Dilated cardiomyopathy in mice deficient for the lysosomal cysteine peptidase cathepsin L. - Test2 - elhamkhani - TriplyDB

Dilated cardiomyopathy in mice deficient for the lysosomal cysteine peptidase cathepsin L.

Dilated cardiomyopathy in mice deficient for the lysosomal cysteine peptidase cathepsin L.

http://www.wikidata.org/entity/Q34028619

about

ABCA5 resides in lysosomes, and ABCA5 knockout mice develop lysosomal disease-like symptoms Transcription factor MITF regulates cardiac growth and hypertrophy Deficiency for the cysteine protease cathepsin L impairs Myc-induced tumorigenesis in a mouse model of pancreatic neuroendocrine cancer Lysosomal integral membrane protein 2 is a novel component of the cardiac intercalated disc and vital for load-induced cardiac myocyte hypertrophy Mitophagy and heart failure Presence of anti-cystatin C-positive dendritic cells or macrophages and localization of cysteine proteases in the apical bud of the enamel organ in the rat incisor Cathepsin L colocalizes with chromogranin a in chromaffin vesicles to generate active peptides Cathepsin L inhibition suppresses drug resistance in vitro and in vivo: a putative mechanism.Autophagy and the ubiquitin-proteasome system in cardiac dysfunction.Do molecular signals from the conceptus influence endometrium decidualization in rodents?Mechanism of diastolic stiffening of the failing myocardium and its prevention by angiotensin receptor and calcium channel blockers.Disrupted in renal carcinoma 2 (DIRC2), a novel transporter of the lysosomal membrane, is proteolytically processed by cathepsin L.Distinct roles for cysteine cathepsin genes in multistage tumorigenesis B-cell lymphopoiesis is regulated by cathepsin L.Cathepsin L stabilizes the histone modification landscape on the Y chromosome and pericentromeric heterochromatin.Thyroid functions of mouse cathepsins B, K, and L.Lysosomal protein turnover contributes to the acquisition of TGFβ-1 induced invasive properties of mammary cancer cells.Protective role of cathepsin L in mouse skin carcinogenesis.Family C1 cysteine proteases: biological diversity or redundancy?Toward computer-based cleavage site prediction of cysteine endopeptidases.Cathepsin L in secretory vesicles functions as a prohormone-processing enzyme for production of the enkephalin peptide neurotransmitter.Cathepsin-L, a key molecule in the pathogenesis of drug-induced and I-cell disease-mediated gingival overgrowth: a study with cathepsin-L-deficient mice.Cysteinyl cathepsins: multifunctional enzymes in cardiovascular disease.Cathepsin L targeting in cancer treatment.Cathepsin L acutely alters microvessel integrity within the neurovascular unit during focal cerebral ischemia.Genes and environment: novel, functional polymorphism in the human cathepsin L (CTSL1) promoter disrupts a xenobiotic response element (XRE) to alter transcription and blood pressure.Cysteine cathepsins in the immune response.Superoxide-dependent cathepsin activation is associated with hypertensive myocardial remodeling and represents a target for angiotensin II type 1 receptor blocker treatment.Cathepsin-L ameliorates cardiac hypertrophy through activation of the autophagy-lysosomal dependent protein processing pathways.Cysteine cathepsin non-inhibitory binding partners: modulating intracellular trafficking and function.Cysteine proteases: destruction ability versus immunomodulation capacity in immune cells.Proteases for processing proneuropeptides into peptide neurotransmitters and hormones.Cysteine cathepsin S as an immunomodulatory target: present and future trends.Cathepsin S-mediated fibroblast trans-differentiation contributes to left ventricular remodelling after myocardial infarction.Usefulness of serum cathepsin L as an independent biomarker in patients with coronary heart disease.Cathepsins mediate tumor metastasis.Specialized roles for cysteine cathepsins in health and disease.Cysteine cathepsins and their potential in clinical therapy and biomarker discovery.Review of molecular and mechanical interactions in the aortic valve and aorta: implications for the shared pathogenesis of aortic valve disease and aortopathy.Starvation response in mouse liver shows strong correlation with life-span-prolonging processes.

P2860

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P2860

Dilated cardiomyopathy in mice deficient for the lysosomal cysteine peptidase cathepsin L.

http://www.wikidata.org/entity/Q34028619

description

2002 nî lūn-bûn

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2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2002 թվականի ապրիլին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

Dilated cardiomyopathy in mice ...... ysteine peptidase cathepsin L.

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Dilated cardiomyopathy in mice ...... ysteine peptidase cathepsin L.

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Dilated cardiomyopathy in mice ...... ysteine peptidase cathepsin L.

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type

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Dilated cardiomyopathy in mice ...... ysteine peptidase cathepsin L.

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Dilated cardiomyopathy in mice ...... ysteine peptidase cathepsin L.

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Dilated cardiomyopathy in mice ...... ysteine peptidase cathepsin L.

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Dilated cardiomyopathy in mice ...... ysteine peptidase cathepsin L.

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Dilated cardiomyopathy in mice ...... ysteine peptidase cathepsin L.

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Dilated cardiomyopathy in mice ...... ysteine peptidase cathepsin L.

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Proceedings of the National Academy of Sciences of the United States of America

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Dilated cardiomyopathy in mice ...... ysteine peptidase cathepsin L.

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P2093

Christoph Peters

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Desmond J Tobin

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Ivonne Petermann

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Jörg Stypmann

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Kerstin Gläser

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Rainer Matthias

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Thomas Reinheckel

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Wera Roth

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Wolfgang Schmahl

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P2860

Neonatal cardiomyopathy in mice homozygous for the Arg403Gln mutation in the alpha cardiac myosin heavy chain gene.

Constitutively active AMP kinase mutations cause glycogen storage disease mimicking hypertrophic cardiomyopathy

Actin mutations in dilated cardiomyopathy, a heritable form of heart failure

Secreted cathepsin L generates endostatin from collagen XVIII

Mutations in the human delta-sarcoglycan gene in familial and sporadic dilated cardiomyopathy

Mutations in sarcomere protein genes as a cause of dilated cardiomyopathy

Disruption of the sarcoglycan-sarcospan complex in vascular smooth muscle: a novel mechanism for cardiomyopathy and muscular dystrophy

The genetic basis for cardiomyopathy: from mutation identification to mechanistic paradigms

Emerging roles for cysteine proteases in human biology

The inhibition of macrophage protein turnover by a selective inhibitor of thiol proteinases

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6234-6239

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10.1073/PNAS.092637699

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9

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99

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Günter Breithardt

Wilhelm Haverkamp

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2002-04-23T00:00:00Z

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11396488

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11972068

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122932

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