Core-binding factor β increases the affinity between human Cullin 5 and HIV-1 Vif within an E3 ligase complex
about
Multiple APOBEC3 restriction factors for HIV-1 and one Vif to rule them allMultimeric Complexes among Ankyrin-Repeat and SOCS-box Protein 9 (ASB9), ElonginBC, and Cullin 5: Insights into the Structure and Assembly of ECS-type Cullin-RING E3 Ubiquitin LigasesCore binding factor beta plays a critical role by facilitating the assembly of the Vif-cullin 5 E3 ubiquitin ligase.Evolutionarily conserved requirement for core binding factor beta in the assembly of the human immunodeficiency virus/simian immunodeficiency virus Vif-cullin 5-RING E3 ubiquitin ligase.Core-binding factor subunit beta is not required for non-primate lentiviral Vif-mediated APOBEC3 degradation.Requirement of HIV-1 Vif C-terminus for Vif-CBF-β interaction and assembly of CUL5-containing E3 ligaseBiophysical studies on interactions and assembly of full-size E3 ubiquitin ligase: suppressor of cytokine signaling 2 (SOCS2)-elongin BC-cullin 5-ring box protein 2 (RBX2).Temporal proteomic analysis of HIV infection reveals remodelling of the host phosphoproteome by lentiviral Vif variantsAPOBEC3G-Mediated G-to-A Hypermutation of the HIV-1 Genome: The Missing Link in Antiviral Molecular MechanismsHIV-1 Vif N-terminal motif is required for recruitment of Cul5 to suppress APOBEC3.Dispersed and conserved hydrophobic residues of HIV-1 Vif are essential for CBFβ recruitment and A3G suppression.Identification of a tripartite interaction between the N-terminus of HIV-1 Vif and CBFβ that is critical for Vif functionCBFβ enhances de novo protein biosynthesis of its binding partners HIV-1 Vif and RUNX1 and potentiates the Vif-induced degradation of APOBEC3G.ITC analysis of ligand binding to preQ₁ riboswitches.Crystal Structure of the Cul2-Rbx1-EloBC-VHL Ubiquitin Ligase Complex.Clues for two-step virion infectivity factor regulation by core binding factor beta.Determinants of efficient degradation of APOBEC3 restriction factors by HIV-1 Vif.
P2860
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P2860
Core-binding factor β increases the affinity between human Cullin 5 and HIV-1 Vif within an E3 ligase complex
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2012 nî lūn-bûn
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2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
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2012年論文
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2012年論文
@zh-hant
2012年論文
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2012年論文
@zh-mo
2012年論文
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2012年论文
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name
Core-binding factor β increase ...... if within an E3 ligase complex
@ast
Core-binding factor β increase ...... if within an E3 ligase complex
@en
Core-binding factor β increase ...... if within an E3 ligase complex
@nl
type
label
Core-binding factor β increase ...... if within an E3 ligase complex
@ast
Core-binding factor β increase ...... if within an E3 ligase complex
@en
Core-binding factor β increase ...... if within an E3 ligase complex
@nl
prefLabel
Core-binding factor β increase ...... if within an E3 ligase complex
@ast
Core-binding factor β increase ...... if within an E3 ligase complex
@en
Core-binding factor β increase ...... if within an E3 ligase complex
@nl
P2093
P2860
P356
P1433
P1476
Core-binding factor β increase ...... if within an E3 ligase complex
@en
P2093
Geoffrey M Lippa
Ivan A Belashov
Jason D Salter
Joseph E Wedekind
P2860
P304
P356
10.1021/BI301244Z
P407
P577
2012-10-25T00:00:00Z