Moenomycin family antibiotics: chemical synthesis, biosynthesis, and biological activity - Test2 - elhamkhani - TriplyDB

Moenomycin family antibiotics: chemical synthesis, biosynthesis, and biological activity

Moenomycin family antibiotics: chemical synthesis, biosynthesis, and biological activity

http://www.wikidata.org/entity/Q34329962

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Glycosyltransferases and Transpeptidases/Penicillin-Binding Proteins: Valuable Targets for New Antibacterials Antibacterial Discovery and Development: From Gene to Product and Back Insights into the Mechanism of the Antibiotic-Synthesizing Enzyme MoeO5 from Crystal Structures of Different Complexes Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5.Generation and study of the strains of streptomycetes - heterologous hosts for production of moenomycin.Genes for biosynthesis of butenolide-like signalling molecules in Streptomyces ghanaensis, their role in moenomycin production.Primer preactivation of peptidoglycan polymerases.Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity Targeting Bacterial Cell Wall Peptidoglycan Synthesis by Inhibition of Glycosyltransferase Activity.Multidrug Intrinsic Resistance Factors in Staphylococcus aureus Identified by Profiling Fitness within High-Diversity Transposon Libraries.Tuning the moenomycin pharmacophore to enable discovery of bacterial cell wall synthesis inhibitors ABC transporter genes from Streptomyces ghanaensis moenomycin biosynthetic gene cluster: roles in antibiotic production and export.Pleiotropic regulatory genes bldA, adpA and absB are implicated in production of phosphoglycolipid antibiotic moenomycin.Insights into naturally minimised Streptomyces albus J1074 genome.Moenomycin resistance mutations in Staphylococcus aureus reduce peptidoglycan chain length and cause aberrant cell division.MoeH5: a natural glycorandomizer from the moenomycin biosynthetic pathway Viable screening targets related to the bacterial cell wall.Prospects for new antibiotics: a molecule-centered perspective.Bioactive oligosaccharide natural products.Prospects for novel inhibitors of peptidoglycan transglycosylases Pseudomonas aeruginosa: targeting cell-wall metabolism for new antibacterial discovery and development.Antibiotic Effects on Methicillin-Resistant Staphylococcus aureus Cytoplasmic Peptidoglycan Intermediate Levels and Evidence for Potential Metabolite Level Regulatory Loops.Evolution of cyclizing 5-aminolevulinate synthases in the biosynthesis of actinomycete secondary metabolites: outcomes for genetic screening techniques Structural Insights into Inhibition of Escherichia coli Penicillin-binding Protein 1B.Hierarchal clustering yields insight into multidrug-resistant bacteria isolated from a cattle feedlot wastewater treatment system.Tandem prenyltransferases catalyze isoprenoid elongation and complexity generation in biosynthesis of quinolone alkaloids.The B12-Radical SAM Enzyme PoyC Catalyzes Valine Cβ-Methylation during Polytheonamide Biosynthesis.Synthesis and biological evaluation of indole core-based derivatives with potent antibacterial activity against resistant bacterial pathogens.Effect of the lipid II sugar moiety on bacterial transglycosylase: the 4-hydroxy epimer of lipid II is a TGase inhibitor.A gene cluster for the biosynthesis of moenomycin family antibiotics in the genome of teicoplanin producer Actinoplanes teichomyceticus.The transpeptidase PbpA and non-canonical transglycosylase RodA of Mycobacterium tuberculosis play important roles in regulating bacterial cell lengths.Testing the utility of site-specific recombinases for manipulations of genome of moenomycin producer Streptomyces ghanaensis ATCC14672.Enzymatic synthesis of lipid II and analogues.Streptomyces ghanaensis pleiotropic regulatory gene wblA gh influences morphogenesis and moenomycin production

P2860

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P2860

Moenomycin family antibiotics: chemical synthesis, biosynthesis, and biological activity

http://www.wikidata.org/entity/Q34329962

description

2010 nî lūn-bûn

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2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2010 թվականի օգոստոսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Moenomycin family antibiotics: chemical synthesis, biosynthesis, and biological activity

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Moenomycin family antibiotics: chemical synthesis, biosynthesis, and biological activity

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Moenomycin family antibiotics: chemical synthesis, biosynthesis, and biological activity

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Moenomycin family antibiotics: chemical synthesis, biosynthesis, and biological activity

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Natural Product Reports

P1476

Moenomycin family antibiotics: chemical synthesis, biosynthesis, and biological activity

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Bohdan Ostash

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Suzanne Walker

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P2860

Multimodular penicillin-binding proteins: an enigmatic family of orthologs and paralogs

Structural insight into the transglycosylation step of bacterial cell-wall biosynthesis

Crystal structure of a peptidoglycan glycosyltransferase suggests a model for processive glycan chain synthesis

Structural Analysis of the Contacts Anchoring Moenomycin to Peptidoglycan Glycosyltransferases and Implications for Antibiotic Design

Identification of dynamic structural motifs involved in peptidoglycan glycosyltransfer

Characterization of the active site of S. aureus monofunctional glycosyltransferase (Mtg) by site-directed mutation and structural analysis of the protein complexed with moenomycin

Crystal structure of the membrane-bound bifunctional transglycosylase PBP1b from Escherichia coli.

Functional and Structural Analysis of a Key Region of the Cell Wall Inhibitor Moenomycin

Formation of the glycan chains in the synthesis of bacterial peptidoglycan

Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)

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1594-1617

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10.1039/C001461N

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11

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27

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