Evolution of transcription factor binding sites in Mammalian gene regulatory regions: conservation and turnover.
about
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot projectEarly history of mammals is elucidated with the ENCODE multiple species sequencing dataThe diploid genome sequence of an individual humanChromatin landscape dictates HSF binding to target DNA elementsPPARG binding landscapes in macrophages suggest a genome-wide contribution of PU.1 to divergent PPARG binding in human and mouse8.2% of the Human genome is constrained: variation in rates of turnover across functional element classes in the human lineageDe novo genesis of enhancers in vertebratesFast-evolving noncoding sequences in the human genomeA catalog of neutral and deleterious polymorphism in yeastDoes positive selection drive transcription factor binding site turnover? A test with Drosophila cis-regulatory modulesWhat fraction of the human genome is functional?Five-vertebrate ChIP-seq reveals the evolutionary dynamics of transcription factor bindingDefining functional DNA elements in the human genomeGenome of the marsupial Monodelphis domestica reveals innovation in non-coding sequencesHuman embryonic stem cell-derived neurons as a tool for studying neuroprotection and neurodegenerationZinc-finger domains of the transcriptional repressor KLF15 bind multiple sites in rhodopsin and IRBP promoters including the CRS-1 and G-rich repressor elementsMONKEY: identifying conserved transcription-factor binding sites in multiple alignments using a binding site-specific evolutionary modelDistinct class of putative "non-conserved" promoters in humans: comparative studies of alternative promoters of human and mouse genesA model of the statistical power of comparative genome sequence analysisConservation of regulatory elements between two species of DrosophilaThe architecture of mammalian ribosomal protein promotersPosition specific variation in the rate of evolution in transcription factor binding sitesConservation and evolution of cis-regulatory systems in ascomycete fungioPOSSUM: identification of over-represented transcription factor binding sites in co-expressed genes.ABS: a database of Annotated regulatory Binding Sites from orthologous promoters.Decoding the non-coding genome: elucidating genetic risk outside the coding genomeEvolutionary and functional analysis of the tailless enhancer in Musca domestica and Drosophila melanogasterBinding site turnover produces pervasive quantitative changes in transcription factor binding between closely related Drosophila speciesQuantitative system drift compensates for altered maternal inputs to the gap gene network of the scuttle fly Megaselia abditaFunctional characterization of motif sequences under purifying selectionMISCORE: a new scoring function for characterizing DNA regulatory motifs in promoter sequencesWaves of retrotransposon expansion remodel genome organization and CTCF binding in multiple mammalian lineagesMassive turnover of functional sequence in human and other mammalian genomesSystematic identification of cis-regulatory sequences active in mouse and human embryonic stem cellsDivergent evolution of human p53 binding sites: cell cycle versus apoptosisDetection of functional DNA motifs via statistical over-representationMassively parallel cis-regulatory analysis in the mammalian central nervous systemLength polymorphism and head shape association among genes with polyglutamine repeats in the stalk-eyed fly, Teleopsis dalmanni.Genomic structure and expression of uncoupling protein 2 genes in rainbow trout (Oncorhynchus mykiss)Statistical tests for natural selection on regulatory regions based on the strength of transcription factor binding sites.
P2860
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P2860
Evolution of transcription factor binding sites in Mammalian gene regulatory regions: conservation and turnover.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Evolution of transcription fac ...... ns: conservation and turnover.
@ast
Evolution of transcription fac ...... ns: conservation and turnover.
@en
Evolution of transcription fac ...... ns: conservation and turnover.
@nl
type
label
Evolution of transcription fac ...... ns: conservation and turnover.
@ast
Evolution of transcription fac ...... ns: conservation and turnover.
@en
Evolution of transcription fac ...... ns: conservation and turnover.
@nl
prefLabel
Evolution of transcription fac ...... ns: conservation and turnover.
@ast
Evolution of transcription fac ...... ns: conservation and turnover.
@en
Evolution of transcription fac ...... ns: conservation and turnover.
@nl
P2860
P1476
Evolution of transcription fac ...... ns: conservation and turnover.
@en
P2093
Andrew G Clark
Emmanouil T Dermitzakis
P2860
P304
P356
10.1093/OXFORDJOURNALS.MOLBEV.A004169
P577
2002-07-01T00:00:00Z