Requirement for both Shc and phosphatidylinositol 3' kinase signaling pathways in polyomavirus middle T-mediated mammary tumorigenesis.
about
Use of signal specific receptor tyrosine kinase oncoproteins reveals that pathways downstream from Grb2 or Shc are sufficient for cell transformation and metastasisMatrix crosslinking forces tumor progression by enhancing integrin signalingMammary tumorigenesis and metastasis caused by overexpression of insulin receptor substrate 1 (IRS-1) or IRS-2Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasisMolecular analysis of metastasis in a polyomavirus middle T mouse model: the role of osteopontinDo we now have a relevant animal model for breast cancer?Phosphoinositide 3-kinase signalling in breast cancer: how big a role might it play?Tyrosine kinase signalling in breast cancer: tyrosine kinase-mediated signal transduction in transgenic mouse models of human breast cancer.JNK signalling in cancer: in need of new, smarter therapeutic targetsSubversion of Cell Signaling Pathways by Hepatitis C Virus Nonstructural 5A Protein via Interaction with Grb2 and P85 Phosphatidylinositol 3-KinaseStromal characteristics may hold the key to mammographic density: the evidence to dateSam68 haploinsufficiency delays onset of mammary tumorigenesis and metastasisShcA and Grb2 mediate polyoma middle T antigen-induced endothelial transformation and Gab1 tyrosine phosphorylation.'Srcasm: a novel Src activating and signaling moleculeShcA signalling is essential for tumour progression in mouse models of human breast cancerJnk2 effects on tumor development, genetic instability and replicative stress in an oncogene-driven mouse mammary tumor model.Mechanisms of cell transformation induced by polyomavirus.Signal transduction in mammary tumorigenesis: a transgenic perspective.Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancerNatural biology of polyomavirus middle T antigen.Accelerated mammary tumor development in mutant polyomavirus middle T transgenic mice expressing elevated levels of either the Shc or Grb2 adapter protein.Grb2 and Shc adapter proteins play distinct roles in Neu (ErbB-2)-induced mammary tumorigenesis: implications for human breast cancerActivation of Akt (protein kinase B) in mammary epithelium provides a critical cell survival signal required for tumor progression.Pilot study on the effects of dietary conjugated linoleic acid on tumorigenesis and gene expression in PyMT transgenic mice.Akt1 and akt2 play distinct roles in the initiation and metastatic phases of mammary tumor progressionRemodeling of endogenous mammary epithelium by breast cancer stem cellsThe PTEN/PI3K/AKT Pathway in vivo, Cancer Mouse Models.The phosphatidylinositol 3-kinase (PI3K) isoform dependence of tumor formation is determined by the genetic mode of PI3K pathway activation rather than by tissue type.Control of mammary tumor differentiation by SKI-606 (bosutinib).Introduction of oncogenes into mammary glands in vivo with an avian retroviral vector initiates and promotes carcinogenesis in mouse models.Loss of TGF-beta type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-alpha-, MSP- and HGF-mediated signaling networksBlockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases.Loss of caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic micec-Jun N-terminal kinase 2 (JNK2) enhances cell migration through epidermal growth factor substrate 8 (EPS8).Transgenic expression of polyomavirus middle T antigen in the mouse prostate gives rise to carcinoma.Cellular transformation by Simian Virus 40 and Murine Polyoma Virus T antigens.Profiling the tyrosine phosphoproteome of different mouse mammary tumour models reveals distinct, model-specific signalling networks and conserved oncogenic pathways.Lessons in signaling and tumorigenesis from polyomavirus middle T antigen.Differential sensitivity of mouse epithelial tissues to the polyomavirus middle T oncogene.Amplification of the neu/erbB-2 oncogene in a mouse model of mammary tumorigenesis.
