Normal human pluripotent stem cell lines exhibit pervasive mosaic aneuploidy - Test2 - elhamkhani - TriplyDB

Normal human pluripotent stem cell lines exhibit pervasive mosaic aneuploidy

Normal human pluripotent stem cell lines exhibit pervasive mosaic aneuploidy

http://www.wikidata.org/entity/Q33999117

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Very small embryonic-like stem cells purified from umbilical cord blood lack stem cell characteristics Setting Up a Haplobank: Issues and Solutions Murine and human very small embryonic-like cells: a perspective Elevated tolerance to aneuploidy in cancer cells: estimating the fitness effects of chromosome number alterations by in silico modelling of somatic genome evolution Accuracy of preimplantation genetic screening (PGS) is compromised by degree of mosaicism of human embryos Genetic and epigenetic instability in human pluripotent stem cells.SNP array profiling of mouse cell lines identifies their strains of origin and reveals cross-contamination and widespread aneuploidy.Culture conditions affect cardiac differentiation potential of human pluripotent stem cells.Genomic mosaicism with increased amyloid precursor protein (APP) gene copy number in single neurons from sporadic Alzheimer's disease brains.Cardiac Stem Cell Hybrids Enhance Myocardial Repair.Implications of aneuploidy for stem cell biology and brain therapeutics Screening of human pluripotent stem cells using CGH and FISH reveals low-grade mosaic aneuploidy and a recurrent amplification of chromosome 1q.Spindle checkpoint deficiency is tolerated by murine epidermal cells but not hair follicle stem cells.Aneuploid cells are differentially susceptible to caspase-mediated death during embryonic cerebral cortical development.The genomically mosaic brain: aneuploidy and more in neural diversity and disease.Human mesenchymal stem cell-replicative senescence and oxidative stress are closely linked to aneuploidy Genomic instability in pluripotent stem cells: implications for clinical applications.Concise review: Genomic instability in human stem cells: current status and future challenges.Making it stick: chasing the optimal stem cells for cardiac regeneration.Chromosome instability in mouse embryonic stem cells.Cancer quasispecies and stem-like adaptive aneuploidy.Achilles' heel of pluripotent stem cells: genetic, genomic and epigenetic variations during prolonged culture.The tumorigenic potential of pluripotent stem cells: What can we do to minimize it?Points to consider in the development of seed stocks of pluripotent stem cells for clinical applications: International Stem Cell Banking Initiative (ISCBI).Low-grade chromosomal mosaicism in human somatic and embryonic stem cell populations.EZ spheres: a stable and expandable culture system for the generation of pre-rosette multipotent stem cells from human ESCs and iPSCs.Different RNA and protein expression of surface markers in rabbit amniotic fluid-derived mesenchymal stem cells.Mosaic autosomal aneuploidies are detectable from single-cell RNAseq data.Acquired Genetic and Epigenetic Variation in Human Pluripotent Stem Cells.Behavioral Variability and Somatic Mosaicism: A Cytogenomic Hypothesis.Expected advances in human fertility treatments and their likely translational consequences.

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Normal human pluripotent stem cell lines exhibit pervasive mosaic aneuploidy

http://www.wikidata.org/entity/Q33999117

description

2011 nî lūn-bûn

@nan

2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի օգոստոսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Normal human pluripotent stem cell lines exhibit pervasive mosaic aneuploidy

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Normal human pluripotent stem cell lines exhibit pervasive mosaic aneuploidy

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type

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Normal human pluripotent stem cell lines exhibit pervasive mosaic aneuploidy

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Normal human pluripotent stem cell lines exhibit pervasive mosaic aneuploidy

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prefLabel

Normal human pluripotent stem cell lines exhibit pervasive mosaic aneuploidy

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Normal human pluripotent stem cell lines exhibit pervasive mosaic aneuploidy

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JOURNAL.PONE.0023018

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Normal human pluripotent stem cell lines exhibit pervasive mosaic aneuploidy

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Candace L Lynch

http://www.w3.org/2001/XMLSchema#string

Christine M Paczkowski

http://www.w3.org/2001/XMLSchema#string

Diane M Bushman

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Ha T Tran

http://www.w3.org/2001/XMLSchema#string

Holly Young

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Jeanne F Loring

http://www.w3.org/2001/XMLSchema#string

Jerold Chun

http://www.w3.org/2001/XMLSchema#string

Jurjen W Westra

http://www.w3.org/2001/XMLSchema#string

Kyle S Nickey

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Louise C Laurent

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P2860

Multicolor Spectral Karyotyping of Human Chromosomes

Aneuploid neurons are functionally active and integrated into brain circuitry

Chromosomal variation in neurons of the developing and adult mammalian nervous system

Human DNA methylomes at base resolution show widespread epigenomic differences

Induced pluripotent stem cell lines derived from human somatic cells

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

Embryonic stem cell lines derived from human blastocysts

Role of Filia, a maternal effect gene, in maintaining euploidy during cleavage-stage mouse embryogenesis

In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state

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3156708

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