Distinct pathogenic processes between Fig4-deficient motor and sensory neurons.

Distinct pathogenic processes between Fig4-deficient motor and sensory neurons.

Item
http://www.wikidata.org/entity/Q34171101
Phosphatidylinositol 3,5-bisphosphate: low abundance, high significanceNeuronal expression of Fig4 is both necessary and sufficient to prevent spongiform neurodegeneration.Accumulation of misfolded SOD1 in dorsal root ganglion degenerating proprioceptive sensory neurons of transgenic mice with amyotrophic lateral sclerosisMouse models of PI(3,5)P2 deficiency with impaired lysosome function.Whole exome sequencing identifies three recessive FIG4 mutations in an apparently dominant pedigree with Charcot-Marie-Tooth disease.Loss of Fig4 in both Schwann cells and motor neurons contributes to CMT4J neuropathy.Reactivation of Lysosomal Ca2+ Efflux Rescues Abnormal Lysosomal Storage in FIG4-Deficient CellsPhosphoinositides and vesicular membrane trafficModulation of synaptic function by VAC14, a protein that regulates the phosphoinositides PI(3,5)P₂ and PI(5)PFig4 deficiency: a newly emerged lysosomal storage disorder?Phosphatidylinositol-3,5-bisphosphate: no longer the poor PIP2.FIG4 regulates lysosome membrane homeostasis independent of phosphatase function.A simple, step-by-step dissection protocol for the rapid isolation of mouse dorsal root ganglia.Autophagy as an Emerging Common Pathomechanism in Inherited Peripheral Neuropathies.Myelin abnormality in Charcot-Marie-Tooth type 4J recapitulates features of acquired demyelination.
P2860

Distinct pathogenic processes between Fig4-deficient motor and sensory neurons.

Item
http://www.wikidata.org/entity/Q34171101
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Distinct pathogenic processes between Fig4-deficient motor and sensory neurons.
@ast
Distinct pathogenic processes between Fig4-deficient motor and sensory neurons.
@en
Distinct pathogenic processes between Fig4-deficient motor and sensory neurons.
@nl
type
label
Distinct pathogenic processes between Fig4-deficient motor and sensory neurons.
@ast
Distinct pathogenic processes between Fig4-deficient motor and sensory neurons.
@en
Distinct pathogenic processes between Fig4-deficient motor and sensory neurons.
@nl
prefLabel
Distinct pathogenic processes between Fig4-deficient motor and sensory neurons.
@ast
Distinct pathogenic processes between Fig4-deficient motor and sensory neurons.
@en
Distinct pathogenic processes between Fig4-deficient motor and sensory neurons.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
Distinct pathogenic processes between Fig4-deficient motor and sensory neurons
@en
P2093
P2860
P304
P31
P356
10.1111/J.1460-9568.2011.07651.X
P407
P433
P478
P50
P577
P698