Mutation of a U2 snRNA gene causes global disruption of alternative splicing and neurodegeneration
about
Identification of a PRPF4 loss-of-function variant that abrogates U4/U6.U5 tri-snRNP integration and is associated with retinitis pigmentosaRegulation of protein homeostasis in neurodegenerative diseases: the role of coding and non-coding genesThe neurogenetics of alternative splicingChondrolectin affects cell survival and neuronal outgrowth in in vitro and in vivo models of spinal muscular atrophyBiallelic mutations in the 3' exonuclease TOE1 cause pontocerebellar hypoplasia and uncover a role in snRNA processing.Spliceosomal protein eftud2 mutation leads to p53-dependent apoptosis in zebrafish neural progenitors.Human mutations in integrator complex subunits link transcriptome integrity to brain development.Biochemical defects in minor spliceosome function in the developmental disorder MOPD I.sCLIP-an integrated platform to study RNA-protein interactomes in biomedical research: identification of CSTF2tau in alternative processing of small nuclear RNAs.Direct visualization of the highly polymorphic RNU2 locus in proximity to the BRCA1 gene.Genome-wide discovery of human splicing branchpointsDefective structural RNA processing in relapsing-remitting multiple sclerosisRegulation of toll-like receptor signaling by the SF3a mRNA splicing complex.Dark matter RNA: an intelligent scaffold for the dynamic regulation of the nuclear information landscapeReplication-dependent histone genes are actively transcribed in differentiating and aging retinal neurons.Differentially expressed, variant U1 snRNAs regulate gene expression in human cellsTissue plasminogen activator regulates Purkinje neuron development and survival.Post-transcriptional regulation of myotube elongation and myogenesis by Hoi Polloi.Variant U1 snRNAs are implicated in human pluripotent stem cell maintenance and neuromuscular disease.SMN deficiency in severe models of spinal muscular atrophy causes widespread intron retention and DNA damageMinor splicing pathway is not minor any more: implications for the pathogenesis of motor neuron diseases.Gem depletion: amyotrophic lateral sclerosis and spinal muscular atrophy crossover.Insights into the U1 small nuclear ribonucleoprotein complex superfamily.My road to alternative splicing control: from simple paths to loops and interconnections.Non-coding RNAs and disease: the classical ncRNAs make a comeback.Role of Ser7 phosphorylation of the CTD during transcription of snRNA genes.Developmental analysis of spliceosomal snRNA isoform expression.The splicing co-factor Barricade/Tat-SF1 is required for cell cycle and lineage progression in Drosophila neural stem cells.Mutation in noncoding RNA RNU12 causes early onset cerebellar ataxia.Proteomic Dissection of Nanotopography-Sensitive Mechanotransductive Signaling Hubs that Foster Neuronal Differentiation in PC12 Cells.Variant snRNPs: New players within the spliceosome system.PARIS: Psoralen Analysis of RNA Interactions and Structures with High Throughput and Resolution.U1 snRNP Alteration and Neuronal Cell Cycle Reentry in Alzheimer Disease.Functional Interplay between Small Non-Coding RNAs and RNA Modification in the Brain.
P2860
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P2860
Mutation of a U2 snRNA gene causes global disruption of alternative splicing and neurodegeneration
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Mutation of a U2 snRNA gene ca ...... splicing and neurodegeneration
@ast
Mutation of a U2 snRNA gene ca ...... splicing and neurodegeneration
@en
Mutation of a U2 snRNA gene ca ...... splicing and neurodegeneration
@nl
type
label
Mutation of a U2 snRNA gene ca ...... splicing and neurodegeneration
@ast
Mutation of a U2 snRNA gene ca ...... splicing and neurodegeneration
@en
Mutation of a U2 snRNA gene ca ...... splicing and neurodegeneration
@nl
prefLabel
Mutation of a U2 snRNA gene ca ...... splicing and neurodegeneration
@ast
Mutation of a U2 snRNA gene ca ...... splicing and neurodegeneration
@en
Mutation of a U2 snRNA gene ca ...... splicing and neurodegeneration
@nl
P2860
P1433
P1476
Mutation of a U2 snRNA gene ca ...... splicing and neurodegeneration
@en
P2093
Susan L Ackerman
Yichang Jia
P2860
P304
P356
10.1016/J.CELL.2011.11.057
P407
P50
P577
2012-01-01T00:00:00Z