Covalent disulfide-linked anti-CEA diabody allows site-specific conjugation and radiolabeling for tumor targeting applications - Test2 - elhamkhani - TriplyDB

Covalent disulfide-linked anti-CEA diabody allows site-specific conjugation and radiolabeling for tumor targeting applications

Covalent disulfide-linked anti-CEA diabody allows site-specific conjugation and radiolabeling for tumor targeting applications

http://www.wikidata.org/entity/Q34134440

about

Anti-EMP2 diabody blocks epithelial membrane protein 2 (EMP2) and FAK mediated collagen gel contraction in ARPE-19 cells Metabolic biotinylation of recombinant antibody by biotin ligase retained in the endoplasmic reticulum Chemically self-assembled antibody nanorings (CSANs): design and characterization of an anti-CD3 IgM biomimetic Site-Specifically Labeled Immunoconjugates for Molecular Imaging--Part 1: Cysteine Residues and Glycans Exogenous Molecular Probes for Targeted Imaging in Cancer: Focus on Multi-modal Imaging.Fluorescent Image-Guided Surgery with an Anti-Prostate Stem Cell Antigen (PSCA) Diabody Enables Targeted Resection of Mouse Prostate Cancer Xenografts in Real Time.Diabodies targeting epithelial membrane protein 2 reduce tumorigenicity of human endometrial cancer cell lines Design and preclinical evaluation of a 99mTc-labelled diabody of mAb J591 for SPECT imaging of prostate-specific membrane antigen (PSMA).Target mediated disposition of T84.66, a monoclonal anti-CEA antibody: application in the detection of colorectal cancer xenografts ImmunoPET imaging of B-cell lymphoma using 124I-anti-CD20 scFv dimers (diabodies).Tailoring the pharmacokinetics and positron emission tomography imaging properties of anti-carcinoembryonic antigen single-chain Fv-Fc antibody fragments.Enhanced immunoPET of ALCAM-positive colorectal carcinoma using site-specific ⁶⁴Cu-DOTA conjugation.Evaluation of two internalizing carcinoembryonic antigen reporter genes for molecular imaging Noninvasive Imaging of PSMA in prostate tumors with (89)Zr-Labeled huJ591 engineered antibody fragments: the faster alternatives An engineered cysteine-modified diabody for imaging activated leukocyte cell adhesion molecule (ALCAM)-positive tumors.Blockade of epithelial membrane protein 2 (EMP2) abrogates infection of Chlamydia muridarum murine genital infection model Development and Validation of an Immuno-PET Tracer as a Companion Diagnostic Agent for Antibody-Drug Conjugate Therapy to Target the CA6 Epitope Molecular probes for the in vivo imaging of cancer.Advances in immuno-positron emission tomography: antibodies for molecular imaging in oncology Tailoring antibodies for radionuclide delivery.Tumor targeting by a multivalent single-chain Fv (scFv) anti-Lewis Y antibody construct Site-specific, thiol-mediated conjugation of fluorescent probes to cysteine-modified diabodies targeting CD20 or HER2 Radionuclide-Based Cancer Imaging Targeting the Carcinoembryonic Antigen.Evaluation of an anti-p185(HER2) (scFv-C(H)2-C(H)3)2 fragment following radioiodination using two different residualizing labels: SGMIB and IB-Mal-D-GEEEK.Cerenkov Luminescence Imaging as a Modality to Evaluate Antibody-Based PET Radiotracers.Antibody vectors for imaging.Engineered antibodies for molecular imaging of cancer.Chemically-defined camelid antibody bioconjugate for the magnetic resonance imaging of Alzheimer's disease.ImmunoPET Imaging of αvβ6 Expression Using an Engineered Anti-αvβ6 Cys-diabody Site-Specifically Radiolabeled with Cu-64: Considerations for Optimal Imaging with Antibody Fragments.Emerging site-specific bioconjugation strategies for radioimmunotracer development.Minimalist Antibodies and Mimetics: An Update and Recent Applications.ImmunoPET using engineered antibody fragments: fluorine-18 labeled diabodies for same-day imaging.Cys-diabody quantum dot conjugates (immunoQdots) for cancer marker detection.Positive progress in immunoPET--not just a coincidence.

P2860

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P2860

Covalent disulfide-linked anti-CEA diabody allows site-specific conjugation and radiolabeling for tumor targeting applications

http://www.wikidata.org/entity/Q34134440

description

2004 nî lūn-bûn

@nan

2004 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի հունվարին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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name

Covalent disulfide-linked anti ...... r tumor targeting applications

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Covalent disulfide-linked anti ...... r tumor targeting applications

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Covalent disulfide-linked anti ...... r tumor targeting applications

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type

label

Covalent disulfide-linked anti ...... r tumor targeting applications

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Covalent disulfide-linked anti ...... r tumor targeting applications

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Covalent disulfide-linked anti ...... r tumor targeting applications

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Covalent disulfide-linked anti ...... r tumor targeting applications

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Covalent disulfide-linked anti ...... r tumor targeting applications

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Covalent disulfide-linked anti ...... r tumor targeting applications

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P1433

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P2860

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Q34134440-CECD7853-B9C6-45AF-96E9-AFEDB2C4B1A9

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P932

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P1433

Protein Engineering Design and Selection

P1476

Covalent disulfide-linked anti ...... r tumor targeting applications

@en

P2093

Andrew A Raubitschek

http://www.w3.org/2001/XMLSchema#string

Anna M Wu

http://www.w3.org/2001/XMLSchema#string

Chia-Wei Cheung

http://www.w3.org/2001/XMLSchema#string

Gobalakrishnan Sundaresan

http://www.w3.org/2001/XMLSchema#string

John E Shively

http://www.w3.org/2001/XMLSchema#string

Lawrence E Williams

http://www.w3.org/2001/XMLSchema#string

Lin Li

http://www.w3.org/2001/XMLSchema#string

Mark A Sherman

http://www.w3.org/2001/XMLSchema#string

Paul J Yazaki

http://www.w3.org/2001/XMLSchema#string

Sanjiv S Gambhir

http://www.w3.org/2001/XMLSchema#string

P2860

"Diabodies": small bivalent and bispecific antibody fragments

The crystal structure of an anti-CEA scFv diabody assembled from T84.66 scFvs in V(L)-to-V(H) orientation: implications for diabody flexibility

Targeting of liver metastases of colorectal cancer with IgG, F(ab')2, and Fab' anti-carcinoembryonic antigen antibodies labeled with 99mTc: the role of metabolism and kinetics

Secretion of immunoglobulin M assembly intermediates in the presence of reducing agents

Preparation of monoclonal antibodies: strategies and procedures.

Site-specific covalent modification of monoclonal antibodies: in vitro and in vivo evaluations.

Performance evaluation of microPET: a high-resolution lutetium oxyorthosilicate PET scanner for animal imaging.

Clinical evidence of efficient tumor targeting based on single-chain Fv antibody selected from a combinatorial library.

High-resolution microPET imaging of carcinoembryonic antigen-positive xenografts by using a copper-64-labeled engineered antibody fragment

Domain motions in phosphoglycerate kinase: determination of interdomain distance distributions by site-specific labeling and time-resolved fluorescence energy transfer

P304

21-27

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1093/PROTEIN/GZH009

http://www.w3.org/2001/XMLSchema#string

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

17

http://www.w3.org/2001/XMLSchema#string

P577

2004-01-01T00:00:00Z

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P5875

7254873

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P698

14985534

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P932

4154813

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