β-Secretase-1 elevation in aged monkey and Alzheimer's disease human cerebral cortex occurs around the vasculature in partnership with multisystem axon terminal pathogenesis and β-amyloid accumulation.
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γ-secretase binding sites in aged and Alzheimer's disease human cerebrum: the choroid plexus as a putative origin of CSF AβSortilin Fragments Deposit at Senile Plaques in Human CerebrumCerebral amyloid β(42) deposits and microvascular pathology in ageing baboons.Chronic temporal lobe epilepsy is associated with enhanced Alzheimer-like neuropathology in 3×Tg-AD miceInverse correlation between Alzheimer's disease and cancer: implication for a strong impact of regenerative propensity on neurodegeneration?BACE1 elevation is involved in amyloid plaque development in the triple transgenic model of Alzheimer's disease: differential Aβ antibody labeling of early-onset axon terminal pathology.Non-neuronal and neuronal BACE1 elevation in association with angiopathic and leptomeningeal β-amyloid deposition in the human brain.Experimental microembolism induces localized neuritic pathology in guinea pig cerebrum.Diosgenin is an exogenous activator of 1,25D₃-MARRS/Pdia3/ERp57 and improves Alzheimer's disease pathologies in 5XFAD miceBACE1 elevation is associated with aberrant limbic axonal sprouting in epileptic CD1 mice.Amyloid plaque pathogenesis in 5XFAD mouse spinal cord: retrograde transneuronal modulation after peripheral nerve injuryDistinct patterns of APP processing in the CNS in autosomal-dominant and sporadic Alzheimer diseaseCan BACE1 inhibition mitigate early axonal pathology in neurological diseases?Regulation of α-secretase ADAM10 expression and activity.The physiology of the β-amyloid precursor protein intracellular domain AICD.The Alzheimer's β-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques.Can brain impermeable BACE1 inhibitors serve as anti-CAA medicine?Kamikihi-to (KKT) rescues axonal and synaptic degeneration associated with memory impairment in a mouse model of Alzheimer's disease, 5XFAD.BACE1 elevation engendered by GGA3 deletion increases β-amyloid pathology in association with APP elevation and decreased CHL1 processing in 5XFAD mice.Does the Genetic Feature of the Chinese Tree Shrew (Tupaia belangeri chinensis) Support Its Potential as a Viable Model for Alzheimer's Disease Research?Amyloid generation and dysfunctional immunoproteasome activation with disease progression in animal model of familial Alzheimer's disease.Extracellular matrix protein expression is brain region dependent.Lack of human-like extracellular sortilin neuropathology in transgenic Alzheimer's disease model mice and macaques.
P2860
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P2860
β-Secretase-1 elevation in aged monkey and Alzheimer's disease human cerebral cortex occurs around the vasculature in partnership with multisystem axon terminal pathogenesis and β-amyloid accumulation.
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
β-Secretase-1 elevation in age ...... is and β-amyloid accumulation.
@ast
β-Secretase-1 elevation in age ...... is and β-amyloid accumulation.
@en
β-Secretase-1 elevation in age ...... is and β-amyloid accumulation.
@nl
type
label
β-Secretase-1 elevation in age ...... is and β-amyloid accumulation.
@ast
β-Secretase-1 elevation in age ...... is and β-amyloid accumulation.
@en
β-Secretase-1 elevation in age ...... is and β-amyloid accumulation.
@nl
prefLabel
β-Secretase-1 elevation in age ...... is and β-amyloid accumulation.
@ast
β-Secretase-1 elevation in age ...... is and β-amyloid accumulation.
@en
β-Secretase-1 elevation in age ...... is and β-amyloid accumulation.
@nl
P2093
P2860
P1476
β-Secretase-1 elevation in age ...... is and β-amyloid accumulation.
@en
P2093
Huaibin Cai
Jia-Chun Feng
Peter R Patrylo
Richard W Clough
Robert G Struble
Xiao-Xin Yan
Xue-Gang Luo
Xue-Mei Zhang
P2860
P304
P356
10.1111/J.1460-9568.2010.07376.X
P407
P577
2010-08-18T00:00:00Z