Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia - Test2 - elhamkhani - TriplyDB

Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia

Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia

http://www.wikidata.org/entity/Q34075585

about

Elevated O-GlcNAc-dependent signaling through inducible mOGT expression selectively triggers apoptosis Hexosamines, insulin resistance, and the complications of diabetes: current status.Caenorhabditis elegans ortholog of a diabetes susceptibility locus: oga-1 (O-GlcNAcase) knockout impacts O-GlcNAc cycling, metabolism, and dauer Insulin receptor signaling in normal and insulin-resistant states Functional O-GlcNAc modifications: implications in molecular regulation and pathophysiology O-GlcNAcylation and Metabolic Reprograming in Cancer Elevation of Global O-GlcNAc Levels in 3T3-L1 Adipocytes by Selective Inhibition of O-GlcNAcase Does Not Induce Insulin Resistance GlcNAcstatins are nanomolar inhibitors of human O -GlcNAcase inducing cellular hyper- O -GlcNAcylation Substrate and product analogues as human O-GlcNAc transferase inhibitors Inhibition of a bacterial O-GlcNAcase homologue by lactone and lactam derivatives: structural, kinetic and thermodynamic analyses Inhibition of O-GlcNAcase Using a Potent and Cell-Permeable Inhibitor Does Not Induce Insulin Resistance in 3T3-L1 Adipocytes Gaining insight into the inhibition of glycoside hydrolase family 20 exo-β-N-acetylhexosaminidases using a structural approach The hexosamine signaling pathway: deciphering the "O-GlcNAc code"A PGC-1alpha-O-GlcNAc transferase complex regulates FoxO transcription factor activity in response to glucose.O-GlcNAc regulates FoxO activation in response to glucose.O-GlcNAc cycling mutants modulate proteotoxicity in Caenorhabditis elegans models of human neurodegenerative diseases.O-GlcNAc modifications regulate cell survival and epiboly during zebrafish development.The hexosamine signaling pathway: O-GlcNAc cycling in feast or famine The essential role of YAP O-GlcNAcylation in high-glucose-stimulated liver tumorigenesis Quantitative secretome and glycome of primary human adipocytes during insulin resistance.Dynamic O-GlcNAc cycling at promoters of Caenorhabditis elegans genes regulating longevity, stress, and immunity.A Caenorhabditis elegans model of insulin resistance: altered macronutrient storage and dauer formation in an OGT-1 knockout.Increased expression of beta-N-acetylglucosaminidase in erythrocytes from individuals with pre-diabetes and diabetes.O-GlcNAc signaling in the cardiovascular system.O-GlcNAc signaling: a metabolic link between diabetes and cancer?Blocking O-linked GlcNAc cycling in Drosophila insulin-producing cells perturbs glucose-insulin homeostasis.OGA inhibition by GlcNAc-selenazoline Versatile O-GlcNAc transferase assay for high-throughput identification of enzyme variants, substrates, and inhibitors.Hepatic FoxO1 integrates glucose utilization and lipid synthesis through regulation of Chrebp O-glycosylation.O-GlcNAcylation: a novel post-translational mechanism to alter vascular cellular signaling in health and disease: focus on hypertension.Increased hexosamine pathway flux and high fat feeding are not additive in inducing insulin resistance: evidence for a shared pathway Disruption of O-GlcNAc Cycling in C. elegans Perturbs Nucleotide Sugar Pools and Complex Glycans.O-GlcNAcylation: a novel pathway contributing to the effects of endothelin in the vasculature.O-GlcNAc and the epigenetic regulation of gene expression.Multiple tissue-specific roles for the O-GlcNAc post-translational modification in the induction of and complications arising from type II diabetes.Global O-GlcNAc Levels Modulate Transcription of the Adipocyte Secretome during Chronic Insulin Resistance.O-linked-N-acetylglucosamine cycling and insulin signaling are required for the glucose stress response in Caenorhabditis elegans Identification of O-GlcNAc modification targets in mouse retinal pericytes: implication of p53 in pathogenesis of diabetic retinopathy.O-GlcNAc turns twenty: functional implications for post-translational modification of nuclear and cytosolic proteins with a sugar.Conditional knock-out reveals a requirement for O-linked N-Acetylglucosaminase (O-GlcNAcase) in metabolic homeostasis

