Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: implications for vaccine-based therapies for Alzheimer's disease. - Test2 - elhamkhani - TriplyDB

Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: implications for vaccine-based therapies for Alzheimer's disease.

Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: implications for vaccine-based therapies for Alzheimer's disease.

http://www.wikidata.org/entity/Q33999537

about

Variant of TREM2 Associated with the Risk of Alzheimer's Disease Genetics ignite focus on microglial inflammation in Alzheimer's disease Osteoimmunology: Major and Costimulatory Pathway Expression Associated with Chronic Inflammatory Induced Bone Loss Functional involvement of γ-secretase in signaling of the triggering receptor expressed on myeloid cells-2 (TREM2).Targeting neuroinflammation in Alzheimer's disease Temporal-logic analysis of microglial phenotypic conversion with exposure to amyloid-β.Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2.Harnessing pain heterogeneity and RNA transcriptome to identify blood-based pain biomarkers: a novel correlational study design and bioinformatics approach in a graded chronic constriction injury model.Differentiation of mouse bone marrow derived stem cells toward microglia-like cells.The rare TREM2 R47H variant exerts only a modest effect on Alzheimer disease risk.Upregulation of TREM2 ameliorates neuropathology and rescues spatial cognitive impairment in a transgenic mouse model of Alzheimer's disease Attenuated inflammatory response in triggering receptor expressed on myeloid cells 2 (TREM2) knock-out mice following stroke.Frontobasal gray matter loss is associated with the TREM2 p.R47H variant A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model Development of a culture system to induce microglia-like cells from haematopoietic cells.The evolving biology of microglia in Alzheimer's disease.ProphNet: a generic prioritization method through propagation of information Different mechanisms of apolipoprotein E isoform-dependent modulation of prostaglandin E2 production and triggering receptor expressed on myeloid cells 2 (TREM2) expression after innate immune activation of microglia.TREM2 Protein Expression Changes Correlate with Alzheimer's Disease Neurodegenerative Pathologies in Post-Mortem Temporal Cortices RNA-sequencing reveals transcriptional up-regulation of Trem2 in response to bexarotene treatment.A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology.The triggering receptor expressed on myeloid cells 2 (TREM2) is associated with enhanced inflammation, neuropathological lesions and increased risk for Alzheimer's dementia TREM2 regulates microglial cell activation in response to demyelination in vivo.Microglial malfunction: the third rail in the development of Alzheimer's disease.C1q-induced LRP1B and GPR6 proteins expressed early in Alzheimer disease mouse models, are essential for the C1q-mediated protection against amyloid-β neurotoxicity.The triggering receptor expressed on myeloid cells 2: "TREM-ming" the inflammatory component associated with Alzheimer's disease Alzheimer's disease risk gene CD33 inhibits microglial uptake of amyloid beta.Transcriptome Analysis on Monocytes from Patients with Neovascular Age-Related Macular Degeneration.Expression of the phagocytosis-essential protein TREM2 is down-regulated by an aluminum-induced miRNA-34a in a murine microglial cell line Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease.Microglial activatory (immunoreceptor tyrosine-based activation motif)- and inhibitory (immunoreceptor tyrosine-based inhibition motif)-signaling receptors for recognition of the neuronal glycocalyx.TREM2 in Alzheimer's disease.Alzheimer's disease risk alleles in TREM2 illuminate innate immunity in Alzheimer's disease.The innate immune system in Alzheimer's disease.Innate immune activation in neurodegenerative disease.TYROBP in Alzheimer's disease.The Role of TREM2 in Alzheimer's Disease and Other Neurological Disorders.Innate immunity in Alzheimer's disease.TREM2 in Neurodegenerative Diseases.The Triggering Receptor Expressed on Myeloid Cells 2: A Molecular Link of Neuroinflammation and Neurodegenerative Diseases

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Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: implications for vaccine-based therapies for Alzheimer's disease.

http://www.wikidata.org/entity/Q33999537

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2010 nî lūn-bûn

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2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հուլիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Dual induction of TREM2 and to ...... apies for Alzheimer's disease.

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Dual induction of TREM2 and to ...... apies for Alzheimer's disease.

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Dual induction of TREM2 and to ...... apies for Alzheimer's disease.

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Dual induction of TREM2 and to ...... apies for Alzheimer's disease.

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Dual induction of TREM2 and to ...... apies for Alzheimer's disease.

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Dual induction of TREM2 and to ...... apies for Alzheimer's disease.

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Dual induction of TREM2 and to ...... apies for Alzheimer's disease.

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Angie E Garcia

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Anna K Stalder

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J Cameron Thrash

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Jonathan M Doose

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Katherine M Lo

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Monica J Carson

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P2860

A DAP12-mediated pathway regulates expression of CC chemokine receptor 7 and maturation of human dendritic cells

P2X7-dependent release of interleukin-1beta and nociception in the spinal cord following lipopolysaccharide

CNS immune privilege: hiding in plain sight.

Identification of soluble TREM-2 in the cerebrospinal fluid and its association with multiple sclerosis and CNS inflammation

Neuropsychological tests and functional nuclear neuroimaging provide evidence of subclinical impairment in Nasu-Hakola disease heterozygotes

Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood

Control of microglial neurotoxicity by the fractalkine receptor

Rett syndrome and other autism spectrum disorders--brain diseases of immune malfunction?

Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease.

TREM2-transduced myeloid precursors mediate nervous tissue debris clearance and facilitate recovery in an animal model of multiple sclerosis.

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10.1042/AN20100010

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3

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2

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Benoit Melchior

Matthias Staufenbiel

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2010-07-12T00:00:00Z

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45272548

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20640189

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Alzheimer's disease

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2905103

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