An automated flow for directed evolution based on detection of promiscuous scaffolds using spatial and electrostatic properties of catalytic residues.

An automated flow for directed evolution based on detection of promiscuous scaffolds using spatial and electrostatic properties of catalytic residues.

Item
http://www.wikidata.org/entity/Q34343512
Structural phylogeny by profile extraction and multiple superimposition using electrostatic congruence as a discriminator.A measure of the broad substrate specificity of enzymes based on 'duplicate' catalytic residuesA computational module assembled from different protease family motifs identifies PI PLC from Bacillus cereus as a putative prolyl peptidase with a serine protease scaffoldThe dipeptidyl peptidase IV inhibitors vildagliptin and K-579 inhibit a phospholipase C: a case of promiscuous scaffolds in proteins.Sequence/structural analysis of xylem proteome emphasizes pathogenesis-related proteins, chitinases and β-1, 3-glucanases as key players in grapevine defense against Xylella fastidiosa.DOCLASP - Docking ligands to target proteins using spatial and electrostatic congruence extracted from a known holoenzyme and applying simple geometrical transformations.Bioengineering of plant (tri)terpenoids: from metabolic engineering of plants to synthetic biology in vivo and in vitro.Biological messiness vs. biological genius: Mechanistic aspects and roles of protein promiscuity.Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently.Directed evolution induces tributyrin hydrolysis in a virulence factor of Xylella fastidiosa using a duplicated gene as a template.The walnut (Juglans regia) genome sequence reveals diversity in genes coding for the biosynthesis of non-structural polyphenols.
P2860

An automated flow for directed evolution based on detection of promiscuous scaffolds using spatial and electrostatic properties of catalytic residues.

Item
http://www.wikidata.org/entity/Q34343512
description
2012 nî lūn-bûn
@nan
2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
An automated flow for directed ...... perties of catalytic residues.
@ast
An automated flow for directed ...... perties of catalytic residues.
@en
An automated flow for directed ...... perties of catalytic residues.
@nl
type
label
An automated flow for directed ...... perties of catalytic residues.
@ast
An automated flow for directed ...... perties of catalytic residues.
@en
An automated flow for directed ...... perties of catalytic residues.
@nl
prefLabel
An automated flow for directed ...... perties of catalytic residues.
@ast
An automated flow for directed ...... perties of catalytic residues.
@en
An automated flow for directed ...... perties of catalytic residues.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932
P356
P1433
P1476
An automated flow for directed ...... perties of catalytic residues.
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0040408
P407
P433
P478
P577
P5875
P698
P921
P932