Genomic tagging reveals a random association of endogenous PtdIns5P 4-kinases IIalpha and IIbeta and a partial nuclear localization of the IIalpha isoform.
about
Phosphoinositides: tiny lipids with giant impact on cell regulationPIP kinases define PI4,5P₂signaling specificity by association with effectorsEvolutionarily conserved structural changes in phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) isoforms are responsible for differences in enzyme activity and localizationThe function of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) explored using a specific inhibitor that targets the PI5P-binding siteThe emerging role of PtdIns5P: another signalling phosphoinositide takes its place.SILAC-iPAC: a quantitative method for distinguishing genuine from non-specific components of protein complexes by parallel affinity capture.Exploring phosphatidylinositol 5-phosphate 4-kinase function.Deletion of the gene Pip4k2c, a novel phosphatidylinositol kinase, results in hyperactivation of the immune systemIn B cells, phosphatidylinositol 5-phosphate 4-kinase-α synthesizes PI(4,5)P2 to impact mTORC2 and Akt signalingNuclear phosphoinositides and their roles in cell biology and disease.The basal transcription complex component TAF3 transduces changes in nuclear phosphoinositides into transcriptional output.Regulation of phosphatidylinositol-5-phosphate signaling by Pin1 determines sensitivity to oxidative stress.Localization and projected role of phosphatidylinositol 4-kinases IIα and IIβ in inositol 1,4,5-trisphosphate-sensitive nucleoplasmic Ca²⁺ store vesicles.Inositides--confusion and clarification in Shangri-La.Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein.PIP4K2A regulates intracellular cholesterol transport through modulating PI(4,5)P2 homeostasis.PIPKIIα is widely expressed in hematopoietic-derived cells and may play a role in the expression of alpha- and gamma-globins in K562 cells.
P2860
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P2860
Genomic tagging reveals a random association of endogenous PtdIns5P 4-kinases IIalpha and IIbeta and a partial nuclear localization of the IIalpha isoform.
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Genomic tagging reveals a rand ...... zation of the IIalpha isoform.
@ast
Genomic tagging reveals a rand ...... zation of the IIalpha isoform.
@en
Genomic tagging reveals a rand ...... zation of the IIalpha isoform.
@nl
type
label
Genomic tagging reveals a rand ...... zation of the IIalpha isoform.
@ast
Genomic tagging reveals a rand ...... zation of the IIalpha isoform.
@en
Genomic tagging reveals a rand ...... zation of the IIalpha isoform.
@nl
prefLabel
Genomic tagging reveals a rand ...... zation of the IIalpha isoform.
@ast
Genomic tagging reveals a rand ...... zation of the IIalpha isoform.
@en
Genomic tagging reveals a rand ...... zation of the IIalpha isoform.
@nl
P2093
P2860
P356
P1433
P1476
Genomic tagging reveals a rand ...... zation of the IIalpha isoform.
@en
P2093
Andrew J Letcher
Jonathan H Clarke
Jonathan P Richardson
Kathryn S Lilley
Minchuan Wang
Nicholas J Bond
Robin F Irvine
P2860
P304
P356
10.1042/BJ20100340
P407
P577
2010-09-01T00:00:00Z