Controlled human malaria infection of Tanzanians by intradermal injection of aseptic, purified, cryopreserved Plasmodium falciparum sporozoites. - Test2 - elhamkhani - TriplyDB

Controlled human malaria infection of Tanzanians by intradermal injection of aseptic, purified, cryopreserved Plasmodium falciparum sporozoites.

Controlled human malaria infection of Tanzanians by intradermal injection of aseptic, purified, cryopreserved Plasmodium falciparum sporozoites.

http://www.wikidata.org/entity/Q34138437

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Plasmodium vivax Controlled Human Malaria Infection - Progress and Prospects The March Toward Malaria Vaccines Engineering of Genetically Arrested Parasites (GAPs) For a Precision Malaria Vaccine Evaluating controlled human malaria infection in Kenyan adults with varying degrees of prior exposure to Plasmodium falciparum using sporozoites administered by intramuscular injection Increased sample volume and use of quantitative reverse-transcription PCR can improve prediction of liver-to-blood inoculum size in controlled human malaria infection studies Red blood cell indices and prevalence of hemoglobinopathies and glucose 6 phosphate dehydrogenase deficiencies in male Tanzanian residents of Dar es Salaam.Direct venous inoculation of Plasmodium falciparum sporozoites for controlled human malaria infection: a dose-finding trial in two centres.Development of cultured Plasmodium falciparum blood-stage malaria cell banks for early phase in vivo clinical trial assessment of anti-malaria drugs and vaccines.Impact of malaria preexposure on antiparasite cellular and humoral immune responses after controlled human malaria infection.Lessons learnt from the first controlled human malaria infection study conducted in Nairobi, Kenya Robust, reproducible, industrialized, standard membrane feeding assay for assessing the transmission blocking activity of vaccines and drugs against Plasmodium falciparum Controlled human malaria infection by intramuscular and direct venous inoculation of cryopreserved Plasmodium falciparum sporozoites in malaria-naïve volunteers: effect of injection volume and dose on infectivity rates Safety and Reproducibility of a Clinical Trial System Using Induced Blood Stage Plasmodium vivax Infection and Its Potential as a Model to Evaluate Malaria Transmission Optimizing Intradermal Administration of Cryopreserved Plasmodium falciparum Sporozoites in Controlled Human Malaria Infection.Large screen approaches to identify novel malaria vaccine candidates.Safety, Immunogenicity, and Protective Efficacy of Intradermal Immunization with Aseptic, Purified, Cryopreserved Plasmodium falciparum Sporozoites in Volunteers Under Chloroquine Prophylaxis: A Randomized Controlled Trial.Demonstration of the Blood-Stage Plasmodium falciparum Controlled Human Malaria Infection Model to Assess Efficacy of the P. falciparum Apical Membrane Antigen 1 Vaccine, FMP2.1/AS01 Current therapies and future possibilities for drug development against liver-stage malaria.Mosquito bite immunization with radiation-attenuated Plasmodium falciparum sporozoites: safety, tolerability, protective efficacy and humoral immunogenicity Infectivity of Plasmodium falciparum in Malaria-Naive Individuals Is Related to Knob Expression and Cytoadherence of the Parasite.Changes in Serological Immunology Measures in UK and Kenyan Adults Post-controlled Human Malaria Infection.Progress with Plasmodium falciparum sporozoite (PfSPZ)-based malaria vaccines.The march toward malaria vaccines.Controlled Human Malaria Infection Leads to Long-Lasting Changes in Innate and Innate-like Lymphocyte Populations.Development of whole sporozoite malaria vaccines.Development of replication-deficient adenovirus malaria vaccines.Considerations for Comprehensive Analyses of Sporozoite-Based Controlled Human Malaria Infection Studies.A framework for Controlled Human Infection Model (CHIM) studies in Malawi: Report of a Wellcome Trust workshop on CHIM in Low Income Countries held in Blantyre, Malawi.Development & licensing of first ever vaccine against malaria.The ability to inoculate purified malaria sporozoites will accelerate vaccine and drug discovery.Advancing Global Health through Development and Clinical Trials Partnerships: A Randomized, Placebo-Controlled, Double-Blind Assessment of Safety, Tolerability, and Immunogenicity of PfSPZ Vaccine for Malaria in Healthy Equatoguinean Men.Controlled Human Malaria Infection: Applications, Advances and Challenges.Impact of Sickle Cell Trait and Naturally Acquired Immunity on Uncomplicated Malaria after Controlled Human Malaria Infection in Adults in Gabon.What goes around comes around: modeling malaria transmission from humans back to mosquitos.Ethical considerations in Controlled Human Malaria Infection studies in low resource settings: Experiences and perceptions of study participants in a malaria Challenge study in Kenya.Acceptability of a herd immunity-focused, transmission-blocking malaria vaccine in malaria-endemic communities in the Peruvian Amazon: an exploratory study.Whole blood transcriptome changes following controlled human malaria infection in malaria pre-exposed volunteers correlate with parasite prepatent period.Safety, Immunogenicity, and Protective Efficacy against Controlled Human Malaria Infection of Sporozoite Vaccine in Tanzanian Adults Controlled Human Infections As a Tool to Reduce Uncertainty in Clinical Vaccine Development

P2860

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P2860

Controlled human malaria infection of Tanzanians by intradermal injection of aseptic, purified, cryopreserved Plasmodium falciparum sporozoites.

http://www.wikidata.org/entity/Q34138437

description

2014 nî lūn-bûn

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2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2014 թվականի հուլիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Controlled human malaria infec ...... modium falciparum sporozoites.

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American Journal of Tropical Medicine and Hygiene

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Controlled human malaria infec ...... modium falciparum sporozoites.

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Adam Ruben

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Ali Hamad

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Ali Mohammed

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Alwisa Urassa

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Anita Manoj

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Anusha Gunasekera

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B Kim Lee Sim

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Beatus Simon

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Christopher Plowe

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Claudia A Daubenberger

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P2860

Development of a metabolically active, non-replicating sporozoite vaccine to prevent Plasmodium falciparum malaria

Multiple independent introductions of Plasmodium falciparum in South America

South American Plasmodium falciparum after the malaria eradication era: clonal population expansion and survival of the fittest hybrids

Comparison of clinical and parasitological data from controlled human malaria infection trials

Plasmodium falciparum malaria challenge by the bite of aseptic Anopheles stephensi mosquitoes: results of a randomized infectivity trial

α-thalassaemia

Clinical manifestations of Plasmodium falciparum malaria experimentally induced by mosquito challenge.

A cohort study of Plasmodium falciparum infection dynamics in Western Kenya Highlands.

Live attenuated malaria vaccine designed to protect through hepatic CD8⁺ T cell immunity.

Protection against malaria by intravenous immunization with a nonreplicating sporozoite vaccine.

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471-480

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10.4269/AJTMH.14-0119

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3

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91

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Christopher V Plowe

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Robert W Sauerwein

Stephen L Hoffman

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2014-07-28T00:00:00Z

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264633995

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25070995

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cryopreservation

Plasmodium falciparum

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4155546

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