A Sod2 null mutation confers severely reduced adult life span in Drosophila
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Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegansIs the oxidative stress theory of aging dead?The in vivo gene expression signature of oxidative stressOxidative stress is not a major contributor to somatic mitochondrial DNA mutationsSuperoxide dismutase 2 knockdown leads to defects in locomotor activity, sensitivity to paraquat, and increased cuticle pigmentation in Tribolium castaneum.Mitochondrial ROS and the Effectors of the Intrinsic Apoptotic Pathway in Aging Cells: The Discerning Killers!Multiple measures of functionality exhibit progressive decline in a parallel, stochastic fashion in Drosophila Sod2 null mutantsMechanism of silver nanoparticles action on insect pigmentation reveals intervention of copper homeostasisGenetically encoded redox sensor identifies the role of ROS in degenerative and mitochondrial disease pathogenesisMetal uptake by manganese superoxide dismutase.Update on the oxidative stress theory of aging: does oxidative stress play a role in aging or healthy aging?Mitochondrial manganese superoxide dismutase mRNA expression in human chorioamniotic membranes and its association with labor, inflammation, and infection.Sod2 haploinsufficiency does not accelerate aging of telomere dysfunctional miceAging: Dial M for MitochondriaCancer stem cell theory and the warburg effect, two sides of the same coin?A model of oxidative stress management: moderation of carbohydrate metabolizing enzymes in SOD1-null Drosophila melanogaster.Manganese superoxide dismutase: beyond life and deathDrosophila clueless is highly expressed in larval neuroblasts, affects mitochondrial localization and suppresses mitochondrial oxidative damage.SOD2, the principal scavenger of mitochondrial superoxide, is dispensable for embryogenesis and imaginal tissue development but essential for adult survivalCloning and expression analysis of Drosophila extracellular Cu Zn superoxide dismutaseNot all smokers die young: a model for hidden heterogeneity within the human populationA muscle-specific p38 MAPK/Mef2/MnSOD pathway regulates stress, motor function, and life span in Drosophila.Manganese superoxide dismutase: guardian of the powerhouse.Superoxide dismutase is dispensable for normal animal lifespanBasal brain oxidative and nitrative stress levels are finely regulated by the interplay between superoxide dismutase 2 and p53Differential transcriptional control of the superoxide dismutase-2 kappaB element in neurons and astrocytesA novel Drosophila SOD2 mutant demonstrates a role for mitochondrial ROS in neurodevelopment and diseaseTarget of rapamycin activation predicts lifespan in fruit flies.The essential requirement of an animal heme peroxidase protein during the wing maturation process in Drosophila.A Measurable increase in oxidative damage due to reduction in superoxide detoxification fails to shorten the life span of long-lived mitochondrial mutants of Caenorhabditis elegansMitochondrial Efficiency-Dependent Viability of Saccharomyces cerevisiae Mutants Carrying Individual Electron Transport Chain Component DeletionsActivation of superoxide dismutases: putting the metal to the pedal.The role of mitochondria in agingThe PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivoThe role of mitochondrial DNA mutations and free radicals in disease and ageingReduced SOD2 expression is associated with mortality of hepatocellular carcinoma patients in a mutant p53-dependent manner.Reduced mitochondrial SOD displays mortality characteristics reminiscent of natural agingExtension of lifespan and protection against oxidative stress by an antioxidant herb mixture complex (KPG-7) in Caenorhabditis elegans.The Mn-superoxide dismutase single nucleotide polymorphism rs4880 and the glutathione peroxidase 1 single nucleotide polymorphism rs1050450 are associated with aging and longevity in the oldest old.Sod2 knockdown in the musculature has whole-organism consequences in Drosophila.
P2860
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P2860
A Sod2 null mutation confers severely reduced adult life span in Drosophila
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2003 nî lūn-bûn
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2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2003年の論文
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2003年論文
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2003年論文
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2003年論文
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2003年論文
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2003年論文
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2003年论文
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A Sod2 null mutation confers severely reduced adult life span in Drosophila
@ast
A Sod2 null mutation confers severely reduced adult life span in Drosophila
@en
A Sod2 null mutation confers severely reduced adult life span in Drosophila
@nl
type
label
A Sod2 null mutation confers severely reduced adult life span in Drosophila
@ast
A Sod2 null mutation confers severely reduced adult life span in Drosophila
@en
A Sod2 null mutation confers severely reduced adult life span in Drosophila
@nl
prefLabel
A Sod2 null mutation confers severely reduced adult life span in Drosophila
@ast
A Sod2 null mutation confers severely reduced adult life span in Drosophila
@en
A Sod2 null mutation confers severely reduced adult life span in Drosophila
@nl
P2093
P2860
P1433
P1476
A Sod2 null mutation confers severely reduced adult life span in Drosophila
@en
P2093
Amy Belton
Anirban Paul
Atanu Duttaroy
Mukta Kundu
P2860
P304
P407
P577
2003-12-01T00:00:00Z