SOX2 gene regulates the transcriptional network of oncogenes and affects tumorigenesis of human lung cancer cells.
about
Induction of stem-like cells with malignant properties by chronic exposure of human lung epithelial cells to single-walled carbon nanotubesThe role of SOX2 in small cell lung cancer, lung adenocarcinoma and squamous cell carcinoma of the lungProgression and metastasis of lung cancerTargeted Cancer Therapy: Vital Oncogenes and a New Molecular Genetic Paradigm for Cancer Initiation Progression and TreatmentConcomitant targeting of multiple key transcription factors effectively disrupts cancer stem cells enriched in side population of human pancreatic cancer cellsSoluble extract from Moringa oleifera leaves with a new anticancer activityHigh expression of SOX2 is associated with poor prognosis in patients with salivary gland adenoid cystic carcinomaSOX2 expression is an early event in a murine model of EGFR mutant lung cancer and promotes proliferation of a subset of EGFR mutant lung adenocarcinoma cell lines.Next-generation sequencing reveals frequent consistent genomic alterations in small cell undifferentiated lung cancer.Generation and characterisation of cisplatin-resistant non-small cell lung cancer cell lines displaying a stem-like signature.The TBC1D15 oncoprotein controls stem cell self-renewal through destabilization of the Numb-p53 complexPrognostic significance of PIK3CA and SOX2 in Asian patients with lung squamous cell carcinoma.Sox2 suppresses the invasiveness of breast cancer cells via a mechanism that is dependent on Twist1 and the status of Sox2 transcription activity.Acetylation-dependent regulation of essential iPS-inducing factors: a regulatory crossroad for pluripotency and tumorigenesisM2 macrophages activate WNT signaling pathway in epithelial cells: relevance in ulcerative colitisOncogenesis and induced pluripotency - commonalities of signalling pathwaysAutologous anti-SOX2 antibody responses reflect intensity but not frequency of antigen expression in small cell lung cancer.Evaluation of stem-like side population cells in a recurrent nasopharyngeal carcinoma cell line.Dedifferentiation of patient-derived glioblastoma multiforme cell lines results in a cancer stem cell-like state with mitogen-independent growthFBXO31 promotes cell proliferation, metastasis and invasion in lung cancer.Mutations in TP53 increase the risk of SOX2 copy number alterations and silencing of TP53 reduces SOX2 expression in non-small cell lung cancer.An Integrated Molecular Analysis of Lung Adenocarcinomas Identifies Potential Therapeutic Targets among TTF1-Negative Tumors, Including DNA Repair Proteins and Nrf2.The converging roles of BRD4 and gene transcription in pluripotency and oncogenesisRoles of sex-determining region Y-box 2 in cell pluripotency and tumor-related signaling pathways.The role of Sox genes in lung morphogenesis and cancer.SOX2 suppresses CDKN1A to sustain growth of lung squamous cell carcinoma.Arsenic trioxide inhibits cancer stem-like cells via down-regulation of Gli1 in lung cancer.Stemness and inducing differentiation of small cell lung cancer NCI-H446 cells.Elevated expression of SOX2 and FGFR1 in correlation with poor prognosis in patients with small cell lung cancer.Association of SOX2 and Nestin DNA amplification and protein expression with clinical features and overall survival in non-small cell lung cancer: A systematic review and meta-analysis.The multiple roles for Sox2 in stem cell maintenance and tumorigenesis.Sox2 inhibits Wnt-β-catenin signaling and metastatic potency of cisplatin-resistant lung adenocarcinoma cells.A plethora of human pluripotent stem cells.Induced Pluripotent Stem Cells and Disorders of the Nervous System: Progress, Problems, and Prospects.ZNF281/ZBP-99: a new player in epithelial-mesenchymal transition, stemness, and cancer.SOX2 and cancer: current research and its implications in the clinicIntracellular signals of lung cancer cells as possible therapeutic targets.The mechanisms for lung cancer risk of PM2.5 : Induction of epithelial-mesenchymal transition and cancer stem cell properties in human non-small cell lung cancer cells.Pluripotency transcription factors in lung cancer-a review.Current status of treating neurodegenerative disease with induced pluripotent stem cells.
P2860
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P2860
SOX2 gene regulates the transcriptional network of oncogenes and affects tumorigenesis of human lung cancer cells.
description
2012 nî lūn-bûn
@nan
2012 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
SOX2 gene regulates the transc ...... is of human lung cancer cells.
@ast
SOX2 gene regulates the transc ...... is of human lung cancer cells.
@en
SOX2 gene regulates the transc ...... is of human lung cancer cells.
@nl
type
label
SOX2 gene regulates the transc ...... is of human lung cancer cells.
@ast
SOX2 gene regulates the transc ...... is of human lung cancer cells.
@en
SOX2 gene regulates the transc ...... is of human lung cancer cells.
@nl
prefLabel
SOX2 gene regulates the transc ...... is of human lung cancer cells.
@ast
SOX2 gene regulates the transc ...... is of human lung cancer cells.
@en
SOX2 gene regulates the transc ...... is of human lung cancer cells.
@nl
P2093
P2860
P1433
P1476
SOX2 gene regulates the transc ...... is of human lung cancer cells.
@en
P2093
Ralph A Reisfeld
Rong Xiang
Wenjun Mou
Yanan Chen
Yanhua Liu
P2860
P304
P356
10.1371/JOURNAL.PONE.0036326
P407
P577
2012-05-15T00:00:00Z