Onchocerciasis: the role of Wolbachia bacterial endosymbionts in parasite biology, disease pathogenesis, and treatment. - Test2 - elhamkhani - TriplyDB

Onchocerciasis: the role of Wolbachia bacterial endosymbionts in parasite biology, disease pathogenesis, and treatment.

Onchocerciasis: the role of Wolbachia bacterial endosymbionts in parasite biology, disease pathogenesis, and treatment.

http://www.wikidata.org/entity/Q34198127

about

A novel bacterial symbiont in the nematode Spirocerca lupi Doxycycline plus ivermectin versus ivermectin alone for treatment of patients with onchocerciasis Doxycycline plus ivermectin versus ivermectin alone for treating onchocerciasis Chronic filarial infection provides protection against bacterial sepsis by functionally reprogramming macrophages Research for new drugs for elimination of onchocerciasis in Africa WIPO Re:Search: Accelerating anthelmintic development through cross-sector partnerships Anti-Wolbachia drug discovery and development: safe macrofilaricides for onchocerciasis and lymphatic filariasis Immunoepidemiological profiling of onchocerciasis patients reveals associations with microfilaria loads and ivermectin intake on both individual and community levels A host as an ecosystem: Wolbachia coping with environmental constraints.Both asymmetric mitotic segregation and cell-to-cell invasion are required for stable germline transmission of Wolbachia in filarial nematodes.Significant heterogeneity in Wolbachia copy number within and between populations of Onchocerca volvulus Modelling the impact of ivermectin on River Blindness and its burden of morbidity and mortality in African Savannah: EpiOncho projections.Migratory phase of Litomosoides sigmodontis filarial infective larvae is associated with pathology and transient increase of S100A9 expressing neutrophils in the lung.Endosymbiotic bacteria associated with nematodes, ticks and amoebae.Comparative analysis of the secretome from a model filarial nematode (Litomosoides sigmodontis) reveals maximal diversity in gravid female parasites.Human and animal dirofilariasis: the emergence of a zoonotic mosaic.Wolbachia lipoproteins: abundance, localisation and serology of Wolbachia peptidoglycan associated lipoprotein and the Type IV Secretion System component, VirB6 from Brugia malayi and Aedes albopictus.Human filarial Wolbachia lipopeptide directly activates human neutrophils in vitro Hyperreactive onchocerciasis is characterized by a combination of Th17-Th2 immune responses and reduced regulatory T cells.Reductions in microfilaridermia by repeated ivermectin treatment are associated with lower Plasmodium-specific Th17 immune responses in Onchocerca volvulus-infected individuals.Retarded Onchocerca volvulus L1 to L3 larval development in the Simulium damnosum vector after anti-wolbachial treatment of the human host.Long term impact of large scale community-directed delivery of doxycycline for the treatment of onchocerciasis.Ophthalmic parasitosis: a review article.Validation of onchocerciasis biomarker N-acetyltyramine-O-glucuronide (NATOG).Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis.Onchocerciasis, an undiagnosed disease in Mozambique: identifying research opportunities.Host defense at the ocular surface Wolbachia endosymbionts induce neutrophil extracellular trap formation in human onchocerciasis.NOD2 dependent neutrophil recruitment is required for early protective immune responses against infectious Litomosoides sigmodontis L3 larvae.Important progress towards elimination of onchocerciasis in the West Region of Cameroon.Functional attributes of evolutionary conserved Arg45 of Wolbachia (Brugia malayi) translation initiation factor-1.Evaluation of Onchocerciasis Transmission in Tanzania: Preliminary Rapid Field Results in the Tukuyu Focus, 2015.Patency of Litomosoides sigmodontis infection depends on Toll-like receptor 4 whereas Toll-like receptor 2 signalling influences filarial-specific CD4(+) T-cell responses.A five-year-old child with a subcutaneous forehead nodule.Retinoid Expression in Onchocercal Skin Disease: Pilot Study.Onchodermatitis: Where Are We Now?

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Onchocerciasis: the role of Wolbachia bacterial endosymbionts in parasite biology, disease pathogenesis, and treatment.

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Onchocerciasis: the role of Wo ...... e pathogenesis, and treatment.

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Eric Pearlman

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Francesca Tamarozzi

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Katrin Gentil

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Feasibility of onchocerciasis elimination with ivermectin treatment in endemic foci in Africa: first evidence from studies in Mali and Senegal

Assessment of microfilarial loads in the skin of onchocerciasis patients after treatment with different regimens of doxycycline plus ivermectin

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

Brugia malayi excreted/secreted proteins at the host/parasite interface: stage- and gender-specific proteomic profiling

The heme biosynthetic pathway of the obligate Wolbachia endosymbiont of Brugia malayi as a potential anti-filarial drug target

Community-directed delivery of doxycycline for the treatment of onchocerciasis in areas of co-endemicity with loiasis in Cameroon

Macrofilaricidal activity after doxycycline only treatment of Onchocerca volvulus in an area of Loa loa co-endemicity: a randomized controlled trial.

Computational prediction of essential genes in an unculturable endosymbiotic bacterium, Wolbachia of Brugia malayi

River blindness: a success story under threat?

Wolbachia bacteria of filarial nematodes.

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10.1128/CMR.00057-10

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