Preparation of well-defined antibody-drug conjugates through glycan remodeling and strain-promoted azide-alkyne cycloadditions.
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Site-Specifically Labeled Immunoconjugates for Molecular Imaging--Part 1: Cysteine Residues and GlycansA noncanonical function of sortase enables site-specific conjugation of small molecules to lysine residues in proteinsSite-specific antibody-drug conjugates: the nexus of bioorthogonal chemistry, protein engineering, and drug developmentMethods to Make Homogenous Antibody Drug Conjugates.Microscale screening of antibody libraries as maytansinoid antibody-drug conjugates.A PEGylated photocleavable auxiliary mediates the sequential enzymatic glycosylation and native chemical ligation of peptides.Improved variants of SrtA for site-specific conjugation on antibodies and proteins with high efficiencyEmerging formats for next-generation antibody drug conjugates.Introducing Glycolinkers for the Functionalization of Cytotoxic Drugs and Applications in Antibody-Drug Conjugation Chemistry.Structurally Defined αMHC-II Nanobody-Drug Conjugates: A Therapeutic and Imaging System for B-Cell Lymphoma.Metabolic Glycoengineering with N-Acyl Side Chain Modified Mannosamines.Strategies and challenges for the next generation of antibody-drug conjugates.Improving Antibody-Based Cancer Therapeutics Through Glycan Engineering.Real-Time Analysis on Drug-Antibody Ratio of Antibody-Drug Conjugates for Synthesis, Process Optimization, and Quality ControlChemoenzymatic strategy for the synthesis of site-specifically labeled immunoconjugates for multimodal PET and optical imaging.Harnessing a catalytic lysine residue for the one-step preparation of homogeneous antibody-drug conjugatesCrystallizable Fragment Glycoengineering for Therapeutic Antibodies Development.CD22 Ligands on a Natural N-Glycan Scaffold Efficiently Deliver Toxins to B-Lymphoma Cells.Improving theranostics in pancreatic cancer.Straightforward Glycoengineering Approach to Site-Specific Antibody-Pyrrolobenzodiazepine Conjugates.Chemoenzymatic synthesis of glycoengineered IgG antibodies and glycosite-specific antibody-drug conjugates.One-pot N-glycosylation remodeling of IgG with non-natural sialylglycopeptides enables glycosite-specific and dual-payload antibody-drug conjugates."Clicking" gene therapeutics: A successful union of chemistry and biomedicine for new solutions.Site-Specific Antibody Conjugation for ADC and Beyond.A flow platform for degradation-free CuAAC bioconjugationConstruction of homogeneous antibody-drug conjugates using site-selective protein chemistryAsking more from metabolic oligosaccharide engineeringImproving Immunotherapy Through Glycodesign
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P2860
Preparation of well-defined antibody-drug conjugates through glycan remodeling and strain-promoted azide-alkyne cycloadditions.
description
2014 nî lūn-bûn
@nan
2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Preparation of well-defined an ...... d azide-alkyne cycloadditions.
@ast
Preparation of well-defined an ...... d azide-alkyne cycloadditions.
@en
Preparation of well-defined an ...... d azide-alkyne cycloadditions.
@nl
type
label
Preparation of well-defined an ...... d azide-alkyne cycloadditions.
@ast
Preparation of well-defined an ...... d azide-alkyne cycloadditions.
@en
Preparation of well-defined an ...... d azide-alkyne cycloadditions.
@nl
prefLabel
Preparation of well-defined an ...... d azide-alkyne cycloadditions.
@ast
Preparation of well-defined an ...... d azide-alkyne cycloadditions.
@en
Preparation of well-defined an ...... d azide-alkyne cycloadditions.
@nl
P2860
P356
P1476
Preparation of well-defined an ...... d azide-alkyne cycloadditions.
@en
P2093
P2860
P304
P356
10.1002/ANIE.201402606
P407
P577
2014-05-23T00:00:00Z