P2860

Q24299073-8ED8802A-6365-472F-BED0-86456408FB13 Q24538581-A88AF5E6-CF70-4E52-9C85-7442DF7BB910 Q24670972-A7CAABDA-4FD2-4B59-B5F3-C23C57312364 Q26823171-71127EE9-729D-4C58-A6E0-19E27A762854 Q27009399-40FF6E80-5A16-474D-94FE-261F7FAE3B5E Q27027028-BA0DBCF5-A026-4146-BE68-78A68EAF1EA0 Q27652457-8449028E-491C-44DC-AA8B-0C3483AC99BE Q27654050-F02C73E6-EDAF-48EF-A187-A36D3C8F62AF Q27663568-B784D2C5-F161-4324-B6D4-74630689592B Q27663888-A026BBBA-C2F7-4AE5-BD06-F63861A437A7 Q27664569-58CC0C80-1FF1-4F96-ACCE-F25F4E00E489 Q27677503-4214D6D8-47DB-4D53-B01B-205DAD8A5EC8 Q28284365-FC993938-D71D-483D-A34A-2587B0F2B2CC Q30437005-2F1040C0-3684-435E-A645-04149105FFFB Q30439420-D8FD78A8-07A3-4C2B-9874-AA4D9CE4CD32 Q30528027-29F5C77B-B2D8-4226-BC8D-9BD86262C369 Q33433251-1FF8589B-8616-4302-B45F-E84A6BAFB16E Q33625053-59ED0C1A-F322-437A-9095-D49F24ACDBAC Q33654365-54E981C4-41ED-4B5A-A07E-C9C7DC868300 Q33749585-DE8D2477-393F-4306-94C1-3DCB5F2D61E2 Q33842100-8BB05B56-1194-4CEC-A03B-2C1938AC75CF Q33913856-716A3A00-6866-4E28-A90C-994500D2C960 Q33930349-91068AEB-B210-4D99-A949-D2E053FA9E4B Q34056858-8C21CE3F-63E0-43E7-8F7D-D7FE5CC776ED Q34172895-78135297-C0D1-45F7-A82C-A0D0077540DF Q34352417-249CF029-CCFE-4766-BBCB-EE6C3511B44C Q34411395-7A214D6B-71C8-43A6-BA7E-A199C02686CC Q34434068-425706DC-E0DF-418F-9D02-40C80C43D7FF Q34442922-2F3C30F5-D5EB-4A09-B727-55E4EBB33C22 Q34498193-788C6923-B0C7-477D-94DF-8A1D50F6EA2E Q34538415-EAB28F79-D3C7-4BDB-8D5F-1E6C84DCDBAC Q34562985-666E6FBA-0C56-4E01-A936-0D235647DB87 Q34598611-992152BF-847A-4920-962F-D8AA4707ED41 Q34683048-35B6631E-71E6-48B2-AADB-B66545B23D18 Q34683091-C426CCC3-D0D3-433F-AE84-4188B7E0FE27 Q34999404-1B8F7863-EAF4-47D7-AFAE-B4AB70BC3B77 Q35065486-26419454-278B-4AC2-A6E3-99D0ECC53D61 Q35161621-CCDA1EC1-4AD6-4257-8F79-2CEF7AD51D5C Q35163991-42C4037C-C90D-4F41-AA2D-D2668290AF03 Q35172669-7DF40B8F-6CA4-4F90-A65A-9B7418D9C42D

