Loss of function of the tumor suppressor DKC1 perturbs p27 translation control and contributes to pituitary tumorigenesis. - Test2 - elhamkhani - TriplyDB

Loss of function of the tumor suppressor DKC1 perturbs p27 translation control and contributes to pituitary tumorigenesis.

Loss of function of the tumor suppressor DKC1 perturbs p27 translation control and contributes to pituitary tumorigenesis.

http://www.wikidata.org/entity/Q34035639

about

Cap-Independent Translational Control of Carcinogenesis Could the eIF2α-Independent Translation Be the Achilles Heel of Cancer?Pituitary adenomas: historical perspective, surgical management and future directions The molecular pathogenesis of pituitary adenomas: an update Small RNAs with big implications: new insights into H/ACA snoRNA function and their role in human disease Inhibition of human dyskerin as a new approach to target ribosome biogenesis Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning Loss of Drosophila pseudouridine synthase triggers apoptosis-induced proliferation and promotes cell-nonautonomous EMT.Specialized ribosomes: a new frontier in gene regulation and organismal biology.New frontiers in translational control of the cancer genome The cancerous translation apparatus Dyskerin overexpression in human hepatocellular carcinoma is associated with advanced clinical stage and poor patient prognosis Ribosomopathies: mechanisms of disease.Dyskerin is required for tumor cell growth through mechanisms that are independent of its role in telomerase and only partially related to its function in precursor rRNA processing.RNA regulons in Hox 5' UTRs confer ribosome specificity to gene regulation.Inactivation of X-linked tumor suppressor genes in human cancer.Far upstream element binding protein 1 activates translation of p27Kip1 mRNA through its internal ribosomal entry site CUG-binding protein represses translation of p27Kip1 mRNA through its internal ribosomal entry site rRNA pseudouridylation defects affect ribosomal ligand binding and translational fidelity from yeast to human cells.Reversible induction of translational isoforms of p53 in glucose deprivation.A mass spectrometry-based method for comprehensive quantitative determination of post-transcriptional RNA modifications: the complete chemical structure of Schizosaccharomyces pombe ribosomal RNAs Translational control in cancer etiology.Small molecule inhibitors of IRES-mediated translation.H/ACA small RNA dysfunctions in disease reveal key roles for noncoding RNA modifications in hematopoietic stem cell differentiation.A ribosome-related signature in peripheral blood CLL B cells is linked to reduced survival following treatment.The molecular pathogenesis of corticotroph tumours.Translational control in cellular and developmental processes.RNA binding protein/RNA element interactions and the control of translation Regulation of snoRNAs in cancer: close encounters with interferon.Translation factors and ribosomal proteins control tumor onset and progression: how?p27 and leukemia: cell cycle and beyond.H/ACA Box Small Nucleolar RNA 7A Promotes the Self-Renewal of Human Umbilical Cord Mesenchymal Stem Cells.Etiology and pathogenesis of the cohesinopathies.Transcriptome-wide dynamics of RNA pseudouridylation.Requirement of rRNA methylation for 80S ribosome assembly on a cohort of cellular internal ribosome entry sites.Severity of X-linked dyskeratosis congenita (DKCX) cellular defects is not directly related to dyskerin (DKC1) activity in ribosomal RNA biogenesis or mRNA translation.Dyskerin depletion increases VEGF mRNA internal ribosome entry site-mediated translation.Investigating Myc-dependent translational regulation in normal and cancer cells.RNA Pseudouridylation in Physiology and Medicine: For Better and for Worse.Tuning the ribosome: The influence of rRNA modification on eukaryotic ribosome biogenesis and function.

P2860

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P2860

Loss of function of the tumor suppressor DKC1 perturbs p27 translation control and contributes to pituitary tumorigenesis.

http://www.wikidata.org/entity/Q34035639

description

2010 nî lūn-bûn

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2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Loss of function of the tumor ...... es to pituitary tumorigenesis.

@ast

Loss of function of the tumor ...... es to pituitary tumorigenesis.

@en

Loss of function of the tumor ...... es to pituitary tumorigenesis.

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type

label

Loss of function of the tumor ...... es to pituitary tumorigenesis.

@ast

Loss of function of the tumor ...... es to pituitary tumorigenesis.

@en

Loss of function of the tumor ...... es to pituitary tumorigenesis.

@nl

prefLabel

Loss of function of the tumor ...... es to pituitary tumorigenesis.

@ast

Loss of function of the tumor ...... es to pituitary tumorigenesis.

@en

Loss of function of the tumor ...... es to pituitary tumorigenesis.

@nl

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Loss of function of the tumor ...... es to pituitary tumorigenesis.

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Cristian Bellodi

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Davide Ruggero

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Guang Peng

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Lorenzo Montanaro

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Olya Krasnykh

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P2860

Implication of snoRNA U50 in human breast cancer

Skp2 is required for survival of aberrantly proliferating Rb1-deficient cells and for tumorigenesis in Rb1+/- mice

Acromegaly pathogenesis and treatment

Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humans

Regulation of translation initiation in eukaryotes: mechanisms and biological targets

Cell cycle-dependent translation of p27 involves a responsive element in its 5'-UTR that overlaps with a uORF

Mouse dyskerin mutations affect accumulation of telomerase RNA and small nucleolar RNA, telomerase activity, and ribosomal RNA processing

Isolation and characterization of a pituitary tumor-transforming gene (PTTG)

Translational control in stress and apoptosis

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

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Marily Theodoropoulou

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2010-06-29T00:00:00Z

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20587522

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