Phase I/IIa study of intratumoral/intracerebral or intravenous/intracerebral administration of Parvovirus H-1 (ParvOryx) in patients with progressive primary or recurrent glioblastoma multiforme: ParvOryx01 protocol

Phase I/IIa study of intratumoral/intracerebral or intravenous/intracerebral administration of Parvovirus H-1 (ParvOryx) in patients with progressive primary or recurrent glioblastoma multiforme: ParvOryx01 protocol

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http://www.wikidata.org/entity/Q34205208

Q34205208

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Moving oncolytic viruses into the clinic: clinical-grade production, purification, and characterization of diverse oncolytic viruses The ex vivo purge of cancer cells using oncolytic viruses: recent advances and clinical implications Emerging role of Natural killer cells in oncolytic virotherapy Structural Characterization of H-1 Parvovirus: Comparison of Infectious Virions to Empty Capsids Oncolytic parvoviruses: from basic virology to clinical applications PKCη/Rdx-driven phosphorylation of PDK1: a novel mechanism promoting cancer cell survival and permissiveness for parvovirus-induced lysis Oncolytic virotherapy as emerging immunotherapeutic modality: potential of parvovirus h-1 Evolution of malignant glioma treatment: from chemotherapy to vaccines to viruses.TLR-9 contributes to the antiviral innate immune sensing of rodent parvoviruses MVMp and H-1PV by normal human immune cells.Vesicular transport of progeny parvovirus particles through ER and Golgi regulates maturation and cytolysis Intravenous administration of retroviral replicating vector, Toca 511, demonstrates therapeutic efficacy in orthotopic immune-competent mouse glioma model Induction of an embryonic mouse innate immune response following inoculation in utero with minute virus of mice.Phase I trial of Seneca Valley Virus (NTX-010) in children with relapsed/refractory solid tumors: a report of the Children's Oncology Group.Pathology, organ distribution, and immune response after single and repeated intravenous injection of rats with clinical-grade parvovirus H1 Bioavailability, biodistribution, and CNS toxicity of clinical-grade parvovirus H1 after intravenous and intracerebral injection in rats.Tumor Selectivity of Oncolytic Parvoviruses: From in vitro and Animal Models to Cancer Patients.Unlocking the promise of oncolytic virotherapy in glioma: combination with chemotherapy to enhance efficacy The Mammalian Cell Cycle Regulates Parvovirus Nuclear Capsid Assembly.Liposomal n-butylidenephthalide protects the drug from oxidation and enhances its antitumor effects in glioblastoma multiforme.Production, purification, crystallization and structure determination of H-1 Parvovirus.EXPLORING THE ANTITUMOR EFFECT OF VIRUS IN MALIGNANT GLIOMA Assessment of current virotherapeutic application schemes: "hit hard and early" versus "killing softly"?Pediatric and Adult High-Grade Glioma Stem Cell Culture Models Are Permissive to Lytic Infection with Parvovirus H-1.Trial watch: Oncolytic viruses for cancer therapy Intratumoral chemotherapy for lung cancer: re-challenge current targeted therapies.Synergistic combination of valproic acid and oncolytic parvovirus H-1PV as a potential therapy against cervical and pancreatic carcinomas The Methanol Extract of Angelica sinensis Induces Cell Apoptosis and Suppresses Tumor Growth in Human Malignant Brain Tumors Glioma virus therapies between bench and bedside.Clinical trials of viral therapy for malignant gliomas.Viral genes as oncolytic agents for cancer therapy.Profiling of Host Cell Response to Successive Canine Parvovirus Infection Based on Kinetic Proteomic Change Identification.Intratumoral gene therapy versus intravenous gene therapy for distant metastasis control with 2-diethylaminoethyl-dextran methyl methacrylate copolymer non-viral vector-p53.Role of NK cells in immunotherapy and virotherapy of solid tumors.Oncolytic viruses: a new class of immunotherapy drugs.Fighting Cancer with Mathematics and Viruses.Advancing Cancer Therapy with Present and Emerging Immuno-Oncology Approaches Mesenchymal stromal cells for the delivery of oncolytic viruses in gliomas.Virotherapy of digestive tumors with rodent parvovirus: overview and perspectives.Oncolytic Virotherapy for the Treatment of Malignant Glioma.Exosomes as Tools to Suppress Primary Brain Tumor.

P2860

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P2860

Phase I/IIa study of intratumoral/intracerebral or intravenous/intracerebral administration of Parvovirus H-1 (ParvOryx) in patients with progressive primary or recurrent glioblastoma multiforme: ParvOryx01 protocol

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description

2012 nî lūn-bûn

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2012 թուականի Մարտին հրատարակուած գիտական յօդուած

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2012 թվականի մարտին հրատարակված գիտական հոդված

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2012年論文

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Phase I/IIa study of intratumo ...... ultiforme: ParvOryx01 protocol

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Phase I/IIa study of intratumo ...... ministration of Parvovirus H-1

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Phase I/IIa study of intratumo ...... ultiforme: ParvOryx01 protocol

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Phase I/IIa study of intratumo ...... ultiforme: ParvOryx01 protocol

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Phase I/IIa study of intratumo ...... ultiforme: ParvOryx01 protocol

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P2093

Barbara Leuchs

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Bernard Huber

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Jacek Hajda

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Jean Rommelaere

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Joerg R Schlehofer

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Johannes Huesing

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Karsten Geletneky

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Magnus von Knebel Doeberitz

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Michael Dahm

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Ottheinz Krebs

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P2860

Temporal trends in incidence of primary brain tumors in the United States, 1985-1999

HSV1716 injection into the brain adjacent to tumour following surgical resection of high-grade glioma: safety data and long-term survival.

Recent advances in therapy for glioblastoma.

Phase III study of enzastaurin compared with lomustine in the treatment of recurrent intracranial glioblastoma.

Phase Ib trial of mutant herpes simplex virus G207 inoculated pre-and post-tumor resection for recurrent GBM

Regression of advanced rat and human gliomas by local or systemic treatment with oncolytic parvovirus H-1 in rat models.

Oncolytic viruses: clinical applications as vectors for the treatment of malignant gliomas.

Oncolytic potential of rodent parvoviruses for cancer therapy in humans: a brief review.

Antineoplastic activity of parvoviruses.

Oncolytic parvoviruses as cancer therapeutics.

P2888

1471-2407-12-99

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10.1186/1471-2407-12-99

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English

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2012-03-21T00:00:00Z

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221903257

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1031811534

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22436661

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3425127

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Phase I/IIa study of intratumoral/intracerebral or intravenous/intracerebral administration of Parvovirus H-1 (ParvOryx) in patients with progressive primary or recurrent glioblastoma multiforme: ParvOryx01 protocol

about

P2860

P2860

Phase I/IIa study of intratumoral/intracerebral or intravenous/intracerebral administration of Parvovirus H-1 (ParvOryx) in patients with progressive primary or recurrent glioblastoma multiforme: ParvOryx01 protocol

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