetic puzzle of systemic lupus erythematosus.Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs.Heritability and genomics of gene expression in peripheral blood.An independent component analysis confounding factor correction framework for identifying broad impact expression quantitative trait loci Variants in exons and in transcription factors affect gene expression in trans.Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression Large-scale East-Asian eQTL mapping reveals novel candidate genes for LD mapping and the genomic landscape of transcriptional effects of sequence variants Coexpression and expression quantitative trait loci analyses of the angiogenesis gene-gene interaction network in prostate cancer.Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations Copper metabolism domain-containing 1 represses genes that promote inflammation and protects mice from colitis and colitis-associated cancer Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease.Synthesis of 53 tissue and cell line expression QTL datasets reveals master eQTLs.Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression.The functional significance of common polymorphisms in zinc finger transcription factors

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Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA

http://www.wikidata.org/entity/Q33987569

description

2011 nî lūn-bûn

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2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի օգոստոսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Trans-eQTLs reveal that indepe ...... with a major role for the HLA

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JOURNAL.PGEN.1002197

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Trans-eQTLs reveal that indepe ...... with a major role for the HLA

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Asia Smolonska

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Christiaan G J Saris

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Clara C Elbers

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Eleanora M Festen

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Gerard J Te Meerman

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Harry J M Groen

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Marcel G M Wolfs

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Marten H Hofker

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Rinse K Weersma

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P2860

Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS

SHRiMP: accurate mapping of short color-space reads

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

Recent advances in coeliac disease

Common variants at five new loci associated with early-onset inflammatory bowel disease

Multiple common variants for celiac disease influencing immune gene expression

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

Several loci in the HLA class III region are associated with T1D risk after adjusting for DRB1-DQB1

Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study

Genome-wide association study identifies novel breast cancer susceptibility loci

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8

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Harm-Jan Westra

Alexandra Zhernakova

David A van Heel

Marc Jan Bonder

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2011-08-04T00:00:00Z

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