An alphavirus vector overcomes the presence of neutralizing antibodies and elevated numbers of Tregs to induce immune responses in humans with advanced cancer
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Alphavirus-based vaccinesNovel recombinant alphaviral and adenoviral vectors for cancer immunotherapyReplicon RNA Viral Vectors as VaccinesViral vector-based influenza vaccines.High efficiency of alphaviral gene transfer in combination with 5-fluorouracil in a mouse mammary tumor model.Improved cytotoxic T-lymphocyte immune responses to a tumor antigen by vaccines co-expressing the SLAM-associated adaptor EAT-2.Virus-vectored influenza virus vaccines.Strengthened tumor antigen immune recognition by inclusion of a recombinant Eimeria antigen in therapeutic cancer vaccination.Viral vector-based therapeutic cancer vaccinesCombination of alphavirus replicon particle-based vaccination with immunomodulatory antibodies: therapeutic activity in the B16 melanoma mouse model and immune correlates.Neoadjuvant administration of Semliki Forest virus expressing interleukin-12 combined with attenuated Salmonella eradicates breast cancer metastasis and achieves long-term survival in immunocompetent mice.Lack of interference with immunogenicity of a chimeric alphavirus replicon particle-based influenza vaccine by preexisting antivector immunityPhase I safety and immunogenicity evaluations of an alphavirus replicon HIV-1 subtype C gag vaccine in healthy HIV-1-uninfected adults.Novel adenoviral vector induces T-cell responses despite anti-adenoviral neutralizing antibodies in colorectal cancer patientsPolyclonal immune responses to antigens associated with cancer signaling pathways and new strategies to enhance cancer vaccinesCo-delivery of antigen and IL-12 by Venezuelan equine encephalitis virus replicon particles enhances antigen-specific immune responses and antitumor effects.Targeting Carcinoembryonic Antigen with DNA Vaccination: On-Target Adverse Events Link with Immunologic and Clinical Outcomes.Potential targets for pancreatic cancer immunotherapeutics.Genetic cancer vaccines: current status and perspectives.Cancer vaccines targeting carcinoembryonic antigen: state-of-the-art and future promise.A development that may evolve into a revolution in medicine: mRNA as the basis for novel, nucleotide-based vaccines and drugsRNA-based drugs and vaccines.Self-replicating alphavirus RNA vaccines.Designing effective vaccines for colorectal cancer.RNA-based viral vectors.Alphavirus-based vaccines in melanoma: rationale and potential improvements in immunotherapeutic combinations.Anti-tumor effect of the alphavirus-based virus-like particle vector expressing prostate-specific antigen in a HLA-DR transgenic mouse model of prostate cancer.Viral and Synthetic RNA Vector Technologies and Applications.Oncolytic Alphaviruses in Cancer Immunotherapy.Semliki Forest virus biodistribution in tumor-free and 4T1 mammary tumor-bearing mice: a comparison of transgene delivery by recombinant virus particles and naked RNA replicon.Bridging infectious disease vaccines with cancer immunotherapy: a role for targeted RNA based immunotherapeutics.Preliminary Evaluation of a Bunyavirus Vector for Cancer Immunotherapy.Trial Watch: DNA vaccines for cancer therapy.Alphavirus-Based Vaccines.Semliki Forest VirusExpression SystemThe Journey of Virus Engineered Dendritic Cells From Bench to Bedside: A Bumpy Road
P2860
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P2860
An alphavirus vector overcomes the presence of neutralizing antibodies and elevated numbers of Tregs to induce immune responses in humans with advanced cancer
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
An alphavirus vector overcomes ...... in humans with advanced cancer
@ast
An alphavirus vector overcomes ...... in humans with advanced cancer
@en
An alphavirus vector overcomes ...... in humans with advanced cancer
@nl
type
label
An alphavirus vector overcomes ...... in humans with advanced cancer
@ast
An alphavirus vector overcomes ...... in humans with advanced cancer
@en
An alphavirus vector overcomes ...... in humans with advanced cancer
@nl
prefLabel
An alphavirus vector overcomes ...... in humans with advanced cancer
@ast
An alphavirus vector overcomes ...... in humans with advanced cancer
@en
An alphavirus vector overcomes ...... in humans with advanced cancer
@nl
P2093
P2860
P356
P1476
An alphavirus vector overcomes ...... in humans with advanced cancer
@en
P2093
Amy C Hobeika
Bolyn Hubby
Bruce K Burnett
Donna Niedzwiecki
Gayathri R Devi
H Kim Lyerly
Jonathan Smith
Michael A Morse
Peter Berglund
Sarah Negri
P2860
P304
P356
10.1172/JCI42672
P407
P577
2010-08-02T00:00:00Z