Antitumor efficacy and acute toxicity of the novel dipeptide melphalanyl-p-L-fluorophenylalanine ethyl ester (J1) in vivo.

Antitumor efficacy and acute toxicity of the novel dipeptide melphalanyl-p-L-fluorophenylalanine ethyl ester (J1) in vivo.

Item
http://www.wikidata.org/entity/Q34338552
In vitro and in vivo antitumor activity of a novel alkylating agent, melphalan-flufenamide, against multiple myeloma cells.Aminopeptidase N (CD13) as a target for cancer chemotherapy.First-in-human, phase I/IIa clinical study of the peptidase potentiated alkylator melflufen administered every three weeks to patients with advanced solid tumor malignancies.In vitro and in vivo activity of melflufen (J1)in lymphomaUse of the in vivo hollow fiber assay in natural products anticancer drug discovery.Correlative effect between in vivo hollow fiber assay and xenografts assay in drug screening.Preclinical activity of melflufen (J1) in ovarian cancer.In vitro and in vivo anti-leukemic activity of the peptidase-potentiated alkylator melflufen in acute myeloid leukemia.A novel alkylating agent Melflufen induces irreversible DNA damage and cytotoxicity in multiple myeloma cellsMelflufen - a peptidase-potentiated alkylating agent in clinical trials.A New Approach to the Efficient Method for the Asymmetric Synthesis of (S)-O-, M-, P-Fluorophenylalanines and Their 2-Methyl-substituted Analogs
P2860

Antitumor efficacy and acute toxicity of the novel dipeptide melphalanyl-p-L-fluorophenylalanine ethyl ester (J1) in vivo.

Item
http://www.wikidata.org/entity/Q34338552
description
2004 nî lūn-bûn
@nan
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Antitumor efficacy and acute t ...... nine ethyl ester (J1) in vivo.
@ast
Antitumor efficacy and acute t ...... nine ethyl ester (J1) in vivo.
@en
Antitumor efficacy and acute t ...... luorophenylalanine ethyl ester
@nl
type
label
Antitumor efficacy and acute t ...... nine ethyl ester (J1) in vivo.
@ast
Antitumor efficacy and acute t ...... nine ethyl ester (J1) in vivo.
@en
Antitumor efficacy and acute t ...... luorophenylalanine ethyl ester
@nl
prefLabel
Antitumor efficacy and acute t ...... nine ethyl ester (J1) in vivo.
@ast
Antitumor efficacy and acute t ...... nine ethyl ester (J1) in vivo.
@en
Antitumor efficacy and acute t ...... luorophenylalanine ethyl ester
@nl
P1433
P1476
P2093
P2888
P304
P31
P356
P433
P478
P50
P577
P6179
P698
P356
P1433
P1476
Antitumor efficacy and acute t ...... nine ethyl ester (J1) in vivo.
@en
P2093
P2888
P304
P31
P356
10.1023/B:DRUG.0000036683.10945.BB
P433
P478
P50
P577
P6179
P698