The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors - Test2 - elhamkhani - TriplyDB

The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors

The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors

http://www.wikidata.org/entity/Q34064211

about

Targeting membrane-bound viral RNA synthesis reveals potent inhibition of diverse coronaviruses including the middle East respiratory syndrome virus Suppression of coronavirus replication by cyclophilin inhibitors Curing a viral infection by targeting the host: the example of cyclophilin inhibitors Recent developments in antiviral agents against enterovirus 71 infection NTCP and beyond: opening the door to unveil hepatitis B virus entry Functional protein microarray as molecular decathlete: a versatile player in clinical proteomics Coronaviruses and the human airway: a universal system for virus-host interaction studies Virus-host interactomics: new insights and opportunities for antiviral drug discovery Coronavirus replicase-reporter fusions provide quantitative analysis of replication and replication complex formation.Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities Immunosuppressive treatment combined with nucleoside analog is superior to nucleoside analog only in the treatment of severe thrombocytopenia in patients with cirrhosis associated with hepatitis B in China: A multicenter, observational study.Systems virology: host-directed approaches to viral pathogenesis and drug targeting.Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture.Microbial peptidyl-prolyl cis/trans isomerases (PPIases): virulence factors and potential alternative drug targets.Middle East respiratory syndrome coronavirus: another zoonotic betacoronavirus causing SARS-like disease MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatment Cyclosporin A and its analogs inhibit hepatitis B virus entry into cultured hepatocytes through targeting a membrane transporter, sodium taurocholate cotransporting polypeptide (NTCP).Identification of residues of SARS-CoV nsp1 that differentially affect inhibition of gene expression and antiviral signaling.A systematic analysis of host factors reveals a Med23-interferon-λ regulatory axis against herpes simplex virus type 1 replication.Genomic and proteomic analysis of Schizaphis graminum reveals cyclophilin proteins are involved in the transmission of cereal yellow dwarf virus Bioengineering and semisynthesis of an optimized cyclophilin inhibitor for treatment of chronic viral infection.Coronavirus nonstructural protein 1: Common and distinct functions in the regulation of host and viral gene expression.RNA sequencing-based analysis of the spleen transcriptome following infectious bronchitis virus infection of chickens selected for different mannose-binding lectin serum concentrations Genome-Wide Screen Reveals Valosin-Containing Protein Requirement for Coronavirus Exit from Endosomes.Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus Severe acute respiratory syndrome coronavirus nonstructural proteins 3, 4, and 6 induce double-membrane vesicles p53 down-regulates SARS coronavirus replication and is targeted by the SARS-unique domain and PLpro via E3 ubiquitin ligase RCHY1 Cell-based antiviral screening against coronaviruses: developing virus-specific and broad-spectrum inhibitors Human enterovirus 71 protein interaction network prompts antiviral drug repositioning.Cyclophilin involvement in the replication of hepatitis C virus and other viruses.Cyclophilins as modulators of viral replication.Antiviral drug discovery: broad-spectrum drugs from nature.Enhanced molecular dynamics sampling of drug target conformations.Host Factors in Coronavirus Replication.Proteomic analysis for Type I interferon antagonism of Japanese encephalitis virus NS5 protein.Cyclophilin inhibitors block arterivirus replication by interfering with viral RNA synthesis.Suppression of feline coronavirus replication in vitro by cyclosporin A.Evaluation of a Bead-Free Coimmunoprecipitation Technique for Identification of Virus-Host Protein Interactions Using High-Resolution Mass Spectrometry.Current landscape and future prospects of antiviral drugs derived from microbial products.Transgene expression in the genome of Middle East respiratory syndrome coronavirus based on a novel reverse genetics system utilizing Red-mediated recombination cloning.

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The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors

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2011 nî lūn-bûn

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2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2011 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年学术文章

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2011年学术文章

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JOURNAL.PPAT.1002331

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The SARS-coronavirus-host inte ...... for pan-coronavirus inhibitors

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Albrecht von Brunn

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Christel Schwegmann-Wessels

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Daniela Niemeyer

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Ekatarina von Dall'Armi

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Frank Schwarz

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P2860

Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase

Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300.

Human protein reference database as a discovery resource for proteomics

A human in vitro model system for investigating genome-wide host responses to SARS coronavirus infection

High-throughput mapping of a dynamic signaling network in mammalian cells

NFAT proteins: key regulators of T-cell development and function

The BioGRID Interaction Database: 2008 update

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

Genome-wide analysis of protein-protein interactions and involvement of viral proteins in SARS-CoV replication

Genomic characterization of severe acute respiratory syndrome-related coronavirus in European bats and classification of coronaviruses based on partial RNA-dependent RNA polymerase gene sequences

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10

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Christian Drosten

Rolf Hilgenfeld

Stefan Pöhlmann

Susanne Pfefferle

Marcel Alexander Müller

Friedemann Weber

Caroline C Friedel

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2011-10-27T00:00:00Z

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51760931

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22046132

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severe acute respiratory syndrome-related coronavirus

severe acute respiratory syndrome coronavirus

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