Evidence for degenerative and regenerative changes in neostriatal spiny neurons in Huntington's disease.
about
Ubiquitin-proteasome system involvement in Huntington's diseaseCharacterization of a brain-enriched chaperone, MRJ, that inhibits Huntingtin aggregation and toxicity independentlyPsychomotor retardation in depression: biological underpinnings, measurement, and treatmentThe Response to Oxidative DNA Damage in Neurons: Mechanisms and DiseaseNucleolar dysfunction in Huntington's diseaseHuntington's disease: the past, present, and future search for disease modifiers.Disease-toxicant interactions in manganese exposed Huntington disease mice: early changes in striatal neuron morphology and dopamine metabolismEffects of deletion of mutant huntingtin in steroidogenic factor 1 neurons on the psychiatric and metabolic phenotype in the BACHD mouse model of Huntington diseaseDrosophila as an In Vivo Model for Human Neurodegenerative DiseaseCalpain and STriatal-Enriched protein tyrosine phosphatase (STEP) activation contribute to extrasynaptic NMDA receptor localization in a Huntington's disease mouse modelHuntingtin and its role in neuronal degenerationEpigenetic mechanisms of neurodegeneration in Huntington's diseaseN-Acetylcysteine improves mitochondrial function and ameliorates behavioral deficits in the R6/1 mouse model of Huntington's diseaseEvaluation of histone deacetylases as drug targets in Huntington's disease models. Study of HDACs in brain tissues from R6/2 and CAG140 knock-in HD mouse models and human patients and in a neuronal HD cell modelInhibition of calpain cleavage of huntingtin reduces toxicity: accumulation of calpain/caspase fragments in the nucleusHAP1-huntingtin interactions do not contribute to the molecular pathology in Huntington's disease transgenic miceSelective frontoinsular von Economo neuron and fork cell loss in early behavioral variant frontotemporal dementia.Neurodegenerative diseases target large-scale human brain networksThe basal ganglia in perceptual timing: timing performance in Multiple System Atrophy and Huntington's disease.Mouse models of Huntington's disease and methodological considerations for therapeutic trials.Molecular insights into Alzheimer's disease.HAP1 can sequester a subset of TBP in cytoplasmic inclusions via specific interaction with the conserved TBP(CORE).Conformational targeting of fibrillar polyglutamine proteins in live cells escalates aggregation and cytotoxicity.Dopamine D2 receptor stimulation potentiates PolyQ-Huntingtin-induced mouse striatal neuron dysfunctions via Rho/ROCK-II activationProtection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription.Modeling Huntington disease in yeast: perspectives and future directions.Topological length of white matter connections predicts their rate of atrophy in premanifest Huntington's disease.Huntington's disease: silencing a brutal killer.Differential loss of striatal projection neurons in Huntington disease.A small molecule p75NTR ligand normalizes signalling and reduces Huntington's disease phenotypes in R6/2 and BACHD mice.Decreased Lin7b expression in layer 5 pyramidal neurons may contribute to impaired corticostriatal connectivity in huntington disease.Are there multiple pathways in the pathogenesis of Huntington's disease?Polyglutamine pathogenesis.Huntington disease models and human neuropathology: similarities and differencesMicroglial Activation in the Pathogenesis of Huntington's Disease.Selective vulnerability of late-generated dopaminergic neurons of the substantia nigra in weaver mutant mice.The striatofugal fiber system in primates: a reevaluation of its organization based on single-axon tracing studies.Developmental regulation and neuroprotective effects of striatal tonic GABAA currentsProteostasis in striatal cells and selective neurodegeneration in Huntington's disease.Neuroprotective potential of CB1 receptor agonists in an in vitro model of Huntington's disease.
