Total synthesis of [Ψ[C(═NH)NH]Tpg(4)]vancomycin and its (4-chlorobiphenyl)methyl derivative: impact of peripheral modifications on vancomycin analogues redesigned for dual D-Ala-D-Ala and D-Ala-D-Lac binding.

Total synthesis of [Ψ[C(═NH)NH]Tpg(4)]vancomycin and its (4-chlorobiphenyl)methyl derivative: impact of peripheral modifications on vancomycin analogues redesigned for dual D-Ala-D-Ala and D-Ala-D-Lac binding.

Item
http://www.wikidata.org/entity/Q34282738
Endless Resistance. Endless Antibiotics?Structure diversification of vancomycin through peptide-catalyzed, site-selective lipidation: a catalysis-based approach to combat glycopeptide-resistant pathogens.Total syntheses and initial evaluation of [Ψ[C(═S)NH]Tpg⁴]vancomycin, [Ψ[C(═NH)NH]Tpg⁴]vancomycin, [Ψ[CH₂NH]Tpg⁴]vancomycin, and their (4-chlorobiphenyl)methyl derivatives: synergistic binding pocket and peripheral modifications for the glycopeptideIn Vitro Reconstitution of OxyA Enzymatic Activity Clarifies Late Steps in Vancomycin Biosynthesis.Rapid access to glycopeptide antibiotic precursor peptides coupled with cytochrome P450-mediated catalysis: towards a biomimetic synthesis of glycopeptide antibiotics.Total Syntheses of Vancomycin-Related Glycopeptide Antibiotics and Key Analogues.Applications of Nonenzymatic Catalysts to the Alteration of Natural Products.Natural product analogues: towards a blueprint for analogue-focused synthesis.Antibiotic That Inhibits the ATPase Activity of an ATP-Binding Cassette Transporter by Binding to a Remote Extracellular Site.Peripheral modifications of [Ψ[CH2NH]Tpg4]vancomycin with added synergistic mechanisms of action provide durable and potent antibiotics.Reengineering Antibiotics to Combat Bacterial Resistance: Click Chemistry [1,2,3]-Triazole Vancomycin Dimers with Potent Activity against MRSA and VRE.The Difference a Single Atom Can Make: Synthesis and Design at the Chemistry-Biology Interface.Developments in Glycopeptide Antibiotics.Natural Products as Platforms To Overcome Antibiotic Resistance.Novel Modifications of Glycopeptide Antibiotics via Total Synthesis.The race for antimicrobials in the multidrug resistance era.
P2860

Total synthesis of [Ψ[C(═NH)NH]Tpg(4)]vancomycin and its (4-chlorobiphenyl)methyl derivative: impact of peripheral modifications on vancomycin analogues redesigned for dual D-Ala-D-Ala and D-Ala-D-Lac binding.

Item
http://www.wikidata.org/entity/Q34282738
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Total synthesis of [Ψ[C
@nl
Total synthesis of [Ψ[C(═NH)NH ...... D-Ala and D-Ala-D-Lac binding.
@ast
Total synthesis of [Ψ[C(═NH)NH ...... D-Ala and D-Ala-D-Lac binding.
@en
type
label
Total synthesis of [Ψ[C
@nl
Total synthesis of [Ψ[C(═NH)NH ...... D-Ala and D-Ala-D-Lac binding.
@ast
Total synthesis of [Ψ[C(═NH)NH ...... D-Ala and D-Ala-D-Lac binding.
@en
prefLabel
Total synthesis of [Ψ[C
@nl
Total synthesis of [Ψ[C(═NH)NH ...... D-Ala and D-Ala-D-Lac binding.
@ast
Total synthesis of [Ψ[C(═NH)NH ...... D-Ala and D-Ala-D-Lac binding.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Total synthesis of [Ψ[C(═NH)NH ...... D-Ala and D-Ala-D-Lac binding.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932