Synthetic zinc finger proteins: the advent of targeted gene regulation and genome modification technologies. - Test2 - elhamkhani - TriplyDB

Synthetic zinc finger proteins: the advent of targeted gene regulation and genome modification technologies.

Synthetic zinc finger proteins: the advent of targeted gene regulation and genome modification technologies.

http://www.wikidata.org/entity/Q34070213

about

Genome-editing Technologies for Gene and Cell Therapy Enabling functional genomics with genome engineering Epigenetic Editing: On the Verge of Reprogramming Gene Expression at Will PatternQuery: web application for fast detection of biomacromolecular structural patterns in the entire Protein Data Bank.Engineering synthetic TALE and CRISPR/Cas9 transcription factors for regulating gene expression Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector.Correction of dystrophin expression in cells from Duchenne muscular dystrophy patients through genomic excision of exon 51 by zinc finger nucleases.Improved cell-penetrating zinc-finger nuclease proteins for precision genome engineering Direct protein delivery to mammalian cells using cell-permeable Cys2-His2 zinc-finger domains.Modulation of Estrogen Response Element-Driven Gene Expressions and Cellular Proliferation with Polar Directions by Designer Transcription Regulators Enhanced MyoD-induced transdifferentiation to a myogenic lineage by fusion to a potent transactivation domain Redesigning Recombinase Specificity for Safe Harbor Sites in the Human Genome Modular Synthetic Inverters from Zinc Finger Proteins and Small RNAs.Reactivation of Latent HIV-1 Expression by Engineered TALE Transcription Factors.TALEored Epigenetics: A DNA-Binding Scaffold for Programmable Epigenome Editing and Analysis.Targeted genome regulation via synthetic programmable transcriptional regulators.CRISPR-mediated Activation of Latent HIV-1 Expression Conservative site-specific and single-copy transgenesis in human LINE-1 elements.Artificial zinc finger DNA binding domains: versatile tools for genome engineering and modulation of gene expression.Design, Assembly, and Characterization of TALE-Based Transcriptional Activators and Repressors Editing the epigenome: technologies for programmable transcription and epigenetic modulation.Genomic targeting of epigenetic probes using a chemically tailored Cas9 system.The Development of TALE Nucleases for Biotechnology.Gene therapies that restore dystrophin expression for the treatment of Duchenne muscular dystrophy.Efficient delivery of nuclease proteins for genome editing in human stem cells and primary cells.Integrating gene synthesis and microfluidic protein analysis for rapid protein engineering.Engineering and Application of Zinc Finger Proteins and TALEs for Biomedical Research.Creating class I MHC-null pigs using guide RNA and the Cas9 endonuclease.Genome engineering: a new approach to gene therapy for neuromuscular disorders.A designed DNA binding motif that recognizes extended sites and spans two adjacent major grooves Engineered Zinc Finger DNA-Binding Domains: Synthesis, Assessment of DNA-Binding Affinity, and Direct Protein Delivery to Mammalian Cells.Genome Engineering for Personalized Arthritis Therapeutics.Heterogeneous-Backbone Foldamer Mimics of Zinc Finger Tertiary Structure.The conserved basic residues and the charged amino acid residues at the α-helix of the zinc finger motif regulate the nuclear transport activity of triple C2H2 zinc finger proteins.Utrophin up-regulation by artificial transcription factors induces muscle rescue and impacts the neuromuscular junction in mdx mice.Harnessing natural DNA modifying activities for editing of the genome and epigenome.Epigenetic editing: How cutting-edge targeted epigenetic modification might provide novel avenues for autoimmune disease therapy.DNA-binding miniproteins based on zinc fingers. Assessment of the interaction using nanopores.

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P2860

Synthetic zinc finger proteins: the advent of targeted gene regulation and genome modification technologies.

http://www.wikidata.org/entity/Q34070213

description

2014 nî lūn-bûn

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2014 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2014 թվականի մայիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Synthetic zinc finger proteins ...... ome modification technologies.

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Synthetic zinc finger proteins ...... ome modification technologies.

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Synthetic zinc finger proteins ...... ome modification technologies.

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Synthetic zinc finger proteins ...... ome modification technologies.

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Synthetic zinc finger proteins ...... ome modification technologies.

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Synthetic zinc finger proteins ...... ome modification technologies.

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Synthetic zinc finger proteins ...... ome modification technologies.

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Synthetic zinc finger proteins ...... ome modification technologies.

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Synthetic zinc finger proteins ...... ome modification technologies.

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Accounts of Chemical Research

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Synthetic zinc finger proteins ...... ome modification technologies.

@en

P2093

Carlos F Barbas

http://www.w3.org/2001/XMLSchema#string

Charles A Gersbach

http://www.w3.org/2001/XMLSchema#string

Thomas Gaj

http://www.w3.org/2001/XMLSchema#string

P2860

Assembly of combinatorial antibody libraries on phage surfaces: the gene III site

Building zinc fingers by selection: toward a therapeutic application

RNA-guided human genome engineering via Cas9

Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription

Multiplex genome engineering using CRISPR/Cas systems

Toward controlling gene expression at will: specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks

A rapid, generally applicable method to engineer zinc fingers illustrated by targeting the HIV-1 promoter

Positive and negative regulation of endogenous genes by designed transcription factors

Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification

Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly

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2309-2318

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scholarly article

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10.1021/AR500039W

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8

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47

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2014-05-30T00:00:00Z

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262786587

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24877793

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4139171

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