PU.1 inhibits the erythroid program by binding to GATA-1 on DNA and creating a repressive chromatin structure.
about
IL-32θ negatively regulates IL-1β production through its interaction with PKCδ and the inhibition of PU.1 phosphorylationSystematic RNAi studies on the role of Sp/KLF factors in globin gene expression and erythroid differentiationSimilarities between the Epstein-Barr Virus (EBV) Nuclear Protein EBNA1 and the Pioneer Transcription Factor FoxA: Is EBNA1 a "Bookmarking" Oncoprotein that Alters the Host Cell Epigenotype?A general model for binary cell fate decision gene circuits with degeneracy: indeterminacy and switch behavior in the absence of cooperativityCell autonomous roles for AP-2alpha in lens vesicle separation and maintenance of the lens epithelial cell phenotypeRegulation of alphaA-crystallin via Pax6, c-Maf, CREB and a broad domain of lens-specific chromatinGaucher disease: transcriptome analyses using microarray or mRNA sequencing in a Gba1 mutant mouse model treated with velaglucerase alfa or imigluceraseLeukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiationHistiocytic sarcoma as a secondary malignancy: pathobiology, diagnosis, and treatment.Identification of pax6-dependent gene regulatory networks in the mouse lens.Computational modeling of the hematopoietic erythroid-myeloid switch reveals insights into cooperativity, priming, and irreversibilityPU.1 directly regulates cdk6 gene expression, linking the cell proliferation and differentiation programs in erythroid cellsPro-inflammatory cytokine-mediated anemia: regarding molecular mechanisms of erythropoiesis.From hematopoietic progenitors to B cells: mechanisms of lineage restriction and commitmentA large gene network in immature erythroid cells is controlled by the myeloid and B cell transcriptional regulator PU.1.Multiple ETS family proteins regulate PF4 gene expression by binding to the same ETS binding site.Extensive remodeling of DC function by rapid maturation-induced transcriptional silencing.Epigenetic silencing of Bim transcription by Spi-1/PU.1 promotes apoptosis resistance in leukaemiaGATA-1 directly regulates p21 gene expression during erythroid differentiationTranscriptional control of erythropoiesis: emerging mechanisms and principles.Role of helix-loop-helix proteins during differentiation of erythroid cells.Reprogramming leukemia cells to terminal differentiation and growth arrest by RNA interference of PU.1.Regulation of early T-lineage gene expression and developmental progression by the progenitor cell transcription factor PU.1.Distinctive signatures of histone methylation in transcribed coding and noncoding human beta-globin sequencesLoss of IKKβ but Not NF-κB p65 Skews Differentiation towards Myeloid over Erythroid Commitment and Increases Myeloid Progenitor Self-Renewal and Functional Long-Term Hematopoietic Stem Cells.A core erythroid transcriptional network is repressed by a master regulator of myelo-lymphoid differentiation.Distinct embryonic expression and localization of CBP and p300 histone acetyltransferases at the mouse alphaA-crystallin locus in lens.Mechanisms of eosinophilia in the pathogenesis of hypereosinophilic disordersGcn5 is required for PU.1-dependent IL-9 induction in Th9 cells.Transcription factor-mediated epigenetic reprogramming.Spi-1/PU.1 activates transcription through clustered DNA occupancy in erythroleukemiaH1 linker histone promotes epigenetic silencing by regulating both DNA methylation and histone H3 methylation.High resolution methylome analysis reveals widespread functional hypomethylation during adult human erythropoiesis.Chromatin structure regulation in transforming growth factor-beta-directed epithelial-mesenchymal transition.Epigenetic regulation of normal and malignant hematopoiesis.Understanding transcriptional regulatory networks using computational models.Spi-1 and Fli-1 directly activate common target genes involved in ribosome biogenesis in Friend erythroleukemic cells.Epigenetic gene regulation in stem cells and correlation to cancerEpigenetics of beta-globin gene regulationGraded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fate.
P2860
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P2860
PU.1 inhibits the erythroid program by binding to GATA-1 on DNA and creating a repressive chromatin structure.
description
2005 nî lūn-bûn
@nan
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
PU.1 inhibits the erythroid pr ...... epressive chromatin structure.
@ast
PU.1 inhibits the erythroid pr ...... epressive chromatin structure.
@en
PU.1 inhibits the erythroid pr ...... epressive chromatin structure.
@nl
type
label
PU.1 inhibits the erythroid pr ...... epressive chromatin structure.
@ast
PU.1 inhibits the erythroid pr ...... epressive chromatin structure.
@en
PU.1 inhibits the erythroid pr ...... epressive chromatin structure.
@nl
prefLabel
PU.1 inhibits the erythroid pr ...... epressive chromatin structure.
@ast
PU.1 inhibits the erythroid pr ...... epressive chromatin structure.
@en
PU.1 inhibits the erythroid pr ...... epressive chromatin structure.
@nl
P2093
P2860
P356
P1433
P1476
PU.1 inhibits the erythroid pr ...... epressive chromatin structure.
@en
P2093
Arthur I Skoultchi
Derek F Amanatullah
Michael Papetti
Tomas Stopka
P2860
P304
P356
10.1038/SJ.EMBOJ.7600834
P407
P577
2005-10-13T00:00:00Z