A weak signal for strong responses: interferon-alpha/beta revisited. - Test2 - elhamkhani - TriplyDB

A weak signal for strong responses: interferon-alpha/beta revisited.

A weak signal for strong responses: interferon-alpha/beta revisited.

http://www.wikidata.org/entity/Q34238056

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Harnessing Mechanistic Knowledge on Beneficial Versus Deleterious IFN-I Effects to Design Innovative Immunotherapies Targeting Cytokine Activity to Specific Cell Types Overview of the biology of type I interferons The role of genetic variation near interferon-kappa in systemic lupus erythematosus IFI16 protein mediates the anti-inflammatory actions of the type-I interferons through suppression of activation of caspase-1 by inflammasomes Neutrophils responsive to endogenous IFN-beta regulate tumor angiogenesis and growth in a mouse tumor model The zinc finger antiviral protein acts synergistically with an interferon-induced factor for maximal activity against alphaviruses Therapeutic Targets for Neurodevelopmental Disorders Emerging from Animal Models with Perinatal Immune Activation RPA and Rad51 constitute a cell intrinsic mechanism to protect the cytosol from self DNA Leukocyte-derived IFN-α/β and epithelial IFN-λ constitute a compartmentalized mucosal defense system that restricts enteric virus infections Antiviral effect and virus-host interactions in response to alpha interferon, gamma interferon, poly(i)-poly(c), tumor necrosis factor alpha, and ribavirin in hepatitis C virus subgenomic replicons.Fast type I interferon response protects astrocytes from flavivirus infection and virus-induced cytopathic effects The Importance of Physiologically Relevant Cell Lines for Studying Virus-Host Interactions SOCS1 Mimetics and Antagonists: A Complementary Approach to Positive and Negative Regulation of Immune Function A BRISC-SHMT complex deubiquitinates IFNAR1 and regulates interferon responses Cockayne syndrome group B protein (CSB) plays a general role in chromatin maintenance and remodeling Regulation of the type I IFN induction: a current view Type I interferon: friend or foe?High serum IFN-alpha activity is a heritable risk factor for systemic lupus erythematosus A completely foreign receptor can mediate an interferon-gamma-like response.Twist mediates suppression of inflammation by type I IFNs and Axl Interferon-γ Inhibits Ebola Virus Infection Differential expression of tapasin and immunoproteasome subunits in adenovirus type 5- versus type 12-transformed cells Contraction of the type I IFN locus and unusual constitutive expression of IFN-α in bats Cytokine Activation by Antibody Fragments Targeted to Cytokine-Receptor Signaling Complexes.Importance of the interferon-alpha system in murine large intestine indicated by microarray analysis of commensal bacteria-induced immunological changes.Type I interferon signaling genes in recurrent major depression: increased expression detected by whole-blood RNA sequencing Novel pegylated interferon-β as strong suppressor of the malignant ascites in a peritoneal metastasis model of human cancer.Latent membrane protein 1 regulates STAT1 through NF-kappaB-dependent interferon secretion in Epstein-Barr virus-immortalized B cells.TLR4 ligands induce IFN-alpha production by mouse conventional dendritic cells and human monocytes after IFN-beta priming NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway Basal and reovirus-induced beta interferon (IFN-beta) and IFN-beta-stimulated gene expression are cell type specific in the cardiac protective response.Production of IFN-β during Listeria monocytogenes infection is restricted to monocyte/macrophage lineage Inhibition of IFN-gamma-dependent antiviral airway epithelial defense by cigarette smoke.Interferons, signal transduction pathways, and the central nervous system.Interferons and their stimulated genes in the tumor microenvironment Defining emerging roles for NF-κB in antivirus responses: revisiting the interferon-β enhanceosome paradigm.High-throughput identification of loss-of-function mutations for anti-interferon activity in the influenza A virus NS segment.Microarray analysis on germfree mice elucidates the primary target of a traditional Japanese medicine juzentaihoto: acceleration of IFN-α response via affecting the ISGF3-IRF7 signaling cascade Differential antiviral response of endothelial cells after infection with pathogenic and nonpathogenic hantaviruses Critical role of constitutive type I interferon response in bronchial epithelial cell to influenza infection.

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A weak signal for strong responses: interferon-alpha/beta revisited.

http://www.wikidata.org/entity/Q34238056

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2001 nî lūn-bûn

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2001 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2001 թվականի մայիսին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年论文

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A weak signal for strong responses: interferon-alpha/beta revisited.

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A weak signal for strong responses: interferon-alpha/beta revisited.

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A weak signal for strong responses: interferon-alpha/beta revisited.

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A weak signal for strong responses: interferon-alpha/beta revisited.

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A weak signal for strong responses: interferon-alpha/beta revisited.

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A weak signal for strong responses: interferon-alpha/beta revisited.

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A weak signal for strong responses: interferon-alpha/beta revisited.

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A weak signal for strong responses: interferon-alpha/beta revisited.

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A weak signal for strong responses: interferon-alpha/beta revisited.

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Nature Reviews Molecular Cell Biology

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A weak signal for strong responses: interferon-alpha/beta revisited.

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Takaoka A

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Taniguchi T

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P2860

Functional role of type I and type II interferons in antiviral defense

Genetic transfer of a functional human interferon alpha receptor into mouse cells: cloning and expression of its cDNA

Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

The human interferon alpha/beta receptor: characterization and molecular cloning

Requirement of ErbB2 for signalling by interleukin-6 in prostate carcinoma cells

Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7

PRDI-BF1/Blimp-1 repression is mediated by corepressors of the Groucho family of proteins

Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling

Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

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378-386

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10.1038/35073080

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