The centrosomal protein Lats2 is a phosphorylation target of Aurora-A kinase.
about
Merlin/NF2 loss-driven tumorigenesis linked to CRL4(DCAF1)-mediated inhibition of the hippo pathway kinases Lats1 and 2 in the nucleusLATS2-Ajuba complex regulates gamma-tubulin recruitment to centrosomes and spindle organization during mitosisPhosphorylation and stabilization of HURP by Aurora-A: implication of HURP as a transforming target of Aurora-AComponents of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunctionProtein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactionsA positive feedback loop between the p53 and Lats2 tumor suppressors prevents tetraploidizationMechanisms of Hippo pathway regulationThe Non-Canonical Role of Aurora-A in DNA ReplicationA Cell Biologist's Field Guide to Aurora Kinase InhibitorsSelective Aurora Kinase Inhibitors Identified Using a Taxol-Induced Checkpoint Sensitivity ScreenMolecular mechanism of Aurora A kinase autophosphorylation and its allosteric activation by TPX2The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling.Tumor suppressor NF2/Merlin is a microtubule stabilizer.KIBRA: In the brain and beyondLATS2 is de-methylated and overexpressed in nasopharyngeal carcinoma and predicts poor prognosis.Aurora kinase A is not involved in CPEB1 phosphorylation and cyclin B1 mRNA polyadenylation during meiotic maturation of porcine oocytesA novel cell-based, high-content assay for phosphorylation of Lats2 by Aurora A.The aurora kinases in cell cycle and leukemiaThe Lats2 tumor suppressor augments p53-mediated apoptosis by promoting the nuclear proapoptotic function of ASPP1Aurora A kinase modulates actin cytoskeleton through phosphorylation of Cofilin: Implication in the mitotic process.NDR kinases regulate essential cell processes from yeast to humans.Isolation and characterization of the TIGA genes, whose transcripts are induced by growth arrestp53: guardian of ploidyKIBRA protein phosphorylation is regulated by mitotic kinase aurora and protein phosphatase 1.Aberrant large tumor suppressor 2 (LATS2) gene expression correlates with EGFR mutation and survival in lung adenocarcinomas.A functional cooperativity between Aurora A kinase and LIM kinase1: implication in the mitotic processAIBp regulates mitotic entry and mitotic spindle assembly by controlling activation of both Aurora-A and Plk1.Lats1 suppresses centrosome overduplication by modulating the stability of Cdc25B.KIBRA regulates aurora kinase activity and is required for precise chromosome alignment during mitosis.Warts phosphorylates mud to promote pins-mediated mitotic spindle orientation in Drosophila, independent of Yorkie.Down-regulation of LATS kinases alters p53 to promote cell migration.The mob as tumor suppressor gene is essential for early development and regulates tissue growth in Drosophila.Aurora A kinase (AURKA) in normal and pathological cell division.Two functional coding single nucleotide polymorphisms in STK15 (Aurora-A) coordinately increase esophageal cancer risk.A double-edged sword: how oncogenes and tumor suppressor genes can contribute to chromosomal instabilityAurora kinase inhibitors: identification and preclinical validation of their biomarkers.CDK1 phosphorylation of YAP promotes mitotic defects and cell motility and is essential for neoplastic transformation.Silencing of the Lats2 tumor suppressor overrides a p53-dependent oncogenic stress checkpoint and enables mutant H-Ras-driven cell transformation.Making the Auroras glow: regulation of Aurora A and B kinase function by interacting proteins.
P2860
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P2860
The centrosomal protein Lats2 is a phosphorylation target of Aurora-A kinase.
description
2004 nî lūn-bûn
@nan
2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
The centrosomal protein Lats2 is a phosphorylation target of Aurora-A kinase.
@ast
The centrosomal protein Lats2 is a phosphorylation target of Aurora-A kinase.
@en
The centrosomal protein Lats2 is a phosphorylation target of Aurora-A kinase.
@nl
type
label
The centrosomal protein Lats2 is a phosphorylation target of Aurora-A kinase.
@ast
The centrosomal protein Lats2 is a phosphorylation target of Aurora-A kinase.
@en
The centrosomal protein Lats2 is a phosphorylation target of Aurora-A kinase.
@nl
prefLabel
The centrosomal protein Lats2 is a phosphorylation target of Aurora-A kinase.
@ast
The centrosomal protein Lats2 is a phosphorylation target of Aurora-A kinase.
@en
The centrosomal protein Lats2 is a phosphorylation target of Aurora-A kinase.
@nl
P2093
P2860
P1433
P1476
The centrosomal protein Lats2 is a phosphorylation target of Aurora-A kinase
@en
P2093
Hiroshi Nojima
Norikazu Yabuta
Shingo Toji
Souichi Nishihara
Susumu Suzuki
Toshiko Kobayashi
Toshiya Hosomi
P2860
P304
P356
10.1111/J.1356-9597.2004.00732.X
P577
2004-05-01T00:00:00Z