Recent advances in developing small molecules targeting RNA.
about
Recognition of RNA duplexes by chemically modified triplex-forming oligonucleotidesSmall molecules targeting viral RNAStructure based approaches for targeting non-coding RNAs with small moleculesSmall molecule chemical probes of microRNA functionA Disconnect between High-Affinity Binding and Efficient Regulation by Antifolates and Purines in the Tetrahydrofolate RiboswitchSelective small-molecule inhibition of an RNA structural elementHigh-affinity recognition of HIV-1 frameshift-stimulating RNA alters frameshifting in vitro and interferes with HIV-1 infectivityDesign of a bioactive small molecule that targets r(AUUCU) repeats in spinocerebellar ataxia 10Inhibition of Non-ATG Translational Events in Cells via Covalent Small Molecules Targeting RNAApproaches to Validate and Manipulate RNA Targets with Small Molecules in CellsCharacterization and in vitro activity of a branched peptide boronic acid that interacts with HIV-1 RRE RNAStructure of the myotonic dystrophy type 2 RNA and designed small molecules that reduce toxicity.Ametantrone-based compounds as potential regulators of Tau pre-mRNA alternative splicing.Methods to enable the design of bioactive small molecules targeting RNA.Two-dimensional combinatorial screening enables the bottom-up design of a microRNA-10b inhibitorSelective inhibitors of trypanosomal uridylyl transferase RET1 establish druggability of RNA post-transcriptional modifications.Template-directed synthesis of a small molecule-antisense conjugate targeting an mRNA structure.Picazoplatin, an azide-containing platinum(II) derivative for target analysis by click chemistry.Hepatitis C virus translation inhibitors targeting the internal ribosomal entry site.Selectively guanidinylated aminoglycosides as antibiotics.Identifying the preferred RNA motifs and chemotypes that interact by probing millions of combinations.Identification of biologically active, HIV TAR RNA-binding small molecules using small molecule microarrays.Efficient in silico exploration of RNA interhelical conformations using Euler angles and WExploreDefining RNA motif-aminoglycoside interactions via two-dimensional combinatorial screening and structure-activity relationships through sequencing.Targeting the r(CGG) repeats that cause FXTAS with modularly assembled small molecules and oligonucleotidesTargeting folded RNA: a branched peptide boronic acid that binds to a large surface area of HIV-1 RRE RNAFeatures of modularly assembled compounds that impart bioactivity against an RNA target.Aberrant RNA homeostasis in amyotrophic lateral sclerosis: potential for new therapeutic targets?Sequence-based design of bioactive small molecules that target precursor microRNAs.Recent discoveries and applications involving small-molecule microarraysBottom-up design of small molecules that stimulate exon 10 skipping in mutant MAPT pre-mRNAProbing RNA-protein networks: biochemistry meets genomicsHIV-1 drug discovery: targeting folded RNA structures with branched peptides.mRNA regulation: A patch for a splice.RNA Structures as Mediators of Neurological Diseases and as Drug Targets.Analysis of secondary structural elements in human microRNA hairpin precursors.A highly conserved G-rich consensus sequence in hepatitis C virus core gene represents a new anti-hepatitis C target.Small-molecule approaches toward the targeting of oncogenic miRNAs: roadmap for the discovery of RNA modulators.Design, Synthesis and Structure-Activity Relationship Optimization of Lycorine Derivatives for HCV Inhibition.Development of Small Molecules with a Noncanonical Binding Mode to HIV-1 Trans Activation Response (TAR) RNA.
P2860
Q24599584-FF796F8F-1F4D-4911-B825-E84B916E4D7FQ26745817-4CDD3550-DD95-4599-9288-2EA117484EADQ26858823-5F86BD39-7843-4D25-BDB2-B3F1D2FD0F39Q27025357-F47C2CE0-0D2F-493A-A21C-4EB4B5E75510Q27681170-66F682C5-410D-49F2-A060-DFA30B4B6792Q27702218-4E635396-9DC9-49E4-A311-041A283436F7Q28305122-A2E29077-CF32-4BCE-B324-D6D0DBDD11FAQ28828843-065522B8-F180-45B9-816E-4A734FF8D266Q28833596-966AF9E3-42B3-4C53-B705-0CEE318D431EQ28833658-485DE297-3CBF-4AD2-BBEC-5385061E857BQ30276963-1E0BC58C-76F2-49FE-973D-FACCA95320D1Q30573524-670C6850-ACED-485C-A84E-DBF17949AD6DQ30867681-CC7335CB-DC4D-4EC2-B278-3B69BBC4EBB7Q33609375-3365C7CF-8309-41BF-AADD-CE276662404CQ33692781-8C3816BF-6A07-4CC3-A9B2-A3374635F77EQ33739738-D15F415F-A31E-4ED8-B7F7-BCBDEC2B6E5DQ33835923-5A94F5F4-A991-4E12-891D-E24C16FC55A0Q34033965-B43D2024-B7DE-4A22-A26F-2E242958CDCBQ34038589-80645109-7271-451A-9356-F1DE12639850Q34283886-E3E6DB0A-A910-489B-AF6A-05B1AEFF9CDDQ34437297-99C03949-2B51-4C65-9739-4610AAB182B8Q34489904-8526739E-FA9F-46C9-99EC-CAA1A5720671Q34510011-AB53FE3C-603F-4FED-92E9-ABA3471A3CDCQ34747084-7C1E1C8D-8B36-4A54-8400-C980BE03952FQ34879217-590C2F8F-D2FC-453B-BBCF-C0CC749A2FC2Q34909697-E2B88DEF-5DA5-455A-A4B6-6F99AD5A1F1FQ34986416-4E18C8C0-9DED-4D79-A6CD-5E00EE5A6D2CQ35019375-D42201FC-886A-4791-BC50-76A581CD9358Q35089454-B26FC0A1-523F-4781-B046-561DFDEB5BE3Q35096100-FEF7A1AC-9EFE-4195-B1FC-A83EA4EFD80AQ35101063-9AE00838-C000-4E6C-9723-01A0818F5019Q35122339-E632BA01-48A3-420C-83B5-B372E6560B83Q35626292-F7298E0F-D354-444E-BF62-13E2AC35B6F4Q35665738-B02404DF-56EC-4436-9EE5-04E733D6EC80Q35868044-F4A49610-130F-4270-BAB5-077CB1CF224EQ35940120-BF9F14E5-1855-424C-8F21-F80A844A4920Q35981554-FA904E1B-F068-481A-BA05-1C8ADA10D4A3Q36009522-12E13516-B844-4884-B3CE-0A2D0F53DC6CQ36128724-1A241E3B-4715-4466-826D-65B1F42B6542Q36230686-B318D192-2BCD-4600-A382-B2AD1F8762B7
P2860
Recent advances in developing small molecules targeting RNA.
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Recent advances in developing small molecules targeting RNA.
@ast
Recent advances in developing small molecules targeting RNA.
@en
Recent advances in developing small molecules targeting RNA.
@nl
type
label
Recent advances in developing small molecules targeting RNA.
@ast
Recent advances in developing small molecules targeting RNA.
@en
Recent advances in developing small molecules targeting RNA.
@nl
prefLabel
Recent advances in developing small molecules targeting RNA.
@ast
Recent advances in developing small molecules targeting RNA.
@en
Recent advances in developing small molecules targeting RNA.
@nl
P356
P1433
P1476
Recent advances in developing small molecules targeting RNA.
@en
P2093
Lirui Guan
Matthew D Disney
P356
10.1021/CB200447R
P577
2012-01-12T00:00:00Z