Bumetanide, an NKCC1 antagonist, does not prevent formation of epileptogenic focus but blocks epileptic focus seizures in immature rat hippocampus.
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Expanding Spectrum of Sodium Potassium Chloride Co-transporters in the Pathophysiology of DiseasesCurrent view on the functional regulation of the neuronal K(+)-Cl(-) cotransporter KCC2Age- and sex-dependent susceptibility to phenobarbital-resistant neonatal seizures: role of chloride co-transportersThe Subiculum: A Potential Site of Ictogenesis in a Neonatal Seizure Model.Neuronal chloride accumulation and excitatory GABA underlie aggravation of neonatal epileptiform activities by phenobarbital.Temporal coding at the immature depolarizing GABAergic synapse.Failure of the Nemo Trial: Bumetanide Is a Promising Agent to Treat Many Brain Disorders but Not Newborn SeizuresProgressive NKCC1-dependent neuronal chloride accumulation during neonatal seizures.Altered GABA signaling in early life epilepsies.Acute and chronic efficacy of bumetanide in an in vitro model of posttraumatic epileptogenesis.Carts, Horses, and Push-Pull Regulation of EGABA in Neonatal SeizuresTraumatic alterations in GABA signaling disrupt hippocampal network activity in the developing brain.GABAergic depolarization during early cortical development and implications for anticonvulsive therapy in neonates.Excitatory action of GABA on immature neurons is not due to absence of ketone bodies metabolites or other energy substrates.Spatial and temporal dynamics in the ionic driving force for GABA(A) receptors.GABAergic synchronization in the limbic system and its role in the generation of epileptiform activity.Is it safe to use a diuretic to treat seizures early in development ?Blocking seizures with the diuretic bumetanide: promises and pitfalls.Depolarizing GABA and developmental epilepsies.GABAergic Synchronization in Epilepsy.Enhanced Synaptic Activity and Epileptiform Events in the Embryonic KCC2 Deficient Hippocampus.Phenobarbital but Not Diazepam Reduces AMPA/kainate Receptor Mediated Currents and Exerts Opposite Actions on Initial Seizures in the Neonatal Rat Hippocampus.Chloride's Exciting Role in Neonatal Seizures Suggests Novel Therapeutic Approach.Knocking down of the KCC2 in rat hippocampal neurons increases intracellular chloride concentration and compromises neuronal survival.Investigating the stress attenuating potential of furosemide in immobilization and electric foot-shock stress models in mice.Similar nicotinic excitability responses across the developing hippocampal formation are regulated by small conductance calcium-activated potassium channels.Genetic and pharmacological modulation of giant depolarizing potentials in the neonatal hippocampus associates with increased seizure susceptibility.Resolution of headache and papilledema in idiopathic intracranial hypertension associated with inhibition of Na+-K+-2Cl- cotransport.
P2860
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P2860
Bumetanide, an NKCC1 antagonist, does not prevent formation of epileptogenic focus but blocks epileptic focus seizures in immature rat hippocampus.
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2009 nî lūn-bûn
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2009 թուականի Մարտին հրատարակուած գիտական յօդուած
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2009 թվականի մարտին հրատարակված գիտական հոդված
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2009年の論文
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2009年論文
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2009年論文
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2009年論文
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2009年論文
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2009年論文
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2009年论文
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name
Bumetanide, an NKCC1 antagonis ...... s in immature rat hippocampus.
@ast
Bumetanide, an NKCC1 antagonis ...... s in immature rat hippocampus.
@en
Bumetanide, an NKCC1 antagonis ...... s in immature rat hippocampus.
@nl
type
label
Bumetanide, an NKCC1 antagonis ...... s in immature rat hippocampus.
@ast
Bumetanide, an NKCC1 antagonis ...... s in immature rat hippocampus.
@en
Bumetanide, an NKCC1 antagonis ...... s in immature rat hippocampus.
@nl
prefLabel
Bumetanide, an NKCC1 antagonis ...... s in immature rat hippocampus.
@ast
Bumetanide, an NKCC1 antagonis ...... s in immature rat hippocampus.
@en
Bumetanide, an NKCC1 antagonis ...... s in immature rat hippocampus.
@nl
P2860
P356
P1476
Bumetanide, an NKCC1 antagonis ...... s in immature rat hippocampus.
@en
P2093
Romain Nardou
P2860
P304
P356
10.1152/JN.90761.2008
P407
P577
2009-03-18T00:00:00Z