P2860
Q24292477-3F42962E-DD8F-4D7D-9D79-DD784F5EDE75Q24646370-693FC6ED-3CCC-4E7A-88ED-075442DEE40FQ24672372-DB39DD79-B23C-4F6A-80E7-1FC69570AE51Q24679619-96CBD37B-7717-482D-80B9-1F310E9C9F57Q24794607-4185C330-2B12-4BAF-A557-5F2EA8BA2FCEQ24800439-25F33BBF-5E98-4AD6-91D6-5CB1F1353826Q24801684-7335EC7A-862F-4D8A-9CAF-CE49EB97639BQ24803081-3104D7CE-03E2-4B7B-9A7D-A4ACB9010E6BQ27023869-BE684002-3C26-4AB6-AD1C-3A3D722A846FQ27472897-BD501F3E-4120-454A-83C5-D9D44A9E8EDFQ28066162-3069ED5C-4E5A-46BC-8847-31C9B17591D0Q28235894-C97EE5F6-5303-48AB-87F7-49F6C414C9B9Q28364018-D6E3ADF4-BBB7-4D77-8F98-449D49F794B5Q28505622-2EEA8012-134D-420F-BDDE-E899450B7C4EQ28590157-37A3AC70-0083-47A7-B771-08B4C96BF598Q33573421-EA9D0A87-569B-4248-8BD7-6D10FFEDFB7AQ33716355-171D7B49-586C-4EA0-96D1-314BC04C2A6DQ33860827-8D555E64-E2B9-4C2F-AEA8-205E8E352863Q33890758-A6B37EA8-7696-49B9-BFDF-3990A659115EQ33948870-35519F90-5D65-4268-9CD9-78DD77B531E3Q33960624-3DF6E712-122F-4F84-9081-4CBB0E67218EQ33967189-944D93F3-B667-478A-8C2B-0E91B5FBBEFFQ33967736-87A305EE-D7E4-4B43-9E9A-0A8771A91C3CQ34094999-E6E9FE58-8BCB-4D6D-A424-6B64D74DDCE8Q34118999-F37FFF07-3C88-42BA-B215-B9B04542C7ACQ34154365-C6BFD5C9-DB04-4C46-981A-3DB5B4A6A87CQ34229795-60EB7AEF-DF6B-44A7-B785-EBC6F2302BA7Q34262144-4C2C4DEE-E05F-401A-AA89-A8144296FE1DQ34398204-F1CE3AAF-7F1B-49CC-AC37-77D8BD9CFE20Q34580042-ED796A75-F002-4BB8-B47D-F33E987B47A4Q34781947-84ECDA65-095E-475A-A77F-FEE6E112FE5AQ34792468-AD93113A-4629-4100-B792-3EC5969F15E7Q34813351-826DBDDD-B7C8-43FD-930A-86C4CC2D19E5Q34869169-FD2275CF-9769-4056-B2A1-D268847A1757Q34982720-9194F870-778E-4E52-9BED-3507BB67F759Q34985587-E9AB19C8-47FD-47B9-A1E0-7E96B824DC92Q35000261-0A2678F4-EFBF-4FD7-8D2C-24B28805F0DAQ35000523-9C7B8DD7-9093-45DB-91C0-802A184C767FQ35070697-6296BA4B-6CFE-4AF3-B7D8-BAECB742CBFAQ35112126-C5ED8694-0FB4-4B75-8545-4D30D390CF39
P2860
Requirement for both Shc and phosphatidylinositol 3' kinase signaling pathways in polyomavirus middle T-mediated mammary tumorigenesis.
description
1998 nî lūn-bûn
@nan
1998 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Requirement for both Shc and p ...... ediated mammary tumorigenesis.
@ast
Requirement for both Shc and p ...... ediated mammary tumorigenesis.
@en
type
label
Requirement for both Shc and p ...... ediated mammary tumorigenesis.
@ast
Requirement for both Shc and p ...... ediated mammary tumorigenesis.
@en
prefLabel
Requirement for both Shc and p ...... ediated mammary tumorigenesis.
@ast
Requirement for both Shc and p ...... ediated mammary tumorigenesis.
@en
P2093
P2860
P356
P1476
Requirement for both Shc and p ...... ediated mammary tumorigenesis.
@en
P2093
C G Tortorice
F L Graham
J A Hassell
J N Hutchinson
M A Webster
R D Cardiff
S K Muthuswamy
W J Muller
P2860
P304
P356
10.1128/MCB.18.4.2344
P407
P577
1998-04-01T00:00:00Z