P2860
Q21129327-1275C7C8-3417-4B29-BBF1-DB215380137FQ24292471-34F11277-AC2E-4055-B471-0F20051D8BEFQ24629825-10109C7F-89D8-480F-9F20-61F0E1B88EEBQ26768287-373B657A-2382-4C74-99E2-7292F6322400Q26822451-4E823076-53D7-47BD-BDCF-DD5CF4C8E5FCQ26830039-F6E21133-B765-4B23-B451-0CC71A93D5FBQ27309160-8C7DD8F9-BC5C-49B6-A9DA-34B2052E7BC7Q27346849-3A4C91B6-F86F-4A56-B3F4-E89B47941F4DQ28088777-A85E2D7A-8F3E-40A9-9F2B-47A758577B45Q28265056-92434C01-FC43-47B7-9AAE-D7A20BD1244BQ28281434-1673CB7F-DB6E-4F05-97FD-924E397A6912Q28297936-0F9FEFBD-55A1-4DCA-9B80-A193B21C7225Q28387085-CFC9F2D5-BA31-4A2C-9924-80FD7F67921DQ28475537-45FA3F72-E356-4C47-8C0F-7160F42611C9Q28505053-776F25A6-7AAD-4B70-8B57-6CA65EC7FE04Q28512691-FB7ED623-7AFE-42B0-9CD3-2E73C909BFEAQ28732862-90DC10BB-0D17-4A1E-B728-15D8DB86F4BCQ29614723-003539A6-F846-4B7D-AD50-8DAC98FB6656Q30443884-71ADAADA-A2FF-4CFE-BE5C-A06536E33E37Q30481208-248FC382-A71A-4113-8AD7-DA80F084A858Q31058930-006A861A-3CD6-45B1-A53F-BAF6FCBEC41DQ33299019-EBCE123E-7E13-47D6-92DE-C0CB83D88706Q33459255-4FBBC99C-2A67-4FC2-8C40-596CD5A454E1Q33519066-D257E760-1615-4152-9B7B-401F5FDA850CQ33551416-0EC44CC7-59F0-454D-8880-F665C80987B0Q33575494-42A6D202-962F-4146-B6AB-C89F4D1F3C15Q33579030-4DCD9FD4-913F-4E63-B1AD-7F3CB14AB75CQ33586461-EADF208C-FE40-4524-93DD-7483A4DE7D24Q33637273-76ABC24D-DF9E-40F2-8D2C-FCBE300AA5D7Q33640604-2249EFF8-2578-45A1-9CA3-CA5DB2434477Q33663335-9E5D2A72-CB86-481D-92AC-4DAFA4E9D186Q33703905-F87D93C7-02F8-4383-865C-B7F612A102E5Q33703910-EDDB0E72-1B48-48BE-8721-AF471ECF2A2EQ33760994-0AF18A5D-3C9E-4B13-ABF8-368CD7CC56D0Q33809556-304BA0E7-F668-463D-ABA9-8A9AFB64FE16Q33887862-22835D1B-DCAB-41EB-B675-D6F89016D040Q33920107-28AF6920-C849-4663-A735-398B1021982FQ34007247-F47B8EC5-4B01-4E52-B1AB-1C4A214A7298Q34014433-BF71E3F1-EF81-473D-AF45-84B33F5734CCQ34098292-EC5068B3-B0FD-4AAA-9ADD-5B04714FB124
P2860
Evidence for degenerative and regenerative changes in neostriatal spiny neurons in Huntington's disease.
description
1985 nî lūn-bûn
@nan
1985 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1985 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1985年の論文
@ja
1985年論文
@yue
1985年論文
@zh-hant
1985年論文
@zh-hk
1985年論文
@zh-mo
1985年論文
@zh-tw
1985年论文
@wuu
name
Evidence for degenerative and ...... urons in Huntington's disease.
@ast
Evidence for degenerative and ...... urons in Huntington's disease.
@en
Evidence for degenerative and ...... urons in Huntington's disease.
@nl
type
label
Evidence for degenerative and ...... urons in Huntington's disease.
@ast
Evidence for degenerative and ...... urons in Huntington's disease.
@en
Evidence for degenerative and ...... urons in Huntington's disease.
@nl
prefLabel
Evidence for degenerative and ...... urons in Huntington's disease.
@ast
Evidence for degenerative and ...... urons in Huntington's disease.
@en
Evidence for degenerative and ...... urons in Huntington's disease.
@nl
P2093
P356
P1433
P1476
Evidence for degenerative and ...... urons in Huntington's disease.
@en
P2093
DiFiglia M
Graveland GA
Williams RS
P304
P356
10.1126/SCIENCE.3155875
P407
P577
1985-02-01T00:00:00Z