Celastrus-derived celastrol suppresses autoimmune arthritis by modulating antigen-induced cellular and humoral effector responses
about
A cytokine-centric view of the pathogenesis and treatment of autoimmune arthritisDecrease of CD68 Synovial Macrophages in Celastrol Treated Arthritic RatsCelastrol attenuates inflammatory and neuropathic pain mediated by cannabinoid receptor type 2.Myxobacteria versus sponge-derived alkaloids: the bengamide family identified as potent immune modulating agents by scrutiny of LC-MS/ELSD librariesRelease of Ca2+ from the endoplasmic reticulum and its subsequent influx into mitochondria trigger celastrol-induced paraptosis in cancer cells.Celastrol stimulates hypoxia-inducible factor-1 activity in tumor cells by initiating the ROS/Akt/p70S6K signaling pathway and enhancing hypoxia-inducible factor-1α protein synthesis.Novel Curcumin Diclofenac Conjugate Enhanced Curcumin Bioavailability and Efficacy in Streptococcal Cell Wall-induced ArthritisCelastrol inhibits lipopolysaccharide-stimulated rheumatoid fibroblast-like synoviocyte invasion through suppression of TLR4/NF-κB-mediated matrix metalloproteinase-9 expression.Anti-invasive effects of Celastrus Orbiculatus extract on interleukin-1 beta and tumour necrosis factor-alpha combination-stimulated fibroblast-like synoviocytes.Celastrol, a Chinese herbal compound, controls autoimmune inflammation by altering the balance of pathogenic and regulatory T cells in the target organ.Celastrol supports survival of retinal ganglion cells injured by optic nerve crush.Modified huo-luo-xiao-ling dan suppresses adjuvant arthritis by inhibiting chemokines and matrix-degrading enzymes.Medicinal plants with potential anti-arthritic activityCelastrus and its bioactive celastrol protect against bone damage in autoimmune arthritis by modulating osteoimmune cross-talkMicroarray-based gene expression profiling reveals the mediators and pathways involved in the anti-arthritic activity of Celastrus-derived Celastrol.Suppression of autoimmune arthritis by Celastrus-derived Celastrol through modulation of pro-inflammatory chemokinesCelastrol Ameliorates Ulcerative Colitis-Related Colorectal Cancer in Mice via Suppressing Inflammatory Responses and Epithelial-Mesenchymal Transition.Lipophilic stinging nettle extracts possess potent anti-inflammatory activity, are not cytotoxic and may be superior to traditional tinctures for treating inflammatory disorders.Kinetics and interplay of mediators of inflammation-induced bone damage in the course of adjuvant arthritisCelastrus treatment modulates antigen-induced gene expression in lymphoid cells of arthritic ratsComparative antigen-induced gene expression profiles unveil novel aspects of susceptibility/resistance to adjuvant arthritis in ratsMetabolomics profiles delineate uridine deficiency contributes to mitochondria-mediated apoptosis induced by celastrol in human acute promyelocytic leukemia cells.Therapeutic potential of interleukin-17 in inflammation and autoimmune diseases.Temporal cytokine expression and the target organ attributes unravel novel aspects of autoimmune arthritis.Control of autoimmune inflammation by celastrol, a natural triterpenoid.Celastrol Attenuates Multiple Sclerosis and Optic Neuritis in an Experimental Autoimmune Encephalomyelitis Model.Celastrol: A Spectrum of Treatment Opportunities in Chronic DiseasesCelastrol inhibits inflammatory stimuli-induced neutrophil extracellular trap formationEffect of celastrol on bone structure and mechanics in arthritic rats.Mediators of inflammation-induced bone damage in arthritis and their control by herbal productsInvolvement of the IL-23/IL-17 axis and the Th17/Treg balance in the pathogenesis and control of autoimmune arthritis.Suppression of Inflammation and Arthritis by Orally Administrated Cardiotoxin from Naja naja atra.Celastrol attenuates pain and cartilage damage via SDF-1/CXCR4 signalling pathway in osteoarthritis rats.Suppression of NF-κB p65 nuclear translocation and tumor necrosis factor-α by Pongamia pinnata seed extract in adjuvant-induced arthritis.The Calcium-Induced Regulation in the Molecular and Transcriptional Circuitry of Human Inflammatory Response and Autoimmunity.The effect of celastrol on the ocular hypertension-induced degeneration of retinal ganglion cells.Celastrol and Its Role in Controlling Chronic Diseases.Altered Th17/Treg balance and dysregulated IL-1β response influence susceptibility/resistance to experimental autoimmune arthritis.Tinospora cordifolia inhibits autoimmune arthritis by regulating key immune mediators of inflammation and bone damage.Chemopreventive activity of celastrol in drug-resistant human colon carcinoma cell cultures.
P2860
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P2860
Celastrus-derived celastrol suppresses autoimmune arthritis by modulating antigen-induced cellular and humoral effector responses
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
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name
Celastrus-derived celastrol su ...... and humoral effector responses
@ast
Celastrus-derived celastrol su ...... and humoral effector responses
@en
Celastrus-derived celastrol su ...... and humoral effector responses
@nl
type
label
Celastrus-derived celastrol su ...... and humoral effector responses
@ast
Celastrus-derived celastrol su ...... and humoral effector responses
@en
Celastrus-derived celastrol su ...... and humoral effector responses
@nl
prefLabel
Celastrus-derived celastrol su ...... and humoral effector responses
@ast
Celastrus-derived celastrol su ...... and humoral effector responses
@en
Celastrus-derived celastrol su ...... and humoral effector responses
@nl
P2093
P2860
P356
P1476
Celastrus-derived celastrol su ...... and humoral effector responses
@en
P2093
Kamal D Moudgil
Rajesh Rajaiah
Shivaprasad H Venkatesha
P2860
P304
15138-15146
P356
10.1074/JBC.M111.226365
P407
P577
2011-03-14T00:00:00Z