Delivery of antibodies to the cytosol: debunking the myths.
about
Antibodies inside of a cell can change its outside: Can intrabodies provide a new therapeutic paradigm?Specific in vivo knockdown of protein function by intrabodiesAntibody targeting intracellular oncogenic Ras mutants exerts anti-tumour effects after systemic administration.A general strategy for generating intact, full-length IgG antibodies that penetrate into the cytosol of living cells.Functional knock down of VCAM1 in mice mediated by endoplasmatic reticulum retained intrabodiesSingle domain antibodies for the knockdown of cytosolic and nuclear proteins.In vitro and ex vivo strategies for intracellular delivery.Current progress in innovative engineered antibodies.Evaluating the Delivery of Proteins to the Cytosol of Mammalian Cells.Intracellular immunization against HIV infection with an intracellular antibody that mimics HIV integrase binding to the cellular LEDGF protein.Transduction Methods for Cytosolic Delivery of Proteins and Bioconjugates into Living Cells.Imaging of native transcription factors and histone phosphorylation at high resolution in live cells.Restoring functional neurofibromin by protein transduction.Neue Impulse für den Protein-Knock-down mit intrabodiesTargeted Intracellular Delivery of Antibodies: The State of the Art
P2860
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P2860
Delivery of antibodies to the cytosol: debunking the myths.
description
2014 nî lūn-bûn
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2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
@zh-hans
2014年学术文章
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2014年学术文章
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2014年學術文章
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name
Delivery of antibodies to the cytosol: debunking the myths.
@ast
Delivery of antibodies to the cytosol: debunking the myths.
@en
Delivery of antibodies to the cytosol: debunking the myths.
@nl
type
label
Delivery of antibodies to the cytosol: debunking the myths.
@ast
Delivery of antibodies to the cytosol: debunking the myths.
@en
Delivery of antibodies to the cytosol: debunking the myths.
@nl
prefLabel
Delivery of antibodies to the cytosol: debunking the myths.
@ast
Delivery of antibodies to the cytosol: debunking the myths.
@en
Delivery of antibodies to the cytosol: debunking the myths.
@nl
P2093
P2860
P50
P356
P1476
Delivery of antibodies to the cytosol: debunking the myths.
@en
P2093
André Frenzel
Congcong Zhang
Thomas Schirrmann
P2860
P304
P356
10.4161/MABS.29268
P577
2014-05-21T00:00:00Z