Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death. - Test2 - elhamkhani - TriplyDB

Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death.

Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death.

http://www.wikidata.org/entity/Q34043163

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The complex relationships between microglia, alpha-synuclein, and LRRK2 in Parkinson's disease Converging roles of ion channels, calcium, metabolic stress, and activity pattern of Substantia nigra dopaminergic neurons in health and Parkinson's disease Nanoparticles restore lysosomal acidification defects: Implications for Parkinson and other lysosomal-related diseases.Autophagy and Mitochondrial Dysfunction in Tenon Fibroblasts from Exfoliation Glaucoma Patients.Integrated analysis of genetic, behavioral, and biochemical data implicates neural stem cell-induced changes in immunity, neurotransmission and mitochondrial function in Dementia with Lewy Body mice.Neuropathology of α-synuclein propagation and braak hypothesis.Targeting α-synuclein: Therapeutic options.Endocytic vesicle rupture is a conserved mechanism of cellular invasion by amyloid proteins.The Coordinated Action of Calcineurin and Cathepsin D Protects Against α-Synuclein Toxicity.Selective imaging of internalized proteopathic α-synuclein seeds in primary neurons reveals mechanistic insight into transmission of synucleinopathies.Editorial: Parkinson's disease: cell vulnerability and disease progression.Tunneling nanotubes spread fibrillar α-synuclein by intercellular trafficking of lysosomes.Individual Amino Acid Supplementation Can Improve Energy Metabolism and Decrease ROS Production in Neuronal Cells Overexpressing Alpha-Synuclein.Modulating the catalytic activity of AMPK has neuroprotective effects against α-synuclein toxicity.Resveratrol alleviates MPTP-induced motor impairments and pathological changes by autophagic degradation of α-synuclein via SIRT1-deacetylated LC3.Treadmill Exercise Attenuates α-Synuclein Levels by Promoting Mitochondrial Function and Autophagy Possibly via SIRT1 in the Chronic MPTP/P-Induced Mouse Model of Parkinson's Disease.Can Interactions Between α-Synuclein, Dopamine and Calcium Explain Selective Neurodegeneration in Parkinson's Disease?Pleiotropic Effects of Variants in Dementia Genes in Parkinson Disease.Alpha-synuclein A53T mutation is not frequent on a sample of Brazilian Parkinson's disease patients.

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P2860

Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death.

http://www.wikidata.org/entity/Q34043163

description

2014 nî lūn-bûn

@nan

2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի օգոստոսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death.

@ast

Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death.

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Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death.

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type

label

Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death.

@ast

Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death.

@en

Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death.

@nl

prefLabel

Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death.

@ast

Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death.

@en

Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death.

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FNANA.2014.00083

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Frontiers in Neuroanatomy

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Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death

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Mathieu Bourdenx

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P2860

Integral and associated lysosomal membrane proteins

Gaucher disease glucocerebrosidase and α-synuclein form a bidirectional pathogenic loop in synucleinopathies

The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy

Interplay of LRRK2 with chaperone-mediated autophagy

Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease

α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation

Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies

α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells.

Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease.

Regulation of neuronal survival factor MEF2D by chaperone-mediated autophagy

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83

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scholarly article

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10.3389/FNANA.2014.00083

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