P2860

Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia

http://www.wikidata.org/entity/Q34075585

description

2002 nî lūn-bûn

@nan

2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2002年の論文

@ja

2002年論文

@yue

2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

@wuu

name

Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia

@ast

Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia

@en

Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia

@nl

type

label

Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia

@ast

Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia

@en

Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia

@nl

prefLabel

Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia

@ast

Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia

@en

Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia

@nl

P1433

Q34075585-8D9FF6C8-2F64-4919-9019-4921107C590B

P1476

Q34075585-16C96BE9-FA9B-4A90-BC9D-2D10210A00A4

P2093

Q34075585-27F520B0-5525-4FFD-A084-BD22E1C5276E

Q34075585-3A4784A3-CB8A-4A7A-9A1D-022E93DDA316

Q34075585-3E03D6EA-A69B-4A47-8C5C-E40CB54F9DF2

Q34075585-573BAE91-AE94-4DC3-A572-0064437E01AA

Q34075585-66A6F0E8-4165-4F31-99D9-C97D2AD7495C

Q34075585-DF7346B2-53B0-4B4B-B58D-C89BF052EE01

P2860

Q34075585-0AC882B3-234D-42A8-BA05-42088CC3716C

Q34075585-0DA5E8B5-7C57-4FEC-A6DF-26C62D9B9F32

Q34075585-0F5A7300-C8C3-40C0-9187-FCB81EFDC2D4

Q34075585-11A0C18D-A591-42BF-918A-E3B5E2FE8F3A

Q34075585-22F2D92E-3EDA-47A9-A88A-33D4676294D6

Q34075585-24124718-492D-4C84-85F1-EBCD4484B46F

Q34075585-2582CCDD-5EF4-4F95-BC56-92398F3B7838

Q34075585-2B680DFE-A846-4E52-8750-9377FDC65C5D

Q34075585-2C3BFFE6-6AEE-4C86-98F5-E37445486477

Q34075585-34975F93-8360-457C-9361-C404B343B5DC

P304

Q34075585-201979EE-6F5C-484A-9521-E3865A9364E9

P31

Q34075585-F5A8CF7D-5FF8-4717-8290-22499B058FFF

P356

Q34075585-AB337E4B-5C0C-42C3-802E-650645BC6686

P407

Q34075585-28D42BF9-F530-4AA3-85FB-106C74934E44

P433

Q34075585-E2B16F24-C132-49F3-9CAE-AB61DF46A572

P478

Q34075585-DA29110C-C395-4F5D-BFFE-387C173FBA01

P50

Q34075585-7A26ED63-9AFD-4A55-B340-55271F6F4A3C

P577

Q34075585-43490E03-7E01-467E-9920-036974C0BAA6

P5875

Q34075585-C539322D-7275-4086-8031-7CB874310A35

P698

Q34075585-33954AF3-0D41-41C1-A19A-EE22719EBEF9

P921

Q34075585-6E21BADE-14DC-47CD-A9AB-C2F6570D4D75

P932

Q34075585-059534A6-52EF-4140-9B05-800D4A8CF4B0

P356

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia

@en

P2093

Dona C Love

http://www.w3.org/2001/XMLSchema#string

Glendon J Parker

http://www.w3.org/2001/XMLSchema#string

John A Hanover

http://www.w3.org/2001/XMLSchema#string

Mark Hazel

http://www.w3.org/2001/XMLSchema#string

Robert C Cooksey

http://www.w3.org/2001/XMLSchema#string

William A Lubas

http://www.w3.org/2001/XMLSchema#string

P2860

Dynamic O-glycosylation of nuclear and cytosolic proteins: cloning and characterization of a neutral, cytosolic beta-N-acetylglucosaminidase from human brain

O-glycosylation of eukaryotic transcription factors: implications for mechanisms of transcriptional regulation

Dynamic glycosylation of nuclear and cytosolic proteins. Cloning and characterization of a unique O-GlcNAc transferase with multiple tetratricopeptide repeats

O-Linked GlcNAc transferase is a conserved nucleocytoplasmic protein containing tetratricopeptide repeats

O-linkage of N-acetylglucosamine to Sp1 activation domain inhibits its transcriptional capability

Obesity and insulin resistance

Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation

The O-GlcNAc transferase gene resides on the X chromosome and is essential for embryonic stem cell viability and mouse ontogeny

Functional expression of O-linked GlcNAc transferase. Domain structure and substrate specificity

Human GLUT4/muscle-fat glucose-transporter gene. Characterization and genetic variation

P304

10695-10699

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.152346899

http://www.w3.org/2001/XMLSchema#string

P407

P433

16

http://www.w3.org/2001/XMLSchema#string

P478

99

http://www.w3.org/2001/XMLSchema#string

P50

P577

2002-07-22T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

11246022

http://www.w3.org/2001/XMLSchema#string

P698

12136128

http://www.w3.org/2001/XMLSchema#string

P921

P932

125016

http://www.w3.org/2001/XMLSchema#string