Respiratory complex I is essential to induce a Warburg profile in mitochondria-defective tumor cells.
about
Energy metabolism in neuroblastoma and Wilms tumorDecoding Warburg's hypothesis: tumor-related mutations in the mitochondrial respiratory chainRedox control of glutamine utilization in cancerThe mitochondrial permeability transition pore and cancer: molecular mechanisms involved in cell deathDefects in mitochondrial metabolism and cancerStable nuclear expression of ATP8 and ATP6 genes rescues a mtDNA Complex V null mutantNuclear expression of mitochondrial ND4 leads to the protein assembling in complex I and prevents optic atrophy and visual loss.A Synthetic Lethal Interaction between Glutathione Synthesis and Mitochondrial Reactive Oxygen Species Provides a Tumor-Specific Vulnerability Dependent on STAT3.Enhanced tumorigenicity by mitochondrial DNA mild mutationsAn innovative strategy to clone positive modifier genes of defects caused by mtDNA mutations: MRPS18C as suppressor gene of m.3946G>A mutation in MT-ND1 gene.Targeting metabolic flexibility by simultaneously inhibiting respiratory complex I and lactate generation retards melanoma progression.Nuclear receptors and the Warburg effect in cancer.The opposite prognostic effect of NDUFS1 and NDUFS8 in lung cancer reflects the oncojanus role of mitochondrial complex IGene Therapy for Leber Hereditary Optic Neuropathy: Initial Results.Spotlight on the relevance of mtDNA in cancer.Analysis of the mitochondrial proteome of cybrid cells harbouring a truncative mitochondrial DNA mutation in respiratory complex I.Different mtDNA mutations modify tumor progression in dependence of the degree of respiratory complex I impairment.The α-ketoglutarate dehydrogenase complex in cancer metabolic plasticity.The Mitochondrial Complex(I)ty of Cancer.A comprehensive characterization of rare mitochondrial DNA variants in neuroblastoma.The ketogenic diet is not feasible as a therapy in a CD-1 nu/nu mouse model of renal cell carcinoma with features of Stauffer's syndrome.Metformin directly acts on mitochondria to alter cellular bioenergetics.Renal oncocytoma characterized by the defective complex I of the respiratory chain boosts the synthesis of the ROS scavenger glutathione.Non-Canonical Mechanisms Regulating Hypoxia-Inducible Factor 1 Alpha in Cancer.Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer.Cell death-based treatment of neuroblastoma.Unravelling the Effects of the Mutation m.3571insC/MT-ND1 on Respiratory Complexes Structural Organization.Metabolic Reprogramming in Thyroid Carcinoma.The Oncojanus Paradigm of Respiratory Complex I.
P2860
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P2860
Respiratory complex I is essential to induce a Warburg profile in mitochondria-defective tumor cells.
description
2013 nî lūn-bûn
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2013 թուականի Մարտին հրատարակուած գիտական յօդուած
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2013 թվականի մարտին հրատարակված գիտական հոդված
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2013年の論文
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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name
Respiratory complex I is essen ...... hondria-defective tumor cells.
@ast
Respiratory complex I is essen ...... hondria-defective tumor cells.
@en
Respiratory complex I is essen ...... hondria-defective tumor cells.
@nl
type
label
Respiratory complex I is essen ...... hondria-defective tumor cells.
@ast
Respiratory complex I is essen ...... hondria-defective tumor cells.
@en
Respiratory complex I is essen ...... hondria-defective tumor cells.
@nl
prefLabel
Respiratory complex I is essen ...... hondria-defective tumor cells.
@ast
Respiratory complex I is essen ...... hondria-defective tumor cells.
@en
Respiratory complex I is essen ...... hondria-defective tumor cells.
@nl
P2093
P2860
P50
P356
P1433
P1476
Respiratory complex I is essen ...... hondria-defective tumor cells.
@en
P2093
Anna Ghelli
Anna Maria Porcelli
Apollonia Tullo
Carla De Giovanni
Caterina Manzari
Christian Bergamini
Christine M Betts
Claudia Calabrese
Claudio Ceccarelli
Giordano Nicoletti
P2860
P2888
P356
10.1186/2049-3002-1-11
P50
P577
2013-03-18T00:00:00Z
P5875
P6179
1016655751