Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: implications for vaccine-based therapies for Alzheimer's disease.
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Variant of TREM2 Associated with the Risk of Alzheimer's DiseaseGenetics ignite focus on microglial inflammation in Alzheimer's diseaseOsteoimmunology: Major and Costimulatory Pathway Expression Associated with Chronic Inflammatory Induced Bone LossFunctional involvement of γ-secretase in signaling of the triggering receptor expressed on myeloid cells-2 (TREM2).Targeting neuroinflammation in Alzheimer's diseaseTemporal-logic analysis of microglial phenotypic conversion with exposure to amyloid-β.Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2.Harnessing pain heterogeneity and RNA transcriptome to identify blood-based pain biomarkers: a novel correlational study design and bioinformatics approach in a graded chronic constriction injury model.Differentiation of mouse bone marrow derived stem cells toward microglia-like cells.The rare TREM2 R47H variant exerts only a modest effect on Alzheimer disease risk.Upregulation of TREM2 ameliorates neuropathology and rescues spatial cognitive impairment in a transgenic mouse model of Alzheimer's diseaseAttenuated inflammatory response in triggering receptor expressed on myeloid cells 2 (TREM2) knock-out mice following stroke.Frontobasal gray matter loss is associated with the TREM2 p.R47H variantA neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse modelDevelopment of a culture system to induce microglia-like cells from haematopoietic cells.The evolving biology of microglia in Alzheimer's disease.ProphNet: a generic prioritization method through propagation of informationDifferent mechanisms of apolipoprotein E isoform-dependent modulation of prostaglandin E2 production and triggering receptor expressed on myeloid cells 2 (TREM2) expression after innate immune activation of microglia.TREM2 Protein Expression Changes Correlate with Alzheimer's Disease Neurodegenerative Pathologies in Post-Mortem Temporal CorticesRNA-sequencing reveals transcriptional up-regulation of Trem2 in response to bexarotene treatment.A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology.The triggering receptor expressed on myeloid cells 2 (TREM2) is associated with enhanced inflammation, neuropathological lesions and increased risk for Alzheimer's dementiaTREM2 regulates microglial cell activation in response to demyelination in vivo.Microglial malfunction: the third rail in the development of Alzheimer's disease.C1q-induced LRP1B and GPR6 proteins expressed early in Alzheimer disease mouse models, are essential for the C1q-mediated protection against amyloid-β neurotoxicity.The triggering receptor expressed on myeloid cells 2: "TREM-ming" the inflammatory component associated with Alzheimer's diseaseAlzheimer's disease risk gene CD33 inhibits microglial uptake of amyloid beta.Transcriptome Analysis on Monocytes from Patients with Neovascular Age-Related Macular Degeneration.Expression of the phagocytosis-essential protein TREM2 is down-regulated by an aluminum-induced miRNA-34a in a murine microglial cell lineDisease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease.Microglial activatory (immunoreceptor tyrosine-based activation motif)- and inhibitory (immunoreceptor tyrosine-based inhibition motif)-signaling receptors for recognition of the neuronal glycocalyx.TREM2 in Alzheimer's disease.Alzheimer's disease risk alleles in TREM2 illuminate innate immunity in Alzheimer's disease.The innate immune system in Alzheimer's disease.Innate immune activation in neurodegenerative disease.TYROBP in Alzheimer's disease.The Role of TREM2 in Alzheimer's Disease and Other Neurological Disorders.Innate immunity in Alzheimer's disease.TREM2 in Neurodegenerative Diseases.The Triggering Receptor Expressed on Myeloid Cells 2: A Molecular Link of Neuroinflammation and Neurodegenerative Diseases
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P2860
Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: implications for vaccine-based therapies for Alzheimer's disease.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Dual induction of TREM2 and to ...... apies for Alzheimer's disease.
@ast
Dual induction of TREM2 and to ...... apies for Alzheimer's disease.
@en
type
label
Dual induction of TREM2 and to ...... apies for Alzheimer's disease.
@ast
Dual induction of TREM2 and to ...... apies for Alzheimer's disease.
@en
prefLabel
Dual induction of TREM2 and to ...... apies for Alzheimer's disease.
@ast
Dual induction of TREM2 and to ...... apies for Alzheimer's disease.
@en
P2093
P2860
P50
P356
P1433
P1476
Dual induction of TREM2 and to ...... apies for Alzheimer's disease.
@en
P2093
Angie E Garcia
Anna K Stalder
J Cameron Thrash
Jonathan M Doose
Katherine M Lo
Monica J Carson
P2860
P304
P356
10.1042/AN20100010
P577
2010-07-12T00:00:00Z