Lysine-specific demethylase 2B (KDM2B)-let-7-enhancer of zester homolog 2 (EZH2) pathway regulates cell cycle progression and senescence in primary cells. - Test2 - elhamkhani - TriplyDB

Lysine-specific demethylase 2B (KDM2B)-let-7-enhancer of zester homolog 2 (EZH2) pathway regulates cell cycle progression and senescence in primary cells.

Lysine-specific demethylase 2B (KDM2B)-let-7-enhancer of zester homolog 2 (EZH2) pathway regulates cell cycle progression and senescence in primary cells.

http://www.wikidata.org/entity/Q34027680

about

The emerging role of histone lysine demethylases in prostate cancer Hypoxia-Inducible Histone Lysine Demethylases: Impact on the Aging Process and Age-Related Diseases Noncoding RNA control of cellular senescence EZH2 in Bladder Cancer, a Promising Therapeutic Target Identification of senescence-associated circular RNAs (SAC-RNAs) reveals senescence suppressor CircPVT1 Histone demethylase KDM2B upregulates histone methyltransferase EZH2 expression and contributes to the progression of ovarian cancer in vitro and in vivo Functional and therapeutic significance of EZH2 in urological cancers KDM2B promotes pancreatic cancer via Polycomb-dependent and -independent transcriptional programs.Identification of microRNA-mRNA functional interactions in UVB-induced senescence of human diploid fibroblasts Integrative analysis of porcine microRNAome during skeletal muscle development.The KDM2B- let-7b -EZH2 axis in myelodysplastic syndromes as a target for combined epigenetic therapy MiR-101 induces senescence and prevents apoptosis in the background of DNA damage in MCF7 cells.MK3 modulation affects BMI1-dependent and independent cell cycle check-points.Regulation of senescence by microRNA biogenesis factors MicroRNAs in age-related diseases.Histone demethylase KDM2B regulates lineage commitment in normal and malignant hematopoiesis.Mutant p53 induces EZH2 expression and promotes epithelial-mesenchymal transition by disrupting p68-Drosha complex assembly and attenuating miR-26a processing Ubiquitination-mediated degradation of cell cycle-related proteins by F-box proteins miRNA let-7b modulates macrophage polarization and enhances tumor-associated macrophages to promote angiogenesis and mobility in prostate cancer.Role of EZH2 in the growth of prostate cancer stem cells isolated from LNCaP cells.Knockdown of fbxl10/kdm2bb rescues chd7 morphant phenotype in a zebrafish model of CHARGE syndrome Epigenetic reprogramming in cancer.Cellular senescence mediated by p16INK4A-coupled miRNA pathways.Jumonji domain-containing protein 2B silencing induces DNA damage response via STAT3 pathway in colorectal cancer.EZH2 mediates lidamycin-induced cellular senescence through regulating p21 expression in human colon cancer cells.SET for life: biochemical activities and biological functions of SET domain-containing proteins Non-coding RNAs and EZH2 interactions in cancer: long and short tales from the transcriptome.Histone lysine methylation dynamics: establishment, regulation, and biological impact The roles of ncRNAs and histone-modifiers in regulating breast cancer stem cells.MicroRNA regulation of F-box proteins and its role in cancer.Curcumin Inhibits LIN-28A through the Activation of miRNA-98 in the Lung Cancer Cell Line A549.JMJD1A promotes tumorigenesis and forms a feedback loop with EZH2/let-7c in NSCLC cells.Lysine-specific histone demethylases in normal and malignant hematopoiesis.The Histone Demethylase FBXL10 Regulates the Proliferation of Spermatogonia and Ensures Long-Term Sustainable Spermatogenesis in Mice.EZH2 regulates neuroepithelium structure and neuroblast proliferation by repressing p21.Regulation of p53 and Rb links the alternative NF-κB pathway to EZH2 expression and cell senescence.Epigenetic control and cancer: the potential of histone demethylases as therapeutic targets.Alternative Splicing of EZH2 pre-mRNA by SF3B3 Contributes to the Tumorigenic Potential of Renal Cancer.F-box proteins in epigenetic regulation of cancer.Targeting glioma stem-like cell survival and chemo-resistance through inhibition of lysine-specific histone demethylase KDM2B.

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P2860

Lysine-specific demethylase 2B (KDM2B)-let-7-enhancer of zester homolog 2 (EZH2) pathway regulates cell cycle progression and senescence in primary cells.

http://www.wikidata.org/entity/Q34027680

description

2011 nî lūn-bûn

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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հուլիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

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2011年論文

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2011年论文

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name

Lysine-specific demethylase 2B ...... d senescence in primary cells.

@ast

Lysine-specific demethylase 2B ...... d senescence in primary cells.

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Lysine-specific demethylase 2B

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type

label

Lysine-specific demethylase 2B ...... d senescence in primary cells.

@ast

Lysine-specific demethylase 2B ...... d senescence in primary cells.

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Lysine-specific demethylase 2B

@nl

prefLabel

Lysine-specific demethylase 2B ...... d senescence in primary cells.

@ast

Lysine-specific demethylase 2B ...... d senescence in primary cells.

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Lysine-specific demethylase 2B

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JBC.M111.257667

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Journal of Biological Chemistry

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Lysine-specific demethylase 2B ...... nd senescence in primary cells

@en

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Alexandros Tzatsos

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Nabeel Bardeesy

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Polina Paskaleva

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Stephania Lymperi

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Svetlana Stoykova

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Zhao Chen

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P2860

Polycomb group and SCF ubiquitin ligases are found in a novel BCOR complex that is recruited to BCL6 targets

CpG islands recruit a histone H3 lysine 36 demethylase

BCOR regulates mesenchymal stem cell function by epigenetic mechanisms

Fbxl10/Kdm2b deficiency accelerates neural progenitor cell death and leads to exencephaly

Senescence of activated stellate cells limits liver fibrosis

let-7 Overexpression leads to an increased fraction of cells in G2/M, direct down-regulation of Cdc34, and stabilization of Wee1 kinase in primary fibroblasts

Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

let-7 regulates self renewal and tumorigenicity of breast cancer cells

Facile means for quantifying microRNA expression by real-time PCR

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33061-33069

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10.1074/JBC.M111.257667

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38

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286

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Gianmarco Contino

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2011-07-11T00:00:00Z

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21757686

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3190920

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