10-formyltetrahydrofolate dehydrogenase, one of the major folate enzymes, is down-regulated in tumor tissues and possesses suppressor effects on cancer cells.
about
Gene expression profiling of NF-1-associated and sporadic pilocytic astrocytoma identifies aldehyde dehydrogenase 1 family member L1 (ALDH1L1) as an underexpressed candidate biomarker in aggressive subtypesAcyl carrier protein-specific 4'-phosphopantetheinyl transferase activates 10-formyltetrahydrofolate dehydrogenaseNon-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamilyAldehyde dehydrogenases in cellular responses to oxidative/electrophilic stressALDH1L2 is the mitochondrial homolog of 10-formyltetrahydrofolate dehydrogenaseEnzymatic properties of ALDH1L2, a mitochondrial 10-formyltetrahydrofolate dehydrogenaseAutomated workflow-based exploitation of pathway databases provides new insights into genetic associations of metabolite profilesPhylogeny and evolution of aldehyde dehydrogenase-homologous folate enzymesDifferential patterns of liver proteins in experimental murine hepatosplenic schistosomiasis.Epigenetic alterations of chromosome 3 revealed by NotI-microarrays in clear cell renal cell carcinoma.Aldehyde dehydrogenase 3B1 (ALDH3B1): immunohistochemical tissue distribution and cellular-specific localization in normal and cancerous human tissuesALDH1L1 inhibits cell motility via dephosphorylation of cofilin by PP1 and PP2AProteomic analysis of differentially expressed proteins in peripheral cholangiocarcinoma.A novel tumor suppressor function of glycine N-methyltransferase is independent of its catalytic activity but requires nuclear localizationEpigenetic Silencing of ALDH1L1, a Metabolic Regulator of Cellular Proliferation, in Cancers.Structures of the hydrolase domain of zebrafish 10-formyltetrahydrofolate dehydrogenase and its complexes reveal a complete set of key residues for hydrolysis and product inhibition.Aldehyde dehydrogenase homologous folate enzymes: Evolutionary switch between cytoplasmic and mitochondrial localization.Aberrantly expressed mRNAs and long non-coding RNAs in patients with invasive ductal breast carcinoma: a pilot study.Alcohol intake and folate antagonism via CYP2E1 and ALDH1: effects on oral carcinogenesisActivation of p21-Dependent G1/G2 Arrest in the Absence of DNA Damage as an Antiapoptotic Response to Metabolic Stress.Modular organization of FDH: Exploring the basis of hydrolase catalysisFolate stress induces apoptosis via p53-dependent de novo ceramide synthesis and up-regulation of ceramide synthase 6Dramatic down-regulation of oxidoreductases in human hepatocellular carcinoma hepG2 cells: proteomics and gene ontology unveiling new frontiers in cancer enzymology.FDH: an aldehyde dehydrogenase fusion enzyme in folate metabolism.Production of 1-carbon units from glycine is extensive in healthy men and women.βA3/A1-crystallin is required for proper astrocyte template formation and vascular remodeling in the retinaRole of one-carbon metabolizing pathway genes and gene-nutrient interaction in the risk of non-Hodgkin lymphomaAldehyde dehydrogenase 1 (ALDH1) isoform expression and potential clinical implications in hepatocellular carcinoma.Metabolic Reprogramming by Folate Restriction Leads to a Less Aggressive Cancer Phenotype.Transcriptional landscape of human cancers.Aldh1L1 is expressed by postnatal neural stem cells in vivo.Cancer cells activate p53 in response to 10-formyltetrahydrofolate dehydrogenase expression.10-formyltetrahydrofolate dehydrogenase-induced c-Jun-NH2-kinase pathways diverge at the c-Jun-NH2-kinase substrate level in cells with different p53 status.ALDH1L1 variant rs2276724 and mRNA expression predict post-operative clinical outcomes and are associated with TP53 expression in HBV-related hepatocellular carcinoma.Inducible targeting of CNS astrocytes in Aldh1l1-CreERT2 BAC transgenic mice.The Central Role of Amino Acids in Cancer Redox Homeostasis: Vulnerability Points of the Cancer Redox Code.Volatile metabonomic profiling in urine to detect novel biomarkers for B-cell non-Hodgkin's lymphoma.Deep Sequencing Revealed a CpG Methylation Pattern Associated With ALDH1L1 Suppression in Breast Cancer.
P2860
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P2860
10-formyltetrahydrofolate dehydrogenase, one of the major folate enzymes, is down-regulated in tumor tissues and possesses suppressor effects on cancer cells.
description
2002 nî lūn-bûn
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2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
10-formyltetrahydrofolate dehy ...... essor effects on cancer cells.
@ast
10-formyltetrahydrofolate dehy ...... essor effects on cancer cells.
@en
10-formyltetrahydrofolate dehy ...... essor effects on cancer cells.
@nl
type
label
10-formyltetrahydrofolate dehy ...... essor effects on cancer cells.
@ast
10-formyltetrahydrofolate dehy ...... essor effects on cancer cells.
@en
10-formyltetrahydrofolate dehy ...... essor effects on cancer cells.
@nl
prefLabel
10-formyltetrahydrofolate dehy ...... essor effects on cancer cells.
@ast
10-formyltetrahydrofolate dehy ...... essor effects on cancer cells.
@en
10-formyltetrahydrofolate dehy ...... essor effects on cancer cells.
@nl
P1476
10-formyltetrahydrofolate dehy ...... ressor effects on cancer cells
@en
P2093
Natalia V Oleinik
Sergey A Krupenko
P304
P577
2002-05-01T00:00:00Z