Depletion of intracellular ascorbate by the carcinogenic metals nickel and cobalt results in the induction of hypoxic stress.
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Hypoxia-based strategies for angiogenic induction: the dawn of a new era for ischemia therapy and tissue regenerationThe possible mechanisms underlying the impairment of HIF-1α pathway signaling in hyperglycemia and the beneficial effects of certain therapiesAscorbate depletion: a critical step in nickel carcinogenesis?Advances in carcinogenic metal toxicity and potential molecular markersRegulation of Multi-drug Resistance in hepatocellular carcinoma cells is TRPC6/Calcium Dependent.Down-regulation of the expression of the FIH-1 and ARD-1 genes at the transcriptional level by nickel and cobalt in the human lung adenocarcinoma A549 cell lineGenetic and epigenetic mechanisms in metal carcinogenesis and cocarcinogenesis: nickel, arsenic, and chromiumInhibition of 2-oxoglutarate dependent oxygenasesNickel and the microbial toxin, MALP-2, stimulate proangiogenic mediators from human lung fibroblasts via a HIF-1alpha and COX-2-mediated pathwayBioavailability, intracellular mobilization of nickel, and HIF-1α activation in human lung epithelial cells exposed to metallic nickel and nickel oxide nanoparticlesMetal rich particulate matter impairs acetylcholine-mediated vasorelaxation of microvessels in miceEndoplasmic reticulum thiol oxidase deficiency leads to ascorbic acid depletion and noncanonical scurvy in miceHypoxia-inducible factor prolyl-hydroxylase 2 senses high-salt intake to increase hypoxia inducible factor 1alpha levels in the renal medullaThe Loss of HIF1α Leads to Increased Susceptibility to Cadmium-Chloride-Induced Toxicity in Mouse Embryonic FibroblastsExposure to nickel, chromium, or cadmium causes distinct changes in the gene expression patterns of a rat liver derived cell lineMetal ions-stimulated iron oxidation in hydroxylases facilitates stabilization of HIF-1 alpha proteinWhole adult organism transcriptional profiling of acute metal exposures in male zebrafishHypoxia-inducible factor modulates tubular cell survival in cisplatin nephrotoxicity.Global gene expression profiling in human lung cells exposed to cobalt.A yeast three-hybrid system that reconstitutes mammalian hypoxia inducible factor regulatory machineryRole of hypoxia-inducible factor 1{alpha} in modulating cobalt-induced lung inflammation.Iron- and 2-oxoglutarate-dependent dioxygenases: an emerging group of molecular targets for nickel toxicity and carcinogenicity.A mini review focused on the proangiogenic role of silicate ions released from silicon-containing biomaterialsRecent advances in arsenic trioxide encapsulated nanoparticles as drug delivery agents to solid cancersLncRNA MEG3 downregulation mediated by DNMT3b contributes to nickel malignant transformation of human bronchial epithelial cells via modulating PHLPP1 transcription and HIF-1α translation.Acute cobalt-induced lung injury and the role of hypoxia-inducible factor 1alpha in modulating inflammationNatural product-derived small molecule activators of hypoxia-inducible factor-1 (HIF-1)Analysis of hypoxia and hypoxia-like states through metabolite profiling.Toxoplasma gondii activates hypoxia-inducible factor (HIF) by stabilizing the HIF-1alpha subunit via type I activin-like receptor kinase receptor signaling.Effects of cellular iron deficiency on the formation of vascular endothelial growth factor and angiogenesis. Iron deficiency and angiogenesis.Hypoxia-inducible factor activation protects the kidney from gentamicin-induced acute injury.Distinct regulatory mechanisms of the human ferritin gene by hypoxia and hypoxia mimetic cobalt chloride at the transcriptional and post-transcriptional levelsInsulin regulates hypoxia-inducible factor-1α transcription by reactive oxygen species sensitive activation of Sp1 in 3T3-L1 preadipocyte.Hypoxic preconditioning with cobalt of bone marrow mesenchymal stem cells improves cell migration and enhances therapy for treatment of ischemic acute kidney injury.Vitamin C is dispensable for oxygen sensing in vivoExposure to cobalt causes transcriptomic and proteomic changes in two rat liver derived cell lines.Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activationChromium in drinking water: sources, metabolism, and cancer risksHypoxia induces tumor and endothelial cell migration in a semaphorin 3F- and VEGF-dependent manner via transcriptional repression of their common receptor neuropilin 2.Nickel ions selectively inhibit lipopolysaccharide-induced interleukin-6 production by decreasing its mRNA stability.
P2860
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P2860
Depletion of intracellular ascorbate by the carcinogenic metals nickel and cobalt results in the induction of hypoxic stress.
description
2004 nî lūn-bûn
@nan
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Depletion of intracellular asc ...... e induction of hypoxic stress.
@ast
Depletion of intracellular asc ...... e induction of hypoxic stress.
@en
Depletion of intracellular asc ...... e induction of hypoxic stress.
@nl
type
label
Depletion of intracellular asc ...... e induction of hypoxic stress.
@ast
Depletion of intracellular asc ...... e induction of hypoxic stress.
@en
Depletion of intracellular asc ...... e induction of hypoxic stress.
@nl
prefLabel
Depletion of intracellular asc ...... e induction of hypoxic stress.
@ast
Depletion of intracellular asc ...... e induction of hypoxic stress.
@en
Depletion of intracellular asc ...... e induction of hypoxic stress.
@nl
P2093
P2860
P921
P356
P1476
Depletion of intracellular asc ...... e induction of hypoxic stress.
@en
P2093
Anatoly Zhitkovich
James M Phang
Kazimierz S Kasprzak
Konstantin Salnikow
Richard K Bruick
Steven P Donald
P2860
P304
40337-40344
P356
10.1074/JBC.M403057200
P407
P577
2004-07-22T00:00:00Z