BRCA2 and Smad3 synergize in regulation of gene transcription.
about
Proteomics-based identification of proteins interacting with Smad3: SREBP-2 forms a complex with Smad3 and inhibits its transcriptional activityBRCA2 is required for neurogenesis and suppression of medulloblastomaEvidence for SMAD3 as a modifier of breast cancer risk in BRCA2 mutation carriers.The breast cancer susceptibility genes (BRCA) in breast and ovarian cancers.Two major Smad pathways in TGF-beta superfamily signalling.BRCA2 cooperates with histone acetyltransferases in androgen receptor-mediated transcription.Cyclin-dependent kinase 4-mediated phosphorylation inhibits Smad3 activity in cyclin D-overexpressing breast cancer cells.TGF-β Inhibition Rescues Hematopoietic Stem Cell Defects and Bone Marrow Failure in Fanconi Anemia.TGF-β reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24- cancer cells.Up-regulation of the interferon-related genes in BRCA2 knockout epithelial cells.Fanconi Anemia Proteins Function in Mitophagy and ImmunityFull in-frame exon 3 skipping of BRCA2 confers high risk of breast and/or ovarian cancer.
P2860
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P2860
BRCA2 and Smad3 synergize in regulation of gene transcription.
description
2002 nî lūn-bûn
@nan
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
BRCA2 and Smad3 synergize in regulation of gene transcription.
@ast
BRCA2 and Smad3 synergize in regulation of gene transcription.
@en
BRCA2 and Smad3 synergize in regulation of gene transcription.
@nl
type
label
BRCA2 and Smad3 synergize in regulation of gene transcription.
@ast
BRCA2 and Smad3 synergize in regulation of gene transcription.
@en
BRCA2 and Smad3 synergize in regulation of gene transcription.
@nl
prefLabel
BRCA2 and Smad3 synergize in regulation of gene transcription.
@ast
BRCA2 and Smad3 synergize in regulation of gene transcription.
@en
BRCA2 and Smad3 synergize in regulation of gene transcription.
@nl
P2093
P2860
P356
P1433
P1476
BRCA2 and Smad3 synergize in regulation of gene transcription.
@en
P2093
Carl-Henrik Heldin
Ihor Yakymovych
Mariya Yakymovych
Olena Preobrazhenska
Rostyslav Stoika
Serhiy Souchelnytskyi
Takashi Kanamoto
P2860
P2888
P304
P356
10.1038/SJ.ONC.1205732
P407
P577
2002-08-01T00:00:00Z
P5875
P6179
1033243837