Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors.
about
A domain-oriented approach to the reduction of combinatorial complexity in signal transduction networksA quantitative protein interaction network for the ErbB receptors using protein microarraysEngineered epidermal growth factor mutants with faster binding on-rates correlate with enhanced receptor activationComputational modelling of the receptor-tyrosine-kinase-activated MAPK pathwayMechanism of the spatio-temporal regulation of Ras and Rap1.Uncovering quantitative protein interaction networks for mouse PDZ domains using protein microarraysAn ultrasensitive sorting mechanism for EGF receptor endocytosisA comprehensive pathway map of epidermal growth factor receptor signalingAsynchronous adaptive time step in quantitative cellular automata modelingUltrasensitization: switch-like regulation of cellular signaling by transcriptional inductionIterative approach to model identification of biological networksNormal morphogenesis of epithelial tissues and progression of epithelial tumors.Tumor cell migration in complex microenvironmentsNovel Reporter for Faithful Monitoring of ERK2 Dynamics in Living Cells and Model Organisms.A Neutrophil Phenotype Model for Extracorporeal Treatment of SepsisSystems biology approaches for advancing the discovery of effective drug combinationsTime-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modulesNetwork Inference and Biological DynamicsStimulus design for model selection and validation in cell signalingAssociation rate constants of ras-effector interactions are evolutionarily conservedSimulating EGFR-ERK signaling control by scaffold proteins KSR and MP1 reveals differential ligand-sensitivity co-regulated by Cbl-CIN85 and endophilinComputational modeling and analysis of insulin induced eukaryotic translation initiationModeling of tumor progression in NSCLC and intrinsic resistance to TKI in loss of PTEN expressionA comprehensive, multi-scale dynamical model of ErbB receptor signal transduction in human mammary epithelial cellsIntegrative modelling of the influence of MAPK network on cancer cell fate decisionParameter trajectory analysis to identify treatment effects of pharmacological interventionsPerturbation biology: inferring signaling networks in cellular systemsQuantitative characterization of cellular membrane-receptor heterogeneity through statistical and computational modelingAccelerated Sensitivity Analysis in High-Dimensional Stochastic Reaction NetworksNetwork reconstruction based on proteomic data and prior knowledge of protein connectivity using graph theoryEnzyme Sequestration as a Tuning Point in Controlling Response Dynamics of Signalling NetworksSelection on Network Dynamics Drives Differential Rates of Protein Domain EvolutionModeling Cellular Noise Underlying Heterogeneous Cell Responses in the Epidermal Growth Factor Signaling PathwayNeuronal leucine-rich repeat protein-3 amplifies MAPK activation by epidermal growth factor through a carboxyl-terminal region containing endocytosis motifsCreating and analyzing pathway and protein interaction compendia for modelling signal transduction networksHigh- and low-affinity epidermal growth factor receptor-ligand interactions activate distinct signaling pathwaysPathway databases and tools for their exploitation: benefits, current limitations and challengesNetwork Architecture Predisposes an Enzyme to Either Pharmacologic or Genetic Targeting.Computational modeling of cardiac fibroblasts and fibrosisAn analysis of critical factors for quantitative immunoblotting.
P2860
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P2860
Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors.
description
2002 nî lūn-bûn
@nan
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Computational modeling of the ...... nd internalized EGF receptors.
@ast
Computational modeling of the ...... nd internalized EGF receptors.
@en
Computational modeling of the ...... nd internalized EGF receptors.
@nl
type
label
Computational modeling of the ...... nd internalized EGF receptors.
@ast
Computational modeling of the ...... nd internalized EGF receptors.
@en
Computational modeling of the ...... nd internalized EGF receptors.
@nl
prefLabel
Computational modeling of the ...... nd internalized EGF receptors.
@ast
Computational modeling of the ...... nd internalized EGF receptors.
@en
Computational modeling of the ...... nd internalized EGF receptors.
@nl
P2093
P356
P1433
P1476
Computational modeling of the ...... nd internalized EGF receptors.
@en
P2093
Birgit Schoeberl
Claudia Eichler-Jonsson
Ernst Dieter Gilles
Gertraud Müller
P2888
P304
P356
10.1038/NBT0402-370
P577
2002-04-01T00:00:00Z
P5875
P6179
1045277233