Androgen receptor acetylation governs trans activation and MEKK1-induced apoptosis without affecting in vitro sumoylation and trans-repression function.
about
Negative modulation of androgen receptor transcriptional activity by DaxxStructure and function of steroid receptor AF1 transactivation domains: induction of active conformationsSENP1 enhances androgen receptor-dependent transcription through desumoylation of histone deacetylase 1The cell fate determination factor dachshund inhibits androgen receptor signaling and prostate cancer cellular growthHormonal control of androgen receptor function through SIRT1SF-1 a key player in the development and differentiation of steroidogenic tissuesPathogenic mechanisms and therapeutic strategies in spinobulbar muscular atrophyThe cell fate determination factor DACH1 is expressed in estrogen receptor-alpha-positive breast cancer and represses estrogen receptor-alpha signalingAn acetylation switch modulates the transcriptional activity of estrogen-related receptor alphaTargeted therapy for advanced prostate cancer: inhibition of the PI3K/Akt/mTOR pathwayCharacterisation of a Tip60 specific inhibitor, NU9056, in prostate cancerCell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growthDisruption of a Sirt1-dependent autophagy checkpoint in the prostate results in prostatic intraepithelial neoplasia lesion formationSUMO-specific protease 1 (SENP1) reverses the hormone-augmented SUMOylation of androgen receptor and modulates gene responses in prostate cancer cells.Androgen receptor targets NFkappaB and TSP1 to suppress prostate tumor growth in vivo.Minireview: The versatile roles of lysine deacetylases in steroid receptor signalingThe Role of the Small Ubiquitin-Related Modifier (SUMO) Pathway in Prostate Cancer.Identification of androgen receptor phosphorylation in the primate ovary in vivo.Regulation of androgen receptor activity by the nuclear receptor corepressor SMRT.Intrinsic disorder in the androgen receptor: identification, characterisation and drugability.Nemo-like kinase induces apoptosis and inhibits androgen receptor signaling in prostate cancer cellsSF-1 (nuclear receptor 5A1) activity is activated by cyclic AMP via p300-mediated recruitment to active foci, acetylation, and increased DNA binding.Acetylation of androgen receptor enhances coactivator binding and promotes prostate cancer cell growth.The androgen receptor acetylation site regulates cAMP and AKT but not ERK-induced activity.Activation of p300 histone acetyltransferase activity and acetylation of the androgen receptor by bombesin in prostate cancer cells.Cell fate determination factor Dachshund reprograms breast cancer stem cell function.Acetylation and nuclear receptor actionAcetylation of estrogen receptor alpha by p300 at lysines 266 and 268 enhances the deoxyribonucleic acid binding and transactivation activities of the receptor.Loss of Sirt1 promotes prostatic intraepithelial neoplasia, reduces mitophagy, and delays PARK2 translocation to mitochondriaIncreased acetylation in the DNA-binding domain of TR4 nuclear receptor by the coregulator ARA55 leads to suppression of TR4 transactivationRational therapeutic combinations with histone deacetylase inhibitors for the treatment of cancerCorepressors, nuclear receptors, and epigenetic factors on DNA: a tail of repression.Signaling within a coactivator complex: methylation of SRC-3/AIB1 is a molecular switch for complex disassembly.Androgen receptor splice variants activate androgen receptor target genes and support aberrant prostate cancer cell growth independent of canonical androgen receptor nuclear localization signal.Regulation of androgen receptor signaling in prostate cancer.Androgen receptor serine 81 mediates Pin1 interaction and activity.Histone deacetylase inhibitors (HDACIs): multitargeted anticancer agentsAllosteric modulators of steroid hormone receptors: structural dynamics and gene regulation.ARF represses androgen receptor transactivation in prostate cancer.The functional significance of nuclear receptor acetylation
P2860
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P2860
Androgen receptor acetylation governs trans activation and MEKK1-induced apoptosis without affecting in vitro sumoylation and trans-repression function.
description
2002 nî lūn-bûn
@nan
2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Androgen receptor acetylation ...... and trans-repression function.
@ast
Androgen receptor acetylation ...... and trans-repression function.
@en
Androgen receptor acetylation ...... and trans-repression function.
@nl
type
label
Androgen receptor acetylation ...... and trans-repression function.
@ast
Androgen receptor acetylation ...... and trans-repression function.
@en
Androgen receptor acetylation ...... and trans-repression function.
@nl
prefLabel
Androgen receptor acetylation ...... and trans-repression function.
@ast
Androgen receptor acetylation ...... and trans-repression function.
@en
Androgen receptor acetylation ...... and trans-repression function.
@nl
P2093
P2860
P1476
Androgen receptor acetylation ...... and trans-repression function.
@en
P2093
Chawnshang Chang
Chenguang Wang
Ellis Jaffray
Jorma J Palvimo
Olli A Jänne
Richard G Pestell
Suzanne A W Fuqua
Torsten Hopp
P2860
P304
P356
10.1128/MCB.22.10.3373-3388.2002
P407
P50
P577
2002-05-01T00:00:00Z