Transcriptional regulation of human Rev-erbalpha gene expression by the orphan nuclear receptor retinoic acid-related orphan receptor alpha. - Test2 - elhamkhani - TriplyDB

Transcriptional regulation of human Rev-erbalpha gene expression by the orphan nuclear receptor retinoic acid-related orphan receptor alpha.

Transcriptional regulation of human Rev-erbalpha gene expression by the orphan nuclear receptor retinoic acid-related orphan receptor alpha.

http://www.wikidata.org/entity/Q34154293

about

The nuclear receptor Rev-erbalpha is a liver X receptor (LXR) target gene driving a negative feedback loop on select LXR-induced pathways in human macrophages Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta.Potential roles of ROR-alpha in cardiovascular endocrinology.Characterization of the core mammalian clock component, NPAS2, as a REV-ERBalpha/RORalpha target gene Circadian rhythms in liver metabolism and disease RORγ directly regulates the circadian expression of clock genes and downstream targets in vivo The orphan nuclear receptor RORalpha restrains adipocyte differentiation through a reduction of C/EBPbeta activity and perilipin gene expression Retinoic acid actions through mammalian nuclear receptors.Interaction between retinoid acid receptor-related orphan receptor alpha (RORA) and neuropeptide S receptor 1 (NPSR1) in asthma.Implication of the F-Box Protein FBXL21 in circadian pacemaker function in mammals.Rev-erbalpha2 mRNA encodes a stable protein with a potential role in circadian clock regulation Nuclear hormone receptors for heme: REV-ERBalpha and REV-ERBbeta are ligand-regulated components of the mammalian clock.A second class of nuclear receptors for oxysterols: Regulation of RORalpha and RORgamma activity by 24S-hydroxycholesterol (cerebrosterol)Control of gene expression by the retinoic acid-related orphan receptor alpha in HepG2 human hepatoma cells.Rev-erbalpha upregulates NF-kappaB-responsive genes in vascular smooth muscle cells.The orphan receptor Rev-erbalpha gene is a target of the circadian clock pacemaker.The orphan Rev-erb nuclear receptors: a link between metabolism, circadian rhythm and inflammation?Homozygous staggerer (sg/sg) mice display improved insulin sensitivity and enhanced glucose uptake in skeletal muscle Identification of SR3335 (ML-176): a synthetic RORα selective inverse agonist Retinoic acid-related orphan receptor γ directly regulates neuronal PAS domain protein 2 transcription in vivo.Nitric oxide coordinates metabolism, growth, and development via the nuclear receptor E75.Adopting new orphans into the family of metabolic regulators Nuclear receptors, metabolism, and the circadian clock.The nuclear receptors Rev-erbs and RORs integrate circadian rhythms and metabolism.How nuclear receptors tell time.RORα and RORγ expression inversely correlates with human melanoma progression.The circadian clock in oral health and diseases Nuclear receptor Rev-erbα: up, down, and all around.CYP19A1, MIF and ABCA1 genes are targets of the RORα in monocyte and endothelial cells.Inhibition of adipocyte differentiation by RORalpha.Different mechanisms of adjustment to a change of the photoperiod in the suprachiasmatic and liver circadian clocks.Liver-specific deletion of RORα aggravates diet-induced nonalcoholic steatohepatitis by inducing mitochondrial dysfunction.RORA; EP300; PPARGC1A bind NR1D1 gene Postnatal ontogenesis of the circadian clock within the rat liver.Distinct roles for REV-ERBα and REV-ERBβ in oxidative capacity and mitochondrial biogenesis in skeletal muscle.

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Transcriptional regulation of human Rev-erbalpha gene expression by the orphan nuclear receptor retinoic acid-related orphan receptor alpha.

http://www.wikidata.org/entity/Q34154293

description

2002 nî lūn-bûn

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2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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Transcriptional regulation of ...... related orphan receptor alpha.

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Transcriptional regulation of ...... related orphan receptor alpha.

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Transcriptional regulation of ...... related orphan receptor alpha.

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Caroline Duval

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Eric Raspè

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Gisèle Mautino

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Hélène Duez

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Jamila Fruchart

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Olivier Barbier

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P2860

Exogenous expression of a dominant negative RORalpha1 vector in muscle cells impairs differentiation: RORalpha1 directly interacts with p300 and myoD

Transcriptional regulation of apolipoprotein C-III gene expression by the orphan nuclear receptor RORalpha

The orphan nuclear receptor ROR alpha is a negative regulator of the inflammatory response

A functional Rev-erb alpha responsive element located in the human Rev-erb alpha promoter mediates a repressing activity

The nuclear receptors peroxisome proliferator-activated receptor alpha and Rev-erbalpha mediate the species-specific regulation of apolipoprotein A-I expression by fibrates

Isoform-specific amino-terminal domains dictate DNA-binding properties of ROR alpha, a novel family of orphan hormone nuclear receptors

Two receptor interaction domains in the corepressor, N-CoR/RIP13, are required for an efficient interaction with Rev-erbA alpha and RVR: physical association is dependent on the E region of the orphan receptors

Genomic organization of the human thyroid hormone receptor alpha (c-erbA-1) gene

Cloning and characterization of a corepressor and potential component of the nuclear hormone receptor repression complex

In vitro and in vivo evidence for orphan nuclear receptor RORalpha function in bone metabolism

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10.1074/JBC.M206215200

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51

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277

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Jean-Charles Fruchart

Coralie Fontaine

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2002-10-10T00:00:00Z

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12377782

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