Targeted inhibition of BRAF kinase: opportunities and challenges for therapeutics in melanoma.
about
Rapid, Microwave-Assisted Organic Synthesis of Selective (V600E)BRAF Inhibitors for Preclinical Cancer Research.Overexpression of Mcl-1 confers resistance to BRAFV600E inhibitors alone and in combination with MEK1/2 inhibitors in melanoma.SOX10 ablation arrests cell cycle, induces senescence, and suppresses melanomagenesisPhenformin enhances the therapeutic benefit of BRAF(V600E) inhibition in melanoma.Phosphorylation of BRAF by AMPK impairs BRAF-KSR1 association and cell proliferation.Inducible Mouse Models for Cancer Drug Target Validation.NCCN Working Group report: designing clinical trials in the era of multiple biomarkers and targeted therapies.Non-BRAF targeted therapies for melanoma: protein kinase inhibitors in Phase II clinical trials.Simultaneous blocking of IL-6 and IL-8 is sufficient to fully inhibit CAF-induced human melanoma cell invasiveness.
P2860
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P2860
Targeted inhibition of BRAF kinase: opportunities and challenges for therapeutics in melanoma.
description
2012 nî lūn-bûn
@nan
2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2012年の論文
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2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Targeted inhibition of BRAF ki ...... for therapeutics in melanoma.
@ast
Targeted inhibition of BRAF ki ...... for therapeutics in melanoma.
@en
Targeted inhibition of BRAF ki ...... for therapeutics in melanoma.
@nl
type
label
Targeted inhibition of BRAF ki ...... for therapeutics in melanoma.
@ast
Targeted inhibition of BRAF ki ...... for therapeutics in melanoma.
@en
Targeted inhibition of BRAF ki ...... for therapeutics in melanoma.
@nl
prefLabel
Targeted inhibition of BRAF ki ...... for therapeutics in melanoma.
@ast
Targeted inhibition of BRAF ki ...... for therapeutics in melanoma.
@en
Targeted inhibition of BRAF ki ...... for therapeutics in melanoma.
@nl
P2860
P356
P1433
P1476
Targeted inhibition of BRAF ki ...... for therapeutics in melanoma.
@en
P2093
Rolando Pérez-Lorenzo
P2860
P356
10.1042/BSR20110068
P577
2012-02-01T00:00:00Z