Network models for molecular kinetics and their initial applications to human health
about
Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15Taming the complexity of protein foldingExploiting a natural conformational switch to engineer an interleukin-2 'superkine'Quantitative comparison of alternative methods for coarse-graining biological networksMarkov State Models of gene regulatory networksA chemical group graph representation for efficient high-throughput analysis of atomistic protein simulations.Extensive conformational heterogeneity within protein cores.Equilibrium fluctuations of a single folded protein reveal a multitude of potential cryptic allosteric sites.The protein folding network indicates that the ultrafast folding mutant of villin headpiece subdomain has a deeper folding funnelMechanism of action of thalassospiramides, a new class of calpain inhibitorsDiscovery of multiple hidden allosteric sites by combining Markov state models and experimentsSimbios: an NIH national center for physics-based simulation of biological structures.Improved coarse-graining of Markov state models via explicit consideration of statistical uncertainty.Modelling proteins' hidden conformations to predict antibiotic resistance.Atomistic folding simulations of the five-helix bundle protein λ(6−85).Building a kinetic Monte Carlo model with a chosen accuracy.Cluster analysis of accelerated molecular dynamics simulations: A case study of the decahedron to icosahedron transition in Pt nanoparticles.The folding mechanism and key metastable state identification of the PrP127-147 monomer studied by molecular dynamics simulations and Markov state model analysis.
P2860
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P2860
Network models for molecular kinetics and their initial applications to human health
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Network models for molecular kinetics and their initial applications to human health
@ast
Network models for molecular kinetics and their initial applications to human health
@en
Network models for molecular kinetics and their initial applications to human health
@nl
type
label
Network models for molecular kinetics and their initial applications to human health
@ast
Network models for molecular kinetics and their initial applications to human health
@en
Network models for molecular kinetics and their initial applications to human health
@nl
prefLabel
Network models for molecular kinetics and their initial applications to human health
@ast
Network models for molecular kinetics and their initial applications to human health
@en
Network models for molecular kinetics and their initial applications to human health
@nl
P2860
P356
P1433
P1476
Network models for molecular kinetics and their initial applications to human health
@en
P2093
Gregory R Bowman
Vijay S Pande
P2860
P2888
P304
P356
10.1038/CR.2010.57
P50
P577
2010-04-27T00:00:00Z
P5875
P6179
1033643205