A functional screen for recovery of 4'-phosphopantetheinyl transferase and associated natural product biosynthesis genes from metagenome libraries.
about
Targeted metagenomics as a tool to tap into marine natural product diversity for the discovery and production of drug candidatesFlavoenzymes: versatile catalysts in biosynthetic pathwaysThe phosphopantetheinyl transferases: catalysis of a post-translational modification crucial for lifeMining the metabiome: identifying novel natural products from microbial communities.Metagenomic small molecule discovery methods.Selective enrichment of environmental DNA libraries for genes encoding nonribosomal peptides and polyketides by phosphopantetheine transferase-dependent complementation of siderophore biosynthesis.Meta-omic characterization of prokaryotic gene clusters for natural product biosynthesis.Interplay between siderophores and colibactin genotoxin biosynthetic pathways in Escherichia coliPortability of the thiolation domain in recombinant pyoverdine non-ribosomal peptide synthetases.Identification of antibacterial peptides from endophytic microbiome.Using natural products for drug discovery: the impact of the genomics era.Bioprospecting potential of the soil metagenome: novel enzymes and bioactivitiesReporter-based screening and selection of enzymes.Genetic manipulation of non-ribosomal peptide synthetases to generate novel bioactive peptide products.An efficient blue-white screening based gene inactivation system for Streptomyces.Biosynthesis of novel Pyoverdines by domain substitution in a nonribosomal peptide synthetase of Pseudomonas aeruginosa.A sensitive single-enzyme assay system using the non-ribosomal peptide synthetase BpsA for measurement of L-glutamine in biological samplesAn external substrate-free blue/white screening system in Escherichia coli.Identification of biosynthetic gene clusters from metagenomic libraries using PPTase complementation in a Streptomyces host.Creating functional engineered variants of the single-module non-ribosomal peptide synthetase IndC by T domain exchange.Concepts and Methods to Access Novel Antibiotics from Actinomycetes.Marine metagenomics, a valuable tool for enzymes and bioactive compounds discovery
P2860
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P2860
A functional screen for recovery of 4'-phosphopantetheinyl transferase and associated natural product biosynthesis genes from metagenome libraries.
description
2012 nî lūn-bûn
@nan
2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
A functional screen for recove ...... nes from metagenome libraries.
@ast
A functional screen for recove ...... nes from metagenome libraries.
@en
A functional screen for recove ...... nes from metagenome libraries.
@nl
type
label
A functional screen for recove ...... nes from metagenome libraries.
@ast
A functional screen for recove ...... nes from metagenome libraries.
@en
A functional screen for recove ...... nes from metagenome libraries.
@nl
prefLabel
A functional screen for recove ...... nes from metagenome libraries.
@ast
A functional screen for recove ...... nes from metagenome libraries.
@en
A functional screen for recove ...... nes from metagenome libraries.
@nl
P2860
P1476
A functional screen for recove ...... enes from metagenome libraries
@en
P2093
P2860
P304
P356
10.1111/J.1462-2920.2012.02699.X
P577
2012-02-22T00:00